Patents by Inventor Nancy Jane Levin

Nancy Jane Levin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-diabetic compounds
    Patent number: 9163227
    Abstract: The present invention provides a composition of the formula: [FGF21-1st Linker]-[Ab]-[2nd-Linker-Ex4]; wherein FGF21 is an FGF21 homologue; and Ex4 is an Exendin4 homologue; and Ab is an aldolase catalytic antibody or antigen binding portion thereof; and the 1st linker is covalently attached to the side chain of a protein-linking residue in FGF21 and to a combining site of the antibody, and the 2nd linker is covalently attached to the side chain of a peptide-linking residue in Ex4 and to a combining site of the antibody, and wherein the first and second linker are the same or different. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: October 20, 2015
    Assignee: COVX TECHNOLOGIES IRELAND LIMITED
    Inventors: Gopinath Vedachalam Annathur, Palani Balu, Rory Francis Finn, Jie Huang, Olivier Alexandre Laurent, Nancy Jane Levin, Nicholas Gary Luksha, Joseph Patrick Martin, Jr., Haim Moskowitz, Moorthy Sitharamaiah Suriyanarayana Palanki, Mark John Pozzo, Gregory Allan Waszak, Jin Xie
  • FGF21 conjugates and anti-diabetic uses thereof
    Patent number: 8722622
    Abstract: The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: May 13, 2014
    Assignees: COVX Technologies Ireland, Limited, Pfizer Inc.
    Inventors: Tapan Kanti Das, Tamara Shafer Hodge, Tetsuya Ishino, Nancy Jane Levin, Moorthy Sitharamaiah Suriyanarayana Palanki, Erin Kristen Parsons, Bernard Norman Violand
  • Anti-Diabetic Compounds
    Publication number: 20120282279
    Abstract: The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
    Type: Application
    Filed: November 4, 2011
    Publication date: November 8, 2012
    Applicants: COVX TECHNOLOGIES IRELAND LIMITED, PFIZER INC
    Inventors: Tapan Kanti Das, Tamara Shafer Hodge, Tetsuya Ishino, Nancy Jane Levin, Moorthy Sitharamaiah Suriyanarayana Palanki, Erin Kristan Parsons, Bernard Norman Violand