Patents by Inventor Namal Nawana
Namal Nawana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11209416Abstract: Methods and devices for detecting a target agent of interest, e.g., a pathogen, in a sample are described herein. In some embodiments, a sensor is provided that can include a substrate, a graphene layer disposed on a surface of said substrate, and a protein bound to said graphene layer. The protein can be capable of binding to one or more target agents of interest, e.g., pathogens, etc. The binding of the protein to the one or more target agents of interest can generate a change in an electrical property of the graphene layer.Type: GrantFiled: July 26, 2018Date of Patent: December 28, 2021Assignee: Graphene-DX, Inc.Inventors: Mohammad E. Taslim, Mohammed Fotouhi, Mehdi Abedi, Reza Mollaaghababa, Bahram Fotouhi, Kashayar Javaherian, Edward Alvin Greenfield, Namal Nawana
-
Patent number: 11149318Abstract: In one aspect, a method of detecting a pathogen, e.g., listeria bacterium, chlamydia bacteria, gonorrhea bacteria and/or HPV, in a sample is disclosed, which comprises bringing a sample into contact with a graphene layer functionalized with an antibody exhibiting specific binding to the pathogen, monitoring electrical resistance of said antibody-functionalized graphene layer in response to interaction with said sample, and detecting presence of the pathogen in said sample by detecting a change in said electrical resistance indicative of interaction of the pathogen with said antibody-functionalized graphene layer. For example, a decrease of the electrical resistance of the graphene layer can indicate the presence of the pathogen in the sample under study. In some embodiments, a method according to the present teachings is capable of detecting pathogens, such as listeria bacteria, chlamydia bacteria, gonorrhea bacteria and HPV in a sample at a concentration as low as 4 cfu per 100 grams of a sample.Type: GrantFiled: January 29, 2019Date of Patent: October 19, 2021Assignee: GRAPHENE-DX, INC.Inventors: Mohammed Fotouhi, Mohammad E. Taslim, Mehdi Abedi, Edward Alvin Greenfield, Reza Mollaaghababa, Namal Nawana
-
Publication number: 20210293816Abstract: In one aspect, a sensor for detecting SARS-CoV-2 virus in a sample, e.g., a blood sample, is disclosed, which includes a graphene layer, a plurality of binding agents coupled to said graphene layer to generate a functionalized graphene layer, where the binding agents exhibit specific binding to at least one epitope of SARS-CoV-2 virus, and a plurality of electrical conductors electrically coupled to said functionalized graphene layer for measuring an electrical property (e.g., DC electrical resistance) of the functionalized graphene layer. While in some embodiments such binding agents are monoclonal antibodies, in other embodiments they can be polyclonal antibodies.Type: ApplicationFiled: March 22, 2021Publication date: September 23, 2021Inventors: Namal Nawana, Reza Mollaaghababa, Mehdi Abedi, Edward Alvin Greenfield, Nirva Patel, Mohammed Fotouhi
-
Publication number: 20210247409Abstract: In one aspect, a sensor for detecting hemoglobin protein (e.g., human hemoglobin protein) in a sample is disclosed, which includes a graphene layer, a plurality of binding agents coupled to said graphene layer to generate a functionalized graphene layer, where the binding agents exhibit specific binding to a hemoglobin protein (e.g., to human hemoglobin protein) and a plurality of electrical conductors electrically coupled to said functionalized graphene layer for measuring an electrical property (e.g., DC electrical resistance) of said functionalized graphene layer. While in some embodiments such binding agents are monoclonal antibodies, in other embodiments they can be polyclonal antibodies.Type: ApplicationFiled: February 8, 2021Publication date: August 12, 2021Inventors: Namal NAWANA, Mehdi Abedi, Reza Mollaaghababa
-
Publication number: 20210223271Abstract: In one aspect, a sensor for detecting a drug of abuse (DOA) in a sample is disclosed. In some embodiments, the sensor includes a graphene layer, a plurality of binding agents, which bind to the DOA, coupled to said graphene layer to generate a functionalized graphene layer, and a plurality of electrical conductors electrically coupled to said functionalized graphene layer for measuring an electrical property of said functionalized graphene layer. While in some embodiments, such binding agents are monoclonal antibodies, in other embodiments they are polyclonal antibodies.Type: ApplicationFiled: January 19, 2021Publication date: July 22, 2021Inventors: Namal Nawana, Mehdi Abedi, Reza Mollaaghababa
-
Publication number: 20210102937Abstract: A processing and detection system for detecting presence of at least one gluten protein in a food sample comprises a food processor including: a reservoir containing a process liquid for processing the food sample; a body that comprises a chamber configured to receive the food sample; and a pressing surface configured to press on the reservoir to cause the process liquid to exit the reservoir and mix with the food sample, thereby generating a processed food liquid; and an exit port configured to conduct the processed food liquid out of the food processor; and a cartridge including: at least one sensor configured to receive the processed food liquid and to generate an electrical signal in response to interaction with the at least one gluten protein in the processed food liquid, and an analyzer in electrical communication with the at least one sensor for detecting the electrical signal and determining the presence of the at least one gluten protein in the food sample based on the detected electrical signal.Type: ApplicationFiled: September 21, 2020Publication date: April 8, 2021Inventors: Mohammad E. Taslim, Mohammed Fotouhi, Mehdi Abedi, Reza Mollaaghababa, Bahram Fotouhi, Kashayar Javaherian, Edward Alvin Greenfield, Namal Nawana
