Abstract: The invention relates to methods of in situ detection of a nucleic acid variation of a target nucleic acid in a sample, including single nucleotide variations, multi-nucleotide variations or splice sites. The method can comprise the steps of contacting the sample with a probe that detects the nucleic acid variation or splice site and a neighbor probe; contacting the sample with pre-amplifiers that bind to the nucleic acid variation probe or splice site probe and neighbor probe, respectively; contacting the sample with a collaboration amplifier that binds to the pre-amplifiers; and contacting the sample with a label probe system, wherein hybridization of the components forms a signal generating complex (SGC) comprising a target nucleic acid with the nucleic acid variation or splice site, the probes and amplifiers; and detecting in situ signal from the SGC on the sample.

Abstract: A light-adjusting film is mounted between a color conversion layer and a display panel of a direct type backlight module and has a substrate and at least one light-adjusting layer. The substrate has a central area and a surrounding area. The at least one light-adjusting layer has a pigment and is mounted on the substrate. A content of the pigment is gradually decreased from the surrounding area to the central area. The color of the pigment of the light-adjusting film is a correction color of lights emitted from light emitting surface of the color conversion layer in the backlight module.

Abstract: Disclosed is an Andrias davidianus cartilage preparation. The Andrias davidianus cartilage enzymatic extract of the present invention is obtained by a method comprising: obtaining cartilage from Andrias davidianus, proteolyzing the obtained cartilage, obtaining a supernatant after the proteolysis, and drying the supernatant. The Andrias davidianus cartilage enzymatic extract and an alcohol-soluble component thereof according to the present invention comprise a cartilage polypeptide, and have the effects of lowering uric acid, or treating hyperuricemia.

Abstract: The present invention relates to detection of nucleic acids and provides a composition comprising a Signal Generating Complex, wherein the composition comprises: (A) a pair of target probes (TPs), wherein a first TP of the pair of TPs comprises a nucleic acid sequence comprising two segments; (B) a pair of base PPAs comprising the first and second base PPAs, wherein the first base PPA comprises a nucleic acid sequence comprising three segments; (C) a set of extension PPAs comprising the first and second extension PPAs, wherein the first extension PPA comprises a nucleic acid sequence comprising two segments; (D) a plurality of pre-amplifiers (PAs), wherein the PAs comprise a nucleic acid sequence comprising three segments; (E) a plurality of amplifiers (AMPs), wherein the AMPs comprise a nucleic acid sequence comprising two segments; and (F) a plurality of label probes (LPs), wherein the LPs comprise a nucleic acid sequence comprising two segments.

Abstract: A light-adjusting film is mounted between a color conversion layer and a display panel of a direct type backlight module and has a substrate and at least one light-adjusting layer. The substrate has a central area and a surrounding area. The at least one light-adjusting layer has a pigment and is mounted on the substrate. A content of the pigment is gradually decreased from the surrounding area to the central area. The color of the pigment of the light-adjusting film is a correction color of lights emitted from light emitting surface of the color conversion layer in the backlight module.

Abstract: A keyboard with a vibration function is provided. The keyboard includes a base member, an upper cover, a basic key structure and a vibration key structure. The vibration key structure includes a control module, a vibration keycap and an isolation element. The control module is fixed on the upper cover. When the control module is triggered, a vibration key signal is generated and a vibration action is provided. The control module is covered by the vibration keycap. The vibration keycap is exposed outside the upper cover. The isolation element is arranged between the control module and the upper cover. The vibration key structure is enclosed by the isolation element, so that the energy of the vibration action from the control module is isolated.

