Abstract: The present invention relates to immediate release compositions comprising a pre-complex comprising a polymeric polycarboxylate and an aminophenylalkanol vasoconstrictor in a solid chewable matrix of pharmaceutically-acceptable carrier ingredients wherein the aminophenylalkanol vasoconstrictor and polymeric polycarboxylate are in a weight ratio of from about 5:1 to about 1:10 and wherein the pre-complex is dissociable at a pH of from about 4.5 to about 6.8, releasing the aminophenylalkanol vasoconstrictor.

Abstract: Methods for aiding periodontal tissue regeneration with compositions containing bioresorbable polymers, leachable solvents, and bioavailable drug actives. The compositions useful for these methods are characterized by becoming harder upon contact with the periodontal tissue such that the composition is effective for aiding tissue regeneration and by releasing a therapeutically-effective amount of drug active agent.

Abstract: This disclosure relates to drug-polymer matrix compositions comprising an active ingredient having an amine or amido group and a pharmaceutically acceptable copolymer having a plurality of carboxylic acid and ester groups wherein the matrix dissociates in a media having a pH of less than 4, thereby releasing the active ingredient into the media.

Abstract: This invention relates to compositions and methods for treating diseases of the oral cavity in humans and lower animals using a glycerol monooleate gel for releasing drugs in the oral cavity.

Abstract: This invention relates to compositions/devices and methods for treating diseases of the oral cavity in humans and lower animals using polylactide/glycolide compositions/devices for releasing drugs in the oral cavity.

Abstract: This invention relates to compositions/devices and methods for treating diseases of the oral cavity in humans and lower animals using polypropenoic acid compositions/devices for releasing drugs in the oral cavity.

Abstract: This invention relates to devices/compositions and methods for treating diseases of the oral cavity in humans and lower animals using non-biodegradable devices/compositions which are biocompatible but not bioerodible for releasing drugs in or around a periodontol pocket or gingival sulcus.

Abstract: This invention relates to compositions/devices and methods for treating diseases of the oral cavity in humans and lower animals using polypropenoic acid compositions/devices for releasing drugs in the oral cavity.

Abstract: This disclosure relates to drug-polymer matrix compositions comprising an active ingredient having an amine or amido group and a pharmaceutically acceptable copolymer having a plurality of carboxylic acid and ester groups wherein the matrix dissociates in a media having a pH of less than 4, thereby releasing the active ingredient into the media.

Abstract: The present disclosure relates to an external analgesic solid stick composition for the topical administration of active analgesic agents. The compositions are dimensionally stable solid compositions comprising an external analgesic agent incorporated into a non-reactive hydrophobic wax matrix.

Abstract: Anti-acne preparations include finely divided, dispersed particles of benzoyl peroxide and finely divided, dispersed particles of salicylic acid in an aqueous gel formed from carboxy vinyl polymer resins. The gels are prepared without loss of salicylic acid by fully hydrating the resin in an aqueous medium and allowing the resin to gel in the absence of an alkaline neutralizing agent.

Abstract: Osmotically driven active agent dispenser for use in an aqueous environment that pumps a solution of active agent, such as a drug, at a predetermined, constant rate. The dispenser is in the form of a coated tablet comprising: a core of an osmotically effective active agent composition; and an inexpandable wall that encloses the core, has a controlled permeability to water and includes means, such as brittleness or sites of structural weakness, that is responsive to the pressure generated within the dispenser by imbibition of water from the environment by the core through the wall to form at least one, and usually many, passageways in situ in the wall through which the active agent composition in solution is pumped osmotically at a rate that is substantially dependent of the rate at which water is being imbibed into the dispenser.

Abstract: A process for dispensing medicaments in aerosol form for inhalation therapy is disclosed. The process comprises: providing a hollow elongate housing having air inlet and air outlet passages; generating a positive pressure, air-stream between the inlet and outlet passages; rotationally releasing medicament from a container within the housing into the air-stream; and inserting the outlet passage into the oral or nasal cavity of the patient.