Patents by Inventor Nam-Joon Cho
Nam-Joon Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240158988Abstract: A pollen paper formed from a plurality of pollen microgels, which paper is dimensionally locked for use in the generation of conventional printed matter. It is possible to remove the printed subject matter from the pollen paper by a process that involves immersing the pollen paper into an alkaline bath, then removing the water through immersing it in a dehydrating bath and finally dimensionally locking the paper by immersing it in an acidic bath.Type: ApplicationFiled: March 16, 2022Publication date: May 16, 2024Inventors: Nam-Joon CHO, Ze ZHAO, Subra SURESH
-
Publication number: 20240150959Abstract: Disclosed herein is a hygromorphic composite material comprising a moisture-active pollen paper substrate formed from a plurality of pollen microgel particles, and at least one moisture-inactive layer applied onto the top and/or bottom surface of the moisture-active pollen paper substrate with a pattern that causes the hygromorphic composite material to change its shape in a pre-determined manner due to a change in relative humidity of its ambient environment. Also disclosed herein is a method of forming the hygromorphic composite material.Type: ApplicationFiled: March 16, 2022Publication date: May 9, 2024Inventors: Nam-Joon CHO, Ze ZHAO, Subra SURESH
-
Patent number: 11866460Abstract: Provided herein are anti-infective peptides and uses thereof. Such anti-infective peptides are useful against bacteria and viruses. Also provided herein are compositions comprising said anti-infective peptides.Type: GrantFiled: June 15, 2021Date of Patent: January 9, 2024Assignee: NANYANG TECHNOLOGICAL UNIVERSITYInventors: Nam-Joon Cho, Joshua Alexander Jackman
-
Publication number: 20220402972Abstract: Provided herein are anti-infective peptides and uses thereof. Such anti-infective peptides are useful against bacteria and viruses. Also provided herein are compositions comprising said anti-infective peptides.Type: ApplicationFiled: June 15, 2021Publication date: December 22, 2022Applicant: NANYANG TECHNOLOGICAL UNIVERSITYInventors: Nam-Joon Cho, Joshua Alexander Jackman
-
Patent number: 11498042Abstract: A new type of biomaterial that can be generated from pollen, methods for its production, the various uses thereof in, for example, biological, medicinal, cosmetic, nutritional and printing applications and the materials/devices that comprise this new material are provided. The biomaterial comprises microgels of sporoderm polymer complex microcapsules (SPC-MCs), produced by deproteinizing the pollen from eudicot plants, in particular of genus Baccharis, Helianthus or Camellia, by contacting it with an aqueous base solution at elevated temperatures for up to 10 hours to obtain porous SPC-MCs, and hydrolytically degrading the SPC-MCs by contacting it with an aqueous base solution for periods up to 60 days to obtain microgels of SPC-MCs.Type: GrantFiled: January 29, 2019Date of Patent: November 15, 2022Assignee: NANYANG TECHNOLOGICAL UNIVERSITYInventor: Nam-Joon Cho
-
Publication number: 20210346889Abstract: A microfluidic device is disclosed that is used to process cells for the intracellular delivery of molecules or other cargo. The device includes one or more microchannels disposed in a substrate or chip and is fluidically coupled to an inlet configured to receive a solution containing the cells and the molecules or other cargo to be delivered intracellularly to the cells. Each of the one or more microchannels has one or more constriction regions formed therein, wherein the inner surface(s) of the microchannels and the one or more constriction regions have a lipid bilayer disposed thereon. In some embodiments, multiple microfluidic devices operating in parallel are used to process large numbers of cells. The device and method have particularly applicability to delivering gene-editing molecules intracellularly to cells.Type: ApplicationFiled: August 21, 2019Publication date: November 11, 2021Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NANYANG TECHNOLOGICAL UNIVERSITYInventors: Jason N. Belling, Steven J. Jonas, Joshua A. A. Jackman, Nam-Joon Cho, Paul S. Weiss
-
