Abstract: Disclosed herein are heterocyclic compounds, for example, according to the following formula and analogs thereof: that inhibit the activity of FLT3. Also described are specific covalent inhibitors of FLT3. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the FLT3 inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of proliferative diseases or conditions, including hematological malignancies and other diseases or conditions dependent on FLT3 activity.

Abstract: A speech processing method, performed by an electronic device, includes determining a first speech feature and a first text bottleneck feature based on to-be-processed speech information, determining a first combined feature vector based on the first speech feature and the first text bottleneck feature, inputting the first combined feature vector to a trained unidirectional long short-term memory (LSTM) model, performing speech processing on the first combined feature vector to obtain speech information after noise reduction, and transmitting the obtained speech information after noise reduction to another electronic device for playing.

Abstract: In embodiments of the present disclosure, there is provided an approach for fact checking based on semantic graphs. According to embodiments of the present disclosure, after obtaining a text to be fact checked, a plurality of evidence sentences related to the text are retrieved from an evidence database. Then, semantic graphs of the text and the evidence sentences are constructed based on the semantic analysis, and a veracity of a statement in the text can be determined based on the semantic graphs. Embodiments of the present disclosure propose a graph-based reasoning approach for fact checking, and use the constructed semantic graphs to facilitate verification of the truthfulness of the text, thereby improving the accuracy for fact checking.

Abstract: An electronic device has a keyboard with an internal membrane. The membrane has a set of strain gauges configured to respond to a key press, such as when a collapsible dome collapses into contact with the membrane. The strain gauges are connected in a half Wheatstone bridge configuration and are positioned on the membrane in order to limit effects of temperature and subtle flexure of the membrane. The strain gauges are also configured to magnify detection of a resistance differential when a keycap is pressed with sufficient force.

Abstract: An acute kidney injury predicting system and a method thereof are proposed. A processor reads the data to be tested, the detection data, the machine learning algorithm and the risk probability comparison table from a main memory. The processor trains the detection data according to the machine learning algorithm to generate an acute kidney injury prediction model, and inputs the data to be tested into the acute kidney injury prediction model to generate an acute kidney injury characteristic risk probability and a data sequence table. The data sequence table lists the data to be tested in sequence according to a proportion of each of the data to be tested in the acute kidney injury characteristics. The processor selects one of the medical treatment data from the risk probability comparison table according to the acute kidney injury characteristic risk probability.

Abstract: A wireless power transmitter can include a wireless power transfer coil designed to magnetically couple with a corresponding coil in a wireless power receiver to facilitate wireless power transfer from the wireless power transmitter to the wireless power receiver, a power converter configured to drive the wireless power transfer coil, and control and communications circuitry coupled to the wireless power transfer coil and the power converter. The control and communications circuitry can be configured to operate the power converter to drive the wireless power transfer coil so as to transfer power to the wireless power receiver in accordance with a negotiated power transfer. Simultaneously during power transfer, the control and communications circuitry can send a polling signal to detect a foreign object including a wireless transponder and reduce or stop wireless power transfer upon receiving a response to the polling signal from a foreign object including a wireless transponder.

Abstract: A high-efficiency yield-increasing exploitation method for natural gas hydrates includes steps of drilling of natural gas hydrate reservoirs along horizontal wells, seepage increasing by fracturing for fracture forming and stability improvement by grouting in the natural gas hydrate reservoirs, and yield improvement by combined exploitation of depressurization of the horizontal wells and heat injection; according to the present invention, drilling time is shortened by rapid drilling along the horizontal wells, the permeability of the reservoirs can be effectively improved by fracturing for fracture forming, the stability of the reservoirs can be improved by injecting by the combined exploitation method of depressurization of the horizontal wells and heat injection.

Abstract: A container conveying system including a controller, a first robot, and/or a second robot. A first container pickup mechanism is provided on the first robot. A second container pickup mechanism is provided on the second robot. The controller is configured to, in response to a container conveying request, send a first conveying instruction to the first robot if it is determined a target container to be conveyed based on the container conveying request has a size within a first size range; or send a second conveying instruction to the second robot if it is determined the target has a size within a second size range. In warehousing operation scenarios, by jointly using the two robots for operation, containers with various container sizes can be picked up and placed, thus improving utilization rate of a container storage space.

Abstract: A method of forming an IC structure includes forming first and second power rails at a power rail level. First metal segments are formed at a first metal level above the power rail level. Each first metal segment of the plurality of first metal segments overlap one or both of the first power rail or the second power rail. First vias are formed between the power rail level and the first metal level. Second metal segments are formed at a second metal level above the first metal level. At least one second metal segment of the plurality of second metal segments overlaps the first power rail. At least one second metal segment of the plurality of second metal segments overlaps the second power rail. A plurality of second vias are formed between the first metal level and the second metal level.

Abstract: A logic cell structure includes a first portion, a second portion and a third portion. The first portion, arranged to be a first layout of a first semiconductor element, is placed in a first cell row of a substrate area extending in a first direction. The second portion, arranged to be a second layout of a second semiconductor element, is placed in a second cell row of the substrate area. The third portion is arranged to be a third layout of an interconnecting path used for coupling the first semiconductor element and the second semiconductor element. The first, second and third portions are bounded by a bounding box with a height in a second direction and a width in the first direction. Respective centers of the first portion and the second portion are arranged in a third direction different from each of the first direction and the second direction.