-
Patent number: 10782285Abstract: A processing and detection system for detecting presence of at least one gluten protein in a food sample comprises a food processor including: a reservoir containing a process liquid for processing the food sample; a body that comprises a chamber configured to receive the food sample; and a pressing surface configured to press on the reservoir to cause the process liquid to exit the reservoir and mix with the food sample, thereby generating a processed food liquid; and an exit port configured to conduct the processed food liquid out of the food processor; and a cartridge including: at least one sensor configured to receive the processed food liquid and to generate an electrical signal in response to interaction with the at least one gluten protein in the processed food liquid, and an analyzer in electrical communication with the at least one sensor for detecting the electrical signal and determining the presence of the at least one gluten protein in the food sample based on the detected electrical signal.Type: GrantFiled: May 24, 2019Date of Patent: September 22, 2020Assignee: Rite Taste, LLCInventors: Mohammad E. Taslim, Mohammed Fotouhi, Mehdi Abedi, Reza Mollaaghababa, Bahram Fotouhi, Kashayar Javaherian, Edward Alvin Greenfield, Namal Nawana
-
Patent number: 10595844Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).Type: GrantFiled: July 26, 2018Date of Patent: March 24, 2020Assignee: DePuy Synthes Products, Inc.Inventors: Namal Nawana, William C. Horton, William J. Frasier, Cody Cranson, Max Reinhardt, Mark T. Hall, Matthew Parsons, Jennifer DiPietro, Kevin Lee, Michelle LaWare, John P. Griffin, Sean P. Selover, Jonathan Bellas, Douglas Raymond, Nicholas Pavento, Mary L. Fowler, Dennis Chien
-
Publication number: 20200011860Abstract: In one aspect, the present teachings provide a sensor for detecting troponin, e.g., cardiac troponin in a patient's blood, that relies on an electronic signature generated via interaction of troponin with an anti-troponin antibody. More specifically, as discussed in more detail below, such a sensor can include a graphene layer disposed on an underlying substrate, where the graphene layer has been functionalized with an anti-troponin antibody. The interaction of troponin in a sample, e.g., a patient's blood, with the anti-troponin antibody coupled, e.g., anchored, to the graphene substrate, can modulate an electronic property of the underlying graphene layer. The modulation of the electronic property of the graphene layer can be measured and used to identify, and in some embodiments quantify, troponin in the sample.Type: ApplicationFiled: May 24, 2019Publication date: January 9, 2020Inventors: Namal Nawana, Mohammad E. Taslim, Mohammed Fotouhi, Mehdi Abedi, Reza Mollaaghababa, Edward Alvin Greenfield
-
Publication number: 20190317081Abstract: A processing and detection system for detecting presence of at least one gluten protein in a food sample comprises a food processor including: a reservoir containing a process liquid for processing the food sample; a body that comprises a chamber configured to receive the food sample; and a pressing surface configured to press on the reservoir to cause the process liquid to exit the reservoir and mix with the food sample, thereby generating a processed food liquid; and an exit port configured to conduct the processed food liquid out of the food processor; and a cartridge including: at least one sensor configured to receive the processed food liquid and to generate an electrical signal in response to interaction with the at least one gluten protein in the processed food liquid, and an analyzer in electrical communication with the at least one sensor for detecting the electrical signal and determining the presence of the at least one gluten protein in the food sample based on the detected electrical signal.Type: ApplicationFiled: May 24, 2019Publication date: October 17, 2019Inventors: Mohammad E. Taslim, Mohammed Fotouhi, Mehdi Abedi, Reza Mollaaghababa, Bahram Fotouhi, Kashayar Javaherian, Edward Alvin Greenfield, Namal Nawana
-
Publication number: 20190284615Abstract: In one aspect, a method of detecting a pathogen, e.g., listeria bacterium, chlamydia bacteria, gonorrhea bacteria and/or HPV, in a sample is disclosed, which comprises bringing a sample into contact with a graphene layer functionalized with an antibody exhibiting specific binding to the pathogen, monitoring electrical resistance of said antibody-functionalized graphene layer in response to interaction with said sample, and detecting presence of the pathogen in said sample by detecting a change in said electrical resistance indicative of interaction of the pathogen with said antibody-functionalized graphene layer. For example, a decrease of the electrical resistance of the graphene layer can indicate the presence of the pathogen in the sample under study. In some embodiments, a method according to the present teachings is capable of detecting pathogens, such as listeria bacteria, chlamydia bacteria, gonorrhea bacteria and HPV in a sample at a concentration as low as 4 cfu per 100 grams of a sample.Type: ApplicationFiled: January 29, 2019Publication date: September 19, 2019Inventors: Mohammed Fotouhi, Mohammad E. Taslim, Mehdi Abedi, Edward Alvin Greenfield, Reza Mollaaghababa, Namal Nawana