Publication number: 20210077969Abstract: A new type of biomaterial that can be generated from pollen, methods for its production, the various uses thereof in, for example, biological, medicinal, cosmetic, nutritional and printing applications and the materials/devices that comprise this new material are provided. Said biomaterial comprises microgels of sporoderm polymer complex microcapsules (SPC-MCs), produced by deproteinizing the pollen from eudicot plants, in particular of genus Baccharis, Helianthus or Camellia, by contacting it with an aqueous base solution at elevated temperatures for up to 10 hours to obtain porous SPC-MCs, and hydrolytically degrading the SPC-MCs by contacting it with an aqueous base solution for periods up to 60 days to obtain microgels of SPC-MCs.Type: ApplicationFiled: January 29, 2019Publication date: March 18, 2021Inventor: Nam-Joon CHO
-
Patent number: 10787470Abstract: A method of preparing a solid-supported phospholipid bilayer is provided. The method includes a) a first step of providing a solution comprising a bicellar mixture of a long-chain phospholipid and a short-chain phospholipid; b) at least one second step of decreasing the temperature of the solution to below 0° C., increasing the temperature to above room temperature and causing the solution to be blended; and c) a third step of depositing the solution obtained after the second step on a surface of a support, wherein the concentration of the long-chain phospholipid in the solution is at most 0.1 mg/mL, for obtaining a solid-supported phospholipid bilayer. A solid-supported phospholipid layer obtained by the method as defined above is also provided.Type: GrantFiled: February 14, 2018Date of Patent: September 29, 2020Assignee: NANYANG TECHNOLOGICAL UNIVERSITYInventors: Nam-Joon Cho, Joshua Alexander Jackman
-
Patent number: 10752656Abstract: Supramolecular structures comprising noncovalently associated peptide amphiphiles and lipids are provided. In particular, provided herein are supramolecular nanostructures of peptide amphiphiles and lipids, co-assembly of which is driven by anion-? interactions, and methods of preparation and use (e.g., as an antimicrobial agent) thereof.Type: GrantFiled: October 20, 2017Date of Patent: August 25, 2020Assignees: Northwestern University, Nanyang Technological UnversityInventors: Samuel I. Stupp, Zhilin Yu, Nam-Joon Cho, Joshua A. Jackman
-
Publication number: 20200087349Abstract: Provided herein are anti-infective peptides and uses thereof. Such anti-infective peptides are useful against bacteria and viruses. Also provided herein are compositions comprising said anti-infective peptides.Type: ApplicationFiled: May 23, 2019Publication date: March 19, 2020Applicant: NANYANG TECHNOLOGICAL UNIVERSITYInventors: Nam-Joon Cho, Joshua Alexander Jackman
-
Publication number: 20200040017Abstract: A method of preparing a solid-supported phospholipid bilayer is provided. The method includes a) a first step of providing a solution comprising a bicellar mixture of a long-chain phospholipid and a short-chain phospholipid; b) at least one second step of decreasing the temperature of the solution to below 0° C., increasing the temperature to above room temperature and causing the solution to be blended; and c) a third step of depositing the solution obtained after the second step on a surface of a support, wherein the concentration of the long-chain phospholipid in the solution is at most 0.1 mg/mL, for obtaining a solid-supported phospholipid bilayer. A solid-supported phospholipid layer obtained by the method as defined above is also provided.Type: ApplicationFiled: February 14, 2018Publication date: February 6, 2020Inventors: Nam-Joon CHO, Joshua Alexander JACKMAN
-
Patent number: 10427124Abstract: The invention relates to a method of controlling adsorption of lipid molecules onto a solid support by tuning the steric-hydration force of the lipid vesicles and the surface of the solid support, such that the solid support either has a stabilized lipid bilayer adsorbed thereon or is resistant to adsorption of lipid molecules.Type: GrantFiled: September 19, 2014Date of Patent: October 1, 2019Assignee: Nanyang Technological UniversityInventors: Nam-Joon Cho, Joshua Alexander Jackman
-
Patent number: 10351604Abstract: Provided herein are anti-infective peptides and uses thereof. Such anti-infective peptides are useful against bacteria and viruses. Also provided herein are compositions comprising said anti-infective peptides.Type: GrantFiled: June 24, 2016Date of Patent: July 16, 2019Assignee: NANYANG TECHNOLOGICAL UNIVERSITYInventors: Nam-Joon Cho, Joshua Alexander Jackman
-
