Patents by Inventor Nangnoy Chuaymung

Nangnoy Chuaymung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BACTERIAL SURROGATE FOR TESTING OF ANTIMALARIALS: thyA KNOCKOUT AND folA KNOCKOUT BACTERIA FOR TESTING OF INHIBITION OF MALARIAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE
    Publication number: 20140295478
    Abstract: The objective of this invention is to create a double thyA folA knockout Escherichia coli (E. coli) strain for antifolate screening against DHFR of malaria and other parasites. This strain is used together with a plasmid expressing DHFR-TS from the desired pathogenic organism, which constitutes an anti-DHFR assay against the pathogenic organism of interest. The benefit of this invention is that there is no interference from either host DHFR or trimethoprim, a bacterial DHFR inhibitor. This tool is easy to use and maintain. It provides quick and reliable results as compared with conventional anti-malarial and anti-parasitic assays. This invention should facilitate discovery of new anti-DHFR compounds against malaria and other parasitic diseases.
    Type: Application
    Filed: February 9, 2012
    Publication date: October 2, 2014
    Applicant: National Science and Technology Development Agency
    Inventor: Nangnoy Chuaymung