Abstract: The invention relates to methods of detecting nucleic acids, including methods of detecting one or more target nucleic acid sequences in multiplex branched-chain DNA assays, are provided. Nucleic acids captured on a solid support or suspending cells are detected, for example, through cooperative hybridization events that result in specific association of a label with the nucleic acids. The invention further relates to methods to improve probe hybridization specificity and their application in genotyping. The invention also relates to in situ detection of mis-joined nucleic acid sequences. The invention relates to reducing false positive signals and improve signal-to-background ratio in hybridization-based nucleic acid detection assay. The invention further relates to method to improve specificity in hybridization based nucleic acid using co-location probes. Compositions, tissue slides, sample of suspended cells, kits, and systems related to the methods are also described.

Abstract: A roller module for an input module includes a roller base, a roller element and an adjusting element. The roller element is pivotally coupled to the roller base. Moreover, at least one discontinuous protrusion structure is circumferentially arranged a bottom surface of a concave region of the roller element. A contacting part of the adjusting element is contacted with the at least one discontinuous protrusion structure. Consequently, a rotation of the roller element results in a tactile feel.

Abstract: A mouse device includes a main body, an air cushion and a first hidden key. The first hidden key is located at a first side of the main body. The air cushion is located under the main body, and contactable with a working surface. The first hidden key is arranged between the main body and the air cushion. The first hidden key is not exposed outside. When the main body is leaned in a first direction and pressed down, the first hidden key is triggered to generate a first leaning signal. The first hidden key can be used to replace the key of the conventional keyboard. Due to the structure of the mouse device, the mouse device can be operated more intuitively.

Abstract: A keyboard device for a computing device is provided. The computing device includes a first system module and a second system module. The keyboard device includes a keyboard module and at least two conductive sliding mechanisms. The keyboard module is installed on the first system module. The keyboard module includes a power supply unit. The power supply unit provides electric power for powering the keyboard module. The keyboard module is movable relative to the first system module through the conductive sliding mechanisms. Each conductive sliding mechanism includes a sliding base and a conductive member. The sliding base is installed on the keyboard module. The conductive member is electrically connected with the first system module and the keyboard module. When the sliding base is moved relative to the conductive member, the keyboard module is moved relative to the first system module.

Abstract: A keyboard device for a computing device is provided. The computing device includes a first system module and a second system module. The keyboard device includes a keyboard module and at least two conductive sliding mechanisms. The keyboard module is installed on the first system module. The keyboard module includes a power supply unit. The power supply unit provides electric power for powering the keyboard module. The keyboard module is movable relative to the first system module through the conductive sliding mechanisms. Each conductive sliding mechanism includes a sliding base and a conductive member. The sliding base is installed on the keyboard module. The conductive member is electrically connected with the first system module and the keyboard module. When the sliding base is moved relative to the conductive member, the keyboard module is moved relative to the first system module.

Abstract: A roller module for an input module includes a roller base, a roller element and an adjusting element. The roller element is pivotally coupled to the roller base. Moreover, at least one discontinuous protrusion structure is circumferentially arranged a bottom surface of a concave region of the roller element. A contacting part of the adjusting element is contacted with the at least one discontinuous protrusion structure. Consequently, a rotation of the roller element results in a tactile feel.

Abstract: The present invention provides a mouse with a low friction roller module, including a mouse body and a low friction roller module; the low friction roller module is mounted in the mouse body and includes a support, a roller, a low friction bearing, a support shaft, and an encoding component; a mounting portion is provided in the roller; the low friction bearing is fastened in the mounting portion; one side of the support shaft passes through and is connected to the low friction bearing, and the other side of the support shaft passes through and is connected to the support; and the encoding component is connected to the roller. In this way, rolling friction force is reduced.

Abstract: The present invention provides an antenna structure, including a radiation component, a short-circuit pin, a metal matching component, and a signal feed-in component, where the radiation component is disposed above a circuit board, two ends of the short-circuit pin are separately connected to the radiation component and a ground end that is on the circuit board, the metal matching component is disposed on the circuit board and is configured to change impedance of the antenna structure, two ends of the signal feed-in component are separately connected to the radiation component and the metal matching component, and a current from the circuit board sequentially flows through the metal matching component and the signal feed-in component before arriving at the radiation component, so that the radiation component transmits a radiation signal. In addition, the present invention further provides a circuit module and an electronic device using the antenna structure.

