Patents by Inventor Nam-Hai Chua

Nam-Hai Chua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8586824
    Abstract: A group of genes including GhCIR1 from cotton (Gossypium hirsutum), and AtCIR1 and AtCIR2 from Arabidopsis thaliana promote shoot regeneration in plants even in the absence of cytokinin. In the presence of cytokinin, the genes significantly improve transformation efficiency. The genes can be used as an enhancer as well as a selectable marker of transformation in plants. The proteins encoded by the novel genes have a homeodomain (HD) at the N-terminus and a highly divergent domain at the C-terminus. The proteins share a common structural motif.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: November 19, 2013
    Assignee: Temasek Life Sciences Laboratory
    Inventors: Lianghui Ji, Lin Cai, Nam-Hai Chua
  • Patent number: 8581037
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: November 12, 2013
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua
  • Patent number: 8431773
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: April 30, 2013
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua
  • Publication number: 20120272403
    Abstract: The present invention relates to methods for the regeneration and Agrobacterium-mediated transformation of plants in the genera of Jatropha, more specifically, in Jatropha curcas.
    Type: Application
    Filed: July 3, 2012
    Publication date: October 25, 2012
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Hui Zhu MAO, Jian YE, Nam Hai CHUA
  • Publication number: 20120240288
    Abstract: The present invention relates to the field of controlling pests, such as insects, using a virus to express pest genes in hosts. More specifically, the present invention relates to a method for rapidly screening for pest genes which can lead to mortality of the pest when the pest has ingested host tissues expressing virus-linked pest gene sequences. The present invention also relates to a method for controlling pests by viral expression of target pest sequences to modify endogenous expression of pest genes in cells or tissues of the pest.
    Type: Application
    Filed: September 15, 2010
    Publication date: September 20, 2012
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Jian Ye, Nam-Hai Chua, Jing Qu, Shi-Qiang Gao
  • Publication number: 20120102594
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Application
    Filed: January 11, 2012
    Publication date: April 26, 2012
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Jianru ZUO, Qi-Wen NIU, Giovanna FRUGIS, Nam-Hai CHUA
  • Publication number: 20120096595
    Abstract: The invention relates to the functional analysis of genes in cotton by employing the Virus Induced Gene Silencing (VIGS) method. More specifically this method induces gene silencing in cotton with the help of the Tobacco Rattle Virus (TRV) vectors RNA1 and RNA2 and phenotypic effects on the cotton plant can be analysed Moreover this invention also provides transient expression vector TRV RNA2 in order to transiently express genes in cotton plants and plant tissue under the influence of a strong subgenomic promoter.
    Type: Application
    Filed: June 10, 2010
    Publication date: April 19, 2012
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Jian Ye, Nam Hai Chua, Jing Qu, Yun Feng Geng, Yun Ping Bu
  • Patent number: 8101821
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: January 24, 2012
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua
  • Publication number: 20110265223
    Abstract: The present invention relates to the field of functional analysis of Jatropha genes on a genomic scale. More specifically, the present invention relates to a method for high-throughtput functional analysis of Jatropha curcas genes on a genomic scale using virus-induced gene silencing. The method involves use of the tobacco rattle virus (TRV).
    Type: Application
    Filed: December 16, 2009
    Publication date: October 27, 2011
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Jian Ye, Nam Hai Chua, JIng Qu
  • Publication number: 20110252506
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 13, 2011
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Jianru ZUO, Qi-Wen NIU, Giovanna FRUGIS, Nam-Hai CHUA
  • Publication number: 20110247099
    Abstract: The present invention relates to methods for the regeneration and Agrobacterium-mediated transformation of plants in the genera of Jatropha, more specifically, in Jatropha curcas.
    Type: Application
    Filed: December 15, 2009
    Publication date: October 6, 2011
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Hui Zhu Mao, Jian Ye, Nam Hai Chua
  • Patent number: 7977534
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: July 12, 2011
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua
  • Publication number: 20110162114
    Abstract: The invention relates to a method for producing a transformed plant cell. More particularly, the method involves the transformation of a plant cell with a Transformation Cassette which is targeted to plant plastids and which comprises a selection gene, for example isopentenyl transferase (IPT), and a transgene. After selection for transformed plastids, expression of a recombinase is induced in the plant cell, which leads to the excision of the selection gene from the plastid and the expression of the transgene in the plastid. The invention also provides cells and plants comprising the Transformation Cassette.
    Type: Application
    Filed: June 12, 2009
    Publication date: June 30, 2011
    Inventors: Simon Geir Moller, Nam-Hai Chua, Jodi Maple
  • Publication number: 20110078823
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Application
    Filed: September 23, 2010
    Publication date: March 31, 2011
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Jianru ZUO, Qi-Wen NIU, Giovanna FRUGIS, Nam-Hai CHUA
  • Publication number: 20100293662
    Abstract: A group of genes including GhCIR1 from cotton (Gossypium hirsutum), and AtCIR1 and AtCIR2 from Arabidopsis thaliana promote shoot regeneration in plants even in the absence of cytokinin. In the presence of cytokinin, the genes significantly improve transformation efficiency. The genes can be used as an enhancer as well as a selectable marker of transformation in plants. The proteins encoded by the novel genes have a homeodomain (HD) at the N-terminus and a highly divergent domain at the C-terminus. The proteins share a common structural motif.
    Type: Application
    Filed: February 13, 2006
    Publication date: November 18, 2010
    Applicant: TEMASEK LIFE SCIENCES LABORATORY
    Inventors: Lianghui Ji, Lin Cai, Nam-Hai Chua
  • Publication number: 20100269182
    Abstract: The present invention relates generally to chemical-inducible system and to methods of use in transgenic animals. More specifically, the present invention relates to a chimeric transcription factor that binds to a ligand and functions in ligand-dependent manner to induce expression of genes of interest under the control of a synthetic operator-promoter sequence. The expression of genes of interest can be tightly controlled by adding or removing the ligand.
    Type: Application
    Filed: July 2, 2008
    Publication date: October 21, 2010
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Alexander Emelyanov, Sergey Parinov, Nam-Hai Chua
  • Patent number: 7816580
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: October 19, 2010
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua
  • Publication number: 20100186125
    Abstract: The invention relates to a method for producing a transformed plant cell. More particularly, the method involves the transformation of a plant cell with a Transformation Cassette which is targeted to plant plastids and which comprises a selection gene, for example isopentenyl transferase (IPT), and a transgene. After selection for transformed plastids, expression of a recombinase is induced in the plant cell, which leads to the excision of the selection gene from the plastid and the expression of the transgene in the plastid. The invention also provides cells and plants comprising the Transformation Cassette.
    Type: Application
    Filed: December 14, 2007
    Publication date: July 22, 2010
    Inventors: Simon Moller, Nam-Hai Chua
  • Publication number: 20100169997
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Application
    Filed: March 12, 2010
    Publication date: July 1, 2010
    Applicant: THE ROCKEFELLER UNIVERSITY
    Inventors: Jianru ZUO, Qi-Wen NIU, Giovanna FRUGIS, Nam-Hai CHUA
  • Patent number: 7700829
    Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: April 20, 2010
    Assignee: The Rockefeller University
    Inventors: Jianru Zuo, Qi-Wen Niu, Giovanna Frugis, Nam-Hai Chua