Abstract: The present invention discloses a design and optimization method based on a self supporting ellipsoidal cavity structure. First, a three-dimensional model with initialized self supporting ellipsoidal cavities is represented by a function; then the structure of the object is analyzed, modeled and optimized by the continuity and differentiability of the function; the internal lightweighting of the model is carried out with the self supporting ellipsoidal cavities, without the need of adding a supporting structure, thus avoiding waste of materials; the intersection of self supporting ellipsoids is strictly controlled to avoid damage to self supportability within the model due to intersection; and finally, the above modeling problem is geometrically optimized to obtain an internal shape of the object optimized under given constraint conditions. The present invention greatly shortens the design and optimization cycle of the hole structure, realizes self supporting for the internal cavities of the model.

Abstract: An electronic device includes a first housing and a second housing connected to the first housing. An accommodation cavity is formed between the first housing and the second housing. The electronic device further includes a heat generation member arranged in the accommodation cavity and a flow channel arranged in the first housing. The flow channel is configured to accommodate heat exchange liquid and dissipate heat for the heat generation member through the heat exchange liquid.

Abstract: The present invention discloses a boundary layer mesh generation method based on an anisotropic volume harmonic field, and belongs to the technical filed of computational fluid dynamics, numerical simulation, computer aided design and manufacturing. First, a boundary surface mesh of the Minkowski sum is used to construct a tetrahedral background mesh required for solving volume harmonic fields, then an anisotropic tensor is automatically added according to the actual demand, the anisotropic volume harmonic field is calculated under the control of the tensor, and finally, the advancing direction required by the boundary layer mesh is generated in combination with special weighted Laplace smoothing.

Abstract: The present invention relates to an efficient design and optimization algorithm framework of multi-scale porous structures. Firstly, initialized parameters are input by the user to obtain an initial porous structure through the design module. Then, the structure and external physical conditions defined by the user are transmitted to the analysis module to conduct mechanical response analysis of the porous structure. Next, an objective function and constraint functions of the optimization module are defined according to application requirements, and gradient information obtained by the analysis module is input to drive the operation of the optimization module. Finally an optimal multi-scale porous structure is obtained.

Abstract: The present invention discloses a method, device and computer readable storage medium (CRSM) for generating a volume foliation. The method comprises: constructing a pants decomposition graph on a smooth closed surface S of genus g>1, wherein the surface S has g handles, and the pants are a genus-zero triangular mesh surface with g boundaries; constructing an initial mapping f0:(T,g)?(Gr, h) from a tetrahedral mesh T to a graph Gr by a process of extending a topological disk Dk into a solid cylinder Ck; evolving the initial mapping into a generalized harmonic map by the nth iterative mapping; and obtaining a volume foliation of the tetrahedral mesh T from preimages of all nodes of a metric graph (Gr, h) and points on edges of the metric graph (Gr, h) under the generalized harmonic map f.

Abstract: An efficient method for representation and optimization of porous structures belongs to the field of computer aided design. Firstly, a representation method of a multi-scale porous structure described by a function is provided. Based on the function representation, an optimization frame is designed. Then, an optimization problem model is established by taking structural energy minimization as a goal and taking a volume and a gradient as constraints. Finally, topological optimization is conducted firstly, and then geometric optimization is conducted. The topology and the thickness of the porous structure are optimized to obtain an optimization model filled with the porous structure. The present invention completely represents, analyzes, optimizes and stores the porous structure by functions, which greatly reduces the calculation complexity and greatly shortens the design and optimization period.

Abstract: The present invention discloses a method, device and computer readable storage medium (CRSM) for generating a volume foliation. The method comprises: constructing a pants decomposition graph on a smooth closed surface S of genus g>1, wherein the surface S has g handles, and the pants are a genus-zero triangular mesh surface with g boundaries; constructing an initial mapping f0:(T, g)?(Gr, h) from a tetrahedral mesh T to a graph Gr by a process of extending a topological disk Dk into a solid cylinder Ck; evolving the initial mapping into a generalized harmonic map by the nth iterative mapping; and obtaining a volume foliation of the tetrahedral mesh T from preimages of all nodes of a metric graph (Gr, h) and points on edges of the metric graph (Gr, h) under the generalized harmonic map f.

Abstract: A wearable ultrasonic haptic feedback system includes: a substrate layer; an ultrasonic transmitter matrix layer disposed above the substrate layer and including a plurality of ultrasonic transmitters; a converter matrix layer disposed below the substrate layer and including a plurality of converters; a first control unit connected with the ultrasonic transmitter matrix layer; an RF receiver connected with the first control unit; a second control unit connected with the converter matrix layer; and an RF transmitter connected with the second control unit. The ultrasonic transmitters are configured to be controlled by the first control unit to transmit an ultrasonic signal of a preset frequency respectively. The converters are configured to be respectively controlled by the second control unit to sense an ultrasonic signal and convert the sensed ultrasonic signal to an electrical signal. The RF transmitter is configured to transmit the electrical signal through an RF signal of a preset frequency.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.