Patents by Inventor Nancy Dos Santos

Nancy Dos Santos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles
    Patent number: 6835395
    Abstract: Lipidic compositions with superior characteristics for in vivo delivery of oligodeoxynucleotides (ODN) can easily and efficiently be made in the form of small multilamellar vesicles. The compositions contain a population of nucleic acid-containing lipid vesicles in a liquid carrier, and at least a portion of the lipid vesicles are small multilamellar vesicles. The small multilamellar vesicles are made from a lipid component including 20-30 mol % of an ionizable amino lipid such as DODAP, and a steric barrier lipid such as PEG-CerC14; and an oligodeoxynucleotide contained in the lumen or interlamellar spaces of the small multilamellar vesicles. The ODN and lipid components are preferably present in the small multilamellar vesicles in a mole ratio of from 0.15 to 0.25.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: December 28, 2004
    Assignee: The University of British Columbia
    Inventors: Sean C. Semple, Sandra K. Klimuk, Troy O. Harasym, Nancy Dos Santos, Steven M. Ansell, Pieter R Cullis, Michael J. Hope, Peter Scherrer, Deirdre McIntosh, Kim F. Wong, Norbert Maurer