Patent number: 10203270Abstract: It is an object of the present invention to provide a measuring apparatus having a reduced size by a substitution of an optical measuring device. A measuring apparatus for measuring micro-fluid or floating particles therein according to an embodiment of the present invention includes: a micro-tube containing the micro-fluid; an actuator vibrating the micro-tube; and a tuning fork converting vibration of the micro-tube into an electrical signal.Type: GrantFiled: February 15, 2017Date of Patent: February 12, 2019Assignee: SOGANG UNIVERSITY RESEARCH FOUNDATIONInventors: Jungchul Lee, Donghyuk Lee, Sangken Kauh, Joonhui Kim, Nam-Joon Cho
-
Publication number: 20180186837Abstract: Provided herein are anti-infective peptides and uses thereof. Such anti-infective peptides are useful against bacteria and viruses. Also provided herein are compositions comprising said anti-infective peptides.Type: ApplicationFiled: June 24, 2016Publication date: July 5, 2018Applicant: NANYANG TECHNOLOGICAL UNIVERSITYInventors: Nam-Joon CHO, Joshua Alexander JACKMAN
-
Publication number: 20180111963Abstract: Supramolecular structures comprising noncovalently associated peptide amphiphiles and lipids are provided. In particular, provided herein are supramolecular nanostructures of peptide amphiphiles and lipids, co-assembly of which is driven by anion-n interactions, and methods of preparation and use (e.g., as an antimicrobial agent) thereof.Type: ApplicationFiled: October 20, 2017Publication date: April 26, 2018Inventors: Samuel I. Stupp, Zhilin Yu, Nam-Joon Cho, Joshua A. Jackman
-
Publication number: 20180003605Abstract: It is an object of the present invention to provide a measuring apparatus having a reduced size by a substitution of an optical measuring device. A measuring apparatus for measuring micro-fluid or floating particles therein according to an embodiment of the present invention includes: a micro-tube containing the micro-fluid; an actuator vibrating the micro-tube; and a tuning fork converting vibration of the micro-tube into an electrical signal.Type: ApplicationFiled: February 15, 2017Publication date: January 4, 2018Applicant: SOGANG UNIVERSITY RESEARCH FOUNDATIONInventors: Jungchul LEE, Donghyuk LEE, Sangken KAUH, Joonhui KIM, Nam-Joon CHO
-
Publication number: 20160334395Abstract: A method for forming a hydration layer/lipid bilayer structure on a solid support is provided. The method includes contacting a solution comprising at least one polar lipid and a water-miscible alcohol as a solvent with the solid support; and adding water to said solution at a predetermined rate, thus inducing formation of a hydration layer on the solid support surface and formation of a planar lipid bilayer on the hydration layer, wherein the hydration layer has an average thickness of at least 2 nm as well as the thus obtained solid supports with a hydration layer/lipid bilayer structure.Type: ApplicationFiled: January 21, 2015Publication date: November 17, 2016Inventors: Nam-Joon CHO, Seyed Ruhollah TABAEI AGHDA, Joshua Alexander JACKMAN
-
Publication number: 20160228839Abstract: The invention relates to a method of controlling adsorption of lipid molecules onto a solid support by tuning the steric-hydration force of the lipid vesicles and the surface of the solid support, such that the solid support either has a stabilized lipid bilayer adsorbed thereon or is resistant to adsorption of lipid molecules.Type: ApplicationFiled: September 19, 2014Publication date: August 11, 2016Inventors: Nam-Joon CHO, Joshua Alexander JACKMAN
-
Patent number: 8852614Abstract: Compositions and methods are provided for the manufacture and use of hydrogels with increased permeability to macromolecules with minimum loss of matrix mechanical strength and prepolymer viscosity for patternability. The hydrogels of the invention are formed from a prepolymer, which is polymerized in the presence of hydrophobic nanoparticles. In some embodiments of the invention cells are present during polymerization, and are encapsulated by the hydrogel. A high interfacial energy between the hydrophobic substrate and the aqueous polymerizing solution disrupts the hydrogel network structure, leading to network defects that increase permeability without loss of patternability.Type: GrantFiled: March 11, 2011Date of Patent: October 7, 2014Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Curtis W. Frank, Won Jae Lee, Nam-Joon Cho, Jeffrey S. Glenn