-
Publication number: 20190216452Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).Type: ApplicationFiled: March 27, 2019Publication date: July 18, 2019Inventors: Namal Nawana, William C. Horton, William J. Frasier, Michael O'Neil, Robert E. Sommerich, Jennifer DiPietro, Matthew Parsons
-
Publication number: 20190110784Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).Type: ApplicationFiled: December 10, 2018Publication date: April 18, 2019Inventors: Namal Nawana, Michael Gorhan, William J. Frasier, William C. Horton, Mark T. Hall, Matthew Parsons, Jennifer DiPietro, Christopher Nordstrom
-
Publication number: 20190079068Abstract: Methods and devices for detecting a target agent of interest, e.g., a pathogen, in a sample are described herein. In some embodiments, a sensor is provided that can include a substrate, a graphene layer disposed on a surface of said substrate, and a protein bound to said graphene layer. The protein can be capable of binding to one or more target agents of interest, e.g., pathogens, etc. The binding of the protein to the one or more target agents of interest can generate a change in an electrical property of the graphene layer.Type: ApplicationFiled: July 26, 2018Publication date: March 14, 2019Inventors: Mohammad E. Taslim, Mohammed Fotouhi, Mehdi Abedi, Reza Mollaaghababa, Bahram Fotouhi, Kashayar Javaherian, Edward Alvin Greenfield, Namal Nawana
-
Patent number: 10166019Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, data related to retraction of tissue can be gathered during performance of a surgical procedure. In one embodiment, the data can be used during performance of the surgical procedure, e.g., to determine whether a length of time a tissue is retracted using a retractor reaches a predetermined threshold amount of time, an amount of tissue retraction reaches a predetermined amount of tissue, and an amount of pressure being placed on tissue and/or nerves as a result of retraction reaches a predetermined amount of pressure, and/or the data can be used after performance of the surgical procedure, e.g., in determining a correlation between the data and patient pain level data.Type: GrantFiled: June 9, 2015Date of Patent: January 1, 2019Assignee: DePuy Synthes Products, Inc.Inventors: Namal Nawana, Michael Gorhan, William J. Frasier, Cody Cranson, Hassan Serhan, Michael O'Neil, Matthew Parsons, Jennifer DiPietro, Christopher Nordstrom, John Griffin, Sean Selover, Jonathan Bellas, Michelle LeClerc
-
Publication number: 20180344309Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).Type: ApplicationFiled: July 26, 2018Publication date: December 6, 2018Inventors: Namal Nawana, William C. Horton, William J. Frasier, Cody Cranson, Max Reinhardt, Mark T. Hall, Matthew Parsons, Jennifer DiPietro, Douglas Raymond, James Paiva
-
Publication number: 20180344308Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).Type: ApplicationFiled: July 26, 2018Publication date: December 6, 2018Inventors: Namal Nawana, William C. Horton, William J. Frasier, Cody Cranson, Max Reinhardt, Mark T. Hall, Matthew Parsons, Jennifer DiPietro, Kevin Lee, Michelle LaWare, John P. Griffin, Sean P. Selover, Jonathan Bellas, Douglas Raymond, Nicholas Pavento, Mary L. Fowler, Dennis Chien
-
Publication number: 20180268923Abstract: Provided herein are new methods and systems to remotely administer toxicology tests while still preserving the chain of custody. These tea,methods and systems include ensuring that the tested samples originate from the subject and that the sample has not been adulterated. Ensuring that the tested samples originate from the subject and have not been adulterated is based on obtaining a first data of a first sample and comparing it to a second data of a second sample from the same subject.Type: ApplicationFiled: September 23, 2016Publication date: September 20, 2018Inventor: Namal NAWANA
-
Publication number: 20180030516Abstract: A method for determining data related to a microbiome of a human includes isothermally amplifying polynucleotides of at least N different microorganisms present in a sample obtained from the human, wherein N>1, determining, based on the amplified polynucleotides, microbiome data comprising data indicative of at least one of a presence and an abundance of each of the N microorganisms, and determining, based on the microbiome data and prior data related to the N microorganisms, data related to a condition of the animal.Type: ApplicationFiled: February 26, 2016Publication date: February 1, 2018Inventors: Namal Nawana, Julius C. Fister, III
-
Patent number: 9700292Abstract: Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s).Type: GrantFiled: May 20, 2015Date of Patent: July 11, 2017Assignee: DePuy Synthes Products, Inc.Inventors: Namal Nawana, William C. Horton, William J. Frasier, Hassan A. Serhan, Michael O'Neil, Robert E. Sommerich, Jennifer DiPietro, Christopher Nordstrom, Matthew Parsons, Thomas Martin