Patents by Inventor Nancy Amelia Black

Nancy Amelia Black has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HCO32 and HCO27 and related examples
    Patent number: 9693539
    Abstract: The instant invention relates to transgenic non-human animals capable of producing heterologous antibodies, transgenes used to produce such transgenic animals, transgenes capable of functionally rearranging a heterologous D gene in V-D-J recombination, immortalized B-cells capable of producing heterologous antibodies, methods and transgenes for producing heterologous antibodies of multiple isotypes, methods and transgenes for producing heterologous antibodies wherein a variable region sequence comprises somatic mutation as compared to germline rearranged variable region sequences, transgenic nonhuman animals which produce antibodies having a human primary sequence and which bind to human antigens, hybridomas made from B cells of such transgenic animals, and monoclonal antibodies expressed by such hybridomas.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: July 4, 2017
    Assignee: E. R. SQUIBB & SONS, L.L.C.
    Inventors: Daniel K. Rohrer, Nancy Amelia Black, Nils Lonberg
  • HCO32 AND HCO27 AND RELATED EXAMPLES
    Publication number: 20120047585
    Abstract: The instant invention relates to transgenic non-human animals capable of producing heterologous antibodies, transgenes used to produce such transgenic animals, transgenes capable of functionally rearranging a heterologous D gene in V-D-J recombination, immortalized B-cells capable of producing heterologous antibodies, methods and transgenes for producing heterologous antibodies of multiple isotypes, methods and transgenes for producing heterologous antibodies wherein a variable region sequence comprises somatic mutation as compared to germline rearranged variable region sequences, transgenic nonhuman animals which produce antibodies having a human primary sequence and which bind to human antigens, hybridomas made from B cells of such transgenic animals, and monoclonal antibodies expressed by such hybridomas.
    Type: Application
    Filed: August 8, 2008
    Publication date: February 23, 2012
    Applicant: Medarex, Inc.
    Inventors: Daniel K. Rohrer, Nancy Amelia Black, Nils Lonberg