Abstract: The wound dressing securement device has one or more flexible adhesive base member strips that are secured to the skin around or at opposite sides of a wound with sufficient clearance for a wound dressing. A plurality of sheet retention members joined to one or more of the base members project vertically from an exposed surface of the base member. A flexible, foldable, stretchable hold-down sheet member has a plurality of openings to engage with engagement heads provided on the sheet retention members. The hold-down sheet member is sized to form a cover for the underlying wound dressing and bears against the wound dressing to hold it in position on the wound. When the wound dressing is to be changed, the hold-down sheet member is disengaged from the sheet retention members to uncover the wound dressing, and make it accessible for removal and replacement. The adhesive base member(s) remain in place during repeated changes of the wound dressing.