Abstract: A mask transmission equipment is provided. The mask transmission equipment includes a wafer transmission container and a supporting bracket. The wafer transmission container includes a plurality of first positioning grooves and a plurality of second positioning grooves. The first positioning grooves face the second positioning grooves. The first positioning grooves and the second positioning grooves are adapted to position a plurality of wafers. The supporting bracket is disposed in the wafer transmission container. The supporting bracket includes a first supporting unit, a second supporting unit, a first wing and a second wing. The first supporting unit is stacked on the second supporting unit. The first wing is disposed on a first side of the supporting bracket. The second wing is disposed on a second side of the supporting bracket. The first side is opposite to the second side.

Abstract: The present invention provides a mouse with an electromagnetic module, including: a mouse body, a scroll wheel and an electromagnetic module. The scroll wheel is mounted in the mouse body, and the scroll wheel is provided with a mounting area. The electromagnetic module is mounted in the mouse body. The electromagnetic module includes: a metal inner ratchet, a connecting piece, an electromagnet, and a control element. The metal inner ratchet is fastened in the mounting area. The connecting piece includes a connecting section and a free section. The connecting section is connected to the mouse body, and the free section passes through the mounting area. The electromagnet is mounted on the free section. The control element is electrically connected to the electromagnet. In this way, an effect of continuous-ratcheting is achieved.

Abstract: The present invention provides a mouse with a soundless scroll wheel module, including a mouse body and a soundless scroll wheel module. The soundless scroll wheel module includes a supporting frame, a scroll wheel body, a mute inner ratchet wheel, a strut, an elastic component, and an encoding component. The mute inner ratchet wheel is installed in the scroll wheel body. The strut includes an engagement segment and the engagement segment is engaged with the mute inner ratchet wheel. The mute inner ratchet wheel comprises a flexible annular body and multiple flexible ratchets for reducing rolling noise.

Abstract: A mouse device includes a main body, an air cushion and a first hidden key. The first hidden key is located at a first side of the main body. The air cushion is located under the main body, and contactable with a working surface. The first hidden key is arranged between the main body and the air cushion. The first hidden key is not exposed outside. When the main body is leaned in a first direction and pressed down, the first hidden key is triggered to generate a first leaning signal. The first hidden key can be used to replace the key of the conventional keyboard. Due to the structure of the mouse device, the mouse device can be operated more intuitively.

Abstract: A mask transmission equipment is provided. The mask transmission equipment includes a wafer transmission container and a supporting bracket. The wafer transmission container includes a plurality of first positioning grooves and a plurality of second positioning grooves. The first positioning grooves face the second positioning grooves. The first positioning grooves and the second positioning grooves are adapted to position a plurality of wafers. The supporting bracket is disposed in the wafer transmission container. The supporting bracket includes a first supporting unit, a second supporting unit, a first wing and a second wing. The first supporting unit is stacked on the second supporting unit. The first wing is disposed on a first side of the supporting bracket. The second wing is disposed on a second side of the supporting bracket. The first side is opposite to the second side.

Abstract: The present invention provides a mouse with an electromagnetic module, including: a mouse body, a scroll wheel and an electromagnetic module. The scroll wheel is mounted in the mouse body, and the scroll wheel is provided with a mounting area. The electromagnetic module is mounted in the mouse body. The electromagnetic module includes: a metal inner ratchet, a connecting piece, an electromagnet, and a control element. The metal inner ratchet is fastened in the mounting area. The connecting piece includes a connecting section and a free section. The connecting section is connected to the mouse body, and the free section passes through the mounting area. The electromagnet is mounted on the free section. The control element is electrically connected to the electromagnet. In this way, an effect of continuous-ratcheting is achieved.