Abstract: The application proposes a non-destructive testing method for the sealing degree of the small cigarette box packaging, which includes placing the small cigarette box to be tested in an airtight chamber, using a balance cabin to quickly form a stable negative pressure in the airtight chamber; The pressure change of the sealed chamber is continuously measured until equilibrium, and the data model is analyzed and established by using Darcy's law, Fick's diffusion law and the physical process of molecular kinetic theory. Through the non-destructive testing method for the sealing degree of the small cigarette box packaging of the present invention, the traditional destructive measurement (damaged small box packaging) for measuring the sealing degree of cigarette small box is changed into non-destructive testing; The test results have specific physical meaning; The test time of a single sample is reduced to ? of the time of destructive test.

Abstract: The present disclosure provides a routing structure. The routing structure includes a substrate having a boundary and a first conductive trace configured to be coupled to a first conductive pad disposed within the boundary of the substrate. The first conductive trace is inclined with respect to the boundary of the substrate.

Abstract: A method of characterizing an effect of a compound on cardiomyocyte beating, including providing a system configured to culture, electrically pace, and monitor heating of beating cells: culturing two populations of immature cardiomyocytes in the system; adding a compound suspected of having an effect on cardiomyocyte maturation to one of the populations of immature cardiomyocytes; electrically pacing the two populations of immature cardiomyocytes according to a pulse profile that functionally matures immature cardiomyocytes until at least one of the two populations of cardiomyocytes is functionally mature; and Characterizing the compound as further driving maturation if the population with compound addition functionally matures before the other cardiomyocyte population.

Abstract: A method of manufacturing a positive electrode material has the steps of synthesizing an iron metal in a phosphoric acid solution to form an iron phosphate dispersion solution; adding a vanadium pentoxide (V2O5), a non-ionic surfactant and a carbon source to the iron phosphate dispersion solution; and adding a lithium salt to the iron phosphate dispersion solution and then grinding and dispersing it to produce a positive electrode material. By regulating the timing of the addition of vanadium pentoxide (V2O5), the present invention enables the battery made of the positive electrode material to have the advantage of higher battery performance.

Abstract: There is provided a smoke detector including a first light source, a second light source surface, a light sensor and a processor. The light sensor receives reflected light when the first light source and the second light source emit light, and generates a first detection signal corresponding to light emission of the first light source and a second detection signal corresponding to light emission of the second light source. The processor distinguishes smoke and floating particles according to a similarity between the first detection signal and the second detection signal.

Abstract: A method includes acquiring multiple pieces of first received signal quality information at a receiver, where the multiple pieces of first received signal quality information represent qualities of signals received at the receiver, generating first conditional sample statistical values based on the multiple pieces of first received signal quality information and phase shift arrays corresponding to the signals, determining the first phase shift array that meets a communication requirement according to the first conditional sample statistical values, where the first phase shift array includes the phase shift value for at least one reflective element of an IRS, and configuring the IRS based on the first phase shift array.

Abstract: Semiconductor structures and methods for forming the same are provided. A method according to the present disclosure includes forming active regions on a substrate, forming an interconnect structure over the active regions, the interconnect structure including a plurality of dielectric layers and a guard ring disposed within the dielectric layers, etching an opening through the interconnect structure and at least a first portion of the active regions, the opening extending into the substrate, and forming a via structure within the opening. The via structure is surrounded by the guard ring when viewed along a direction perpendicular to a top surface of the substrate.

Abstract: A low-oxygen heating-type cigarette assembly, comprising a low-oxygen heating-type smoking set (B) and a low-oxygen heating-type cigarette (A). The low-oxygen heating-type smoking set (B) comprises a heating section (4) and a smoke extracting member (2) detachably arranged with the heating section (4), wherein the heating section (4) is provided with a cigarette receiving chamber (4-1), and the smoke extracting member (2) comprises a hollow smoke extracting cone (2-1) and a smoke transmission tube (2-2).

Abstract: Provided are method and system of calculating cross-section area and included angle of three-dimensional blood vessel branch, comprising: obtaining the contours of a main blood vessel and a branch blood vessel; determining connecting points of the main blood vessel and the branch blood vessel, a three-dimensional branch outer contour, and an initial normal vector of a branch section; determining the position of the branch section at the branch connecting part and an intersecting cross-section of the branch section and the branch outer contour; rotating the three-dimensional branch cross-section contour to obtain an equivalent two-dimensional branch cross-section contour, and calculating the area of the two-dimensional branch cross-section contour; obtaining branch cross-section areas and corresponding normal vectors thereof; and taking the minimum branch cross-section area as the cross-section area of this segment of branch blood vessel, and determining the included angle between the branch blood vessel and t

Abstract: A CNS millbase dispersion, comprises a solvent and up to 0.5 wt % of at least one CNS-derived material dispersed in the millbase dispersion and selected from the group consisting of: carbon nanostructures, fragments of carbon nanostructures, fractured carbon nanotubes, and any combination thereof. The carbon nanostructures or fragments of carbon nanostructures include a plurality of multiwall carbon nanotubes that are crosslinked in a polymeric structure by being branched, interdigitated, entangled and/or sharing common walls, and the fractured carbon nanotubes are derived from the carbon nanostructures and are branched and share common walls with one another. A Brookfield viscosity of the dispersion measured at room temperature at 10 rpm is less than 3000 cP.