Abstract: A computer-implemented method, in accordance with one embodiment, includes collecting data relating to development of a software product, the collected data including a plurality of different types of data relating to the development of the software product. A portion of the collected data is selected based on a characteristic of an intended user, the portion of the collected data including a plurality of the types of data. The selected portion of the collected data is transformed into data visualizations representing the data, the different types of the data having different data visualizations relative to one another. The data visualizations are output in a single visual representation for display to the intended user.

Abstract: A computer-implemented method, computer system, and computer program product for managing a database are disclosed. Features thereof include selecting data lines for analytics, each data line including original data, and adding, to each of the selected data lines, a set of additional bytes to represent metadata about a corresponding one of the data lines. The features further include receiving a request to receive a first data line, and reading a first set of additional bytes corresponding to the first data line.

Abstract: Methods, computer program products, and/or systems are provided that perform the following operations: reading lines of code included in a collection of source code; identifying an assigned tag in the collection of source code; identifying a start tag location and an end tag location associated with the assigned tag, wherein the lines of code included between the start tag location and the end tag location identify a code block; processing the code block to generate logging data for the code block based, at least in part, on the assigned tag; and providing the logging data for linking to executable byte code compiled from the collection of source code, wherein the logging data is used to log code data relating to the code block during execution of the executable byte code.

Abstract: Techniques for data evaluation using machine learning are provided. A textual document is received, and the textual document is parsed using a recurrent neural network (RNN) to extract a plurality of keywords. A first subset of keywords which are known by a user and a second subset of keywords which are unknown by the user are each identified. A summary of the textual document is generated based on the second subset of keywords. The summary is output, comprising: outputting information related to a first keyword of the second subset of keywords and, upon determining that the first keyword is understood by the user, outputting information related to a second keyword of the second subset of keywords.

Abstract: Methods, computer program products, and/or systems are provided that perform the following operations: reading lines of code included in a collection of source code; identifying an assigned tag in the collection of source code; identifying a start tag location and an end tag location associated with the assigned tag, wherein the lines of code included between the start tag location and the end tag location identify a code block; processing the code block to generate logging data for the code block based, at least in part, on the assigned tag; and providing the logging data for linking to executable byte code compiled from the collection of source code, wherein the logging data is used to log code data relating to the code block during execution of the executable byte code.

Abstract: Techniques for data evaluation using machine learning are provided. A textual document is received, and the textual document is parsed using a recurrent neural network (RNN) to extract a plurality of keywords. A first subset of keywords which are known by a user and a second subset of keywords which are unknown by the user are each identified. A summary of the textual document is generated based on the second subset of keywords. The summary is output, comprising: outputting information related to a first keyword of the second subset of keywords and, upon determining that the first keyword is understood by the user, outputting information related to a second keyword of the second subset of keywords.

Abstract: A computer-implemented method, computer system, and computer program product for managing a database are disclosed. Features thereof include selecting data lines for analytics, each data line including original data, and adding, to each of the selected data lines, a set of additional bytes to represent metadata about a corresponding one of the data lines. The features further include receiving a request to receive a first data line, and reading a first set of additional bytes corresponding to the first data line.

Abstract: Embodiments of the present invention provide a computer system, a computer program product, and a method that comprises receiving and storing input data from at least two users; calculating a risk score for each identified risk in the received data based on priority risk factors affecting respectively identified risks; dynamically optimizing a risk analysis of the received input for multiple users within a user interface of a computing device by recalculating risk scores based on the received data and identified risks; and generating a notification for the user interface of the computing device based on the dynamic optimization of the risk analysis of the received input.

Abstract: A method for inhibiting ectopic calcification of bodily organs caused by elevated LDL cholesterol is provided. The method includes administering an LDL lowering agent to a patient, comprising a PCSK9 inhibitor selected from Evolocumab, Alirocumab, Praluent, Repatha Pushtonix, Repatha autoinjector, and combinations of the foregoing.

Abstract: Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.

Abstract: Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.

Abstract: A method for inhibiting ectopic calcification of bodily organs caused by elevated LDL cholesterol is provided. The method includes administering an LDL lowering agent to a patient, comprising a PCSK9 inhibitor selected from Evolocumab, Alirocumab, Praluent, Repatha Pushtonix, Repatha autoinjector, and combinations of the foregoing.

Abstract: Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.

Abstract: Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.

Abstract: The present invention relates to methods for inhibiting stenosis, obstruction, or calcification of a valve following implantation of a valve prosthesis or a native valve which develops disease via the Lrp5/Wnt Pathway in the presence of elevated lipids due to elevated Low Density Lipoprotein. This invention involves dispensing a combination of medications to target inflammation and attachment of the target cell and the secondary drugs to inhibit proliferation and calcification on an elastical stent, gortex graft or valve leaflet. The combination therapy inhibits bioprosthesis and native valve calcification with improvement of the longevity of the prosthetic material including the stent, the native valve, and the gortex covering. The valve prosthesis and or gortex graft is mounted on the elastical stent or prosthesis such that the elastical stent is connected to the valve.

Abstract: Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both.

Abstract: The present invention relates to methods for inhibiting stenosis, obstruction, or calcification of a valve following implantation of a valve prosthesis which may involve disposing a coating composition which is a combination of two different drugs one to target inflammation and attachment of the target cell and the second drug to inhibit proliferation and calcification on an elastical stent, gortex graft or valve leaflet, the combination effect of the two drug therapies incorporated into the polymer to attach to the bioprosthesis will improve the efficacy of the inhibition of calcification and the improvement of the longevity of the prosthetic material including the stent, the valve, and the gortex covering. The valve prosthesis and or gortex graft is mounted on the elastical stent or prosthesis such that the elastical stent is in contact with the valve.

Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.