Patents by Inventor Nagender Yerram

Nagender Yerram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 6235508
    Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture. Quinoline and quinolone compounds are useful as photosensitizers in this method. With certain photosensitizers a blocking agent may also be employed.
    Type: Grant
    Filed: September 15, 1998
    Date of Patent: May 22, 2001
    Assignee: Baxter International Inc.
    Inventors: Samuel O. Sowemimo-Coker, Nagender Yerram, Raymond P. Goodrich, Jr., Matthew S. Platz
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 6187572
    Abstract: A method is provided for inactivating viral and/or bacterial contamination in blood cellular matter, such as erythrocytes and platelets, or protein fractions. The cells or protein fractions are mixed with chemical sensitizers, frozen or freeze-dried, and irradiated with, for example, UV, visible, gamma or X-ray radiation while in the solid state.
    Type: Grant
    Filed: April 14, 1993
    Date of Patent: February 13, 2001
    Assignee: Baxter International Inc.
    Inventors: Matthew S. Platz, Raymond P. Goodrich, Jr., Nagender Yerram
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 6169109
    Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
    Type: Grant
    Filed: September 4, 1998
    Date of Patent: January 2, 2001
    Assignee: Baxter International Inc.
    Inventors: Sang Chul Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 5955256
    Abstract: Viral, bacterial and parasitic contaminants in blood and cell culture containing compositions are inactivated by adding a photosensitizer and a blocking agent to the composition and irradiating the resulting mixture with electromagnetic radiation. Blocking agents reduce photolysis of the photosensitizer by mechanisms not involving the quenching of reactive oxygen species. The blocking agents reduce photolysis which occurs by ring opening. Preferred photosensitizers are quinoline or quinolone.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 21, 1999
    Assignee: Baxter International Inc.
    Inventors: Samuel O. Sowemimo-Coker, Nagender Yerram, Raymond P. Goodrich, Jr., Matthew S. Platz
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 5869701
    Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 9, 1999
    Assignee: Baxter International Inc.
    Inventors: Sang Chul Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 5789601
    Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: August 4, 1998
    Assignee: Baxter International Inc.
    Inventors: Sang Chul Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila
  • Method of inactivation of viral and bacterial blood contaminants
    Patent number: 5587490
    Abstract: A compound is provided for inactivating viral, bacterial or other contamination in cells, body fluids or fractions thereof. The compound comprises a psoralen with a single substituent that is either a quaternary phosphonium or ammonium moiety, and at least one substituent that is a halogen. The compound selectively binds to the contaminant, and upon activation by irradiation, damages the contaminant.
    Type: Grant
    Filed: December 10, 1993
    Date of Patent: December 24, 1996
    Assignee: Credit Managers Association of California
    Inventors: Raymond P. Goodrich, Jr., Matthew S. Platz, Nagender Yerram, Roger W. Hackett, Marjan van Borssum Waalkes, Christine M. Williams-Hughes, Victoria A. Wong
  • Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
    Patent number: 5516629
    Abstract: A method for photoinactivating viral and/or bacterial contaminants in blood, blood products or cell cultures is presented. The blood, blood product or cell culture is mixed with an halogenated coumarin sensitizer and irradiated with UV light to inactivate the viral and/or bacterial contaminants.
    Type: Grant
    Filed: September 22, 1994
    Date of Patent: May 14, 1996
    Assignee: Cryopharm Corporation
    Inventors: Sang C. Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila