Patents by Inventor Naohisa Ogo

Naohisa Ogo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDO/TDO Inhibitor
    Publication number: 20220380305
    Abstract: A compound of formula (I) given below or a pharmaceutically acceptable salt of the compound is useful as an IDO/TDO inhibitor.
    Type: Application
    Filed: July 11, 2022
    Publication date: December 1, 2022
    Inventors: Akira Asai, Naohisa Ogo, Daisuke Muraoka, Osamu Takikawa, Takumi Kawabe, Takuji Sato, Hisashi Murakami
  • IMMUNE CHECKPOINT INHIBITOR COMBINATION THERAPY USING QUINOLINE CARBOXAMIDE DERIVATIVE
    Publication number: 20220218693
    Abstract: Provided is a method for using a STAT3 inhibitor which exhibits an excellent antitumor effect. An antitumor agent comprises a quinoline carboxamide derivative of formula (I) below or a salt thereof as an active ingredient, and is administered in combination with an immune checkpoint inhibitor. The antitumor agent is administered before the administration of the immune checkpoint inhibitor.
    Type: Application
    Filed: April 23, 2020
    Publication date: July 14, 2022
    Applicants: KABUSHIKI KAISHA YAKULT HONSHA, GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION
    Inventors: Akira ASAI, Nao MIYOSHI, Daisuke MURAOKA, Naohisa OGO, Hiroyuki TAKAHASHI
  • Agent for overcoming immunosuppression and use thereof
    Patent number: 11213538
    Abstract: To provide an agent for overcoming immunosuppression which can overcome immunosuppression by regulatory T cells. An agent for overcoming immunosuppression and an inhibitor of FOXP3 function containing an anthracycline antibiotic as an active ingredient.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: January 4, 2022
    Assignees: GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION, KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Akira Asai, Naohisa Ogo, Daisuke Muraoka, Hiroshi Shiku, Naozumi Harada
  • Anti-norovirus composition and utilization thereof
    Patent number: 11020371
    Abstract: Provided are: a composition having an excellent anti-norovirus effect; use of a theaflavin compound for the preparation of the composition; and a method for preventing infection with a norovirus using a theaflavin compound. A theaflavin compound is used as an active ingredient for preventing infection with a norovirus. The theaflavin compound is preferably used together with an alcohol. The theaflavin compound is preferably one or more members selected from the group consisting of theaflavin, theaflavin-3-O-gallate, theaflavin-3?-O-gallate and theaflavin-3,3?-O-digallate that are derived from tea components.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: June 1, 2021
    Assignees: YAIZU SUISANKAGAKU INDUSTRY CO., LTD., GENERAL INCORPORATED ASSOCIATION PHARMAVALLEY PROJECT SUPPORTING ORGANIZATION
    Inventors: Mai Ohba, Takayuki Ando, Akira Asai, Naohisa Ogo
  • IDO/TDO Inhibitor
    Publication number: 20200239452
    Abstract: A compound of formula (I) given below or a pharmaceutically acceptable salt of the compound is useful as an IDO/TDO inhibitor.
    Type: Application
    Filed: October 17, 2018
    Publication date: July 30, 2020
    Inventors: Akira Asai, Naohisa Ogo, Daisuke Muraoka, Osamu Takikawa, Takumi Kawabe, Takuji Sato
  • AGENT FOR OVERCOMING IMMUNOSUPPRESSION AND USE THEREOF
    Publication number: 20190038645
    Abstract: To provide an agent for overcoming immunosuppression which can overcome immunosuppression by regulatory T cells. An agent for overcoming immunosuppression and an inhibitor of FOXP3 function containing an anthracycline antibiotic as an active ingredient.
    Type: Application
    Filed: February 15, 2017
    Publication date: February 7, 2019
    Applicants: GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION, KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Akira ASAI, Naohisa OGO, Daisuke MURAOKA, Hiroshi SHIKU, Naozumi HARADA
  • ANTI-NOROVIRUS COMPOSITION AND UTILIZATION THEREOF
    Publication number: 20190000796
    Abstract: Provided are: a composition having an excellent anti-norovirus effect; use of a theaflavin compound for the preparation of the composition; and a method for preventing infection with a norovirus using a theaflavin compound. A theaflavin compound is used as an active ingredient for preventing infection with a norovirus. The theaflavin compound is preferably used together with an alcohol. The theaflavin compound is preferably one or more members selected from the group consisting of theaflavin, theaflavin-3-O-gallate, theaflavin-3?-O-gallate and theaflavin-3,3?-O-digallate that are derived from tea components.
    Type: Application
    Filed: December 20, 2016
    Publication date: January 3, 2019
    Applicants: YAIZU SUISANKAGAKU INDUSTRY CO., LTD., GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PRO JECT SUPPORTING ORGANIZATION
    Inventors: Mai OHBA, Takayuki ANDO, Akira ASAI, Naohisa OGO
  • 1,3,4-Oxadiazole-2-carboxamide compound
    Patent number: 8796320
    Abstract: Provided is a 1,3,4-oxadiazole-2-carboxamide compound which has STAT3 inhibitory activity and is useful as an anticancer agent. Provided is a 1,3,4-oxadiazole-2-carboxamide compound represented by formula (I) or a pharmacologically acceptable salt thereof (in the formula, Ar represents a furyl group or the like; R1 represents a hydrogen atom or the like; and —X—Y represents a diaryl group such as a biphenyl group).
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: August 5, 2014
    Assignees: General Incorporated Association Pharma Valley Project Supporting Organization, Pharma Design, Shizuoka Prefecture, Kumamoto Health Science University, Kabushiki Kaisha Yakult Honsha
    Inventors: Akira Asai, Kenji Matsuno, Naohisa Ogo, Osamu Takahashi, Yoshiaki Masuda, Ayumu Muroya, Yasuto Akiyama, Tadashi Ashizawa, Tadashi Okawara
  • STAT3 inhibitor containing quinolinecarboxamide derivative as active ingredient
    Patent number: 8466290
    Abstract: The present invention provides a STATS inhibitor containing as an active ingredient, a quinolinecarboxamide derivative represented by the formula (I) (in the formula, W represents a bond or an alkylene chain; X represents O, S, or NR34; and R1 to R8 and R34 each represent H, halogen, alkyl, phenyl, furyl, thienyl, or the like), or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: June 18, 2013
    Assignees: Pharma IP General Incorporated Association, Pharma Design, Inc., Shizuoka Prefecture, Kumamoto Health Science University, Kabushiki Kaisha Yakult Honsha
    Inventors: Akira Asai, Kenji Matsuno, Naohisa Ogo, Takane Yokotagawa, Osamu Takahashi, Yasuto Akiyama, Tadashi Ashizawa, Tadashi Okawara
  • 1,3,4-OXADIAZOLE-2-CARBOXAMIDE COMPOUND
    Publication number: 20120302524
    Abstract: Provided is a 1,3,4-oxadiazole-2-carboxamide compound which has STAT3 inhibitory activity and is useful as an anticancer agent. Provided is a 1,3,4-oxadiazole-2-carboxamide compound represented by formula (I) or a pharmacologically acceptable salt thereof (in the formula, Ar represents a furyl group or the like; R1 represents a hydrogen atom or the like; and —X—Y represents a diaryl group such as a biphenyl group).
    Type: Application
    Filed: December 28, 2010
    Publication date: November 29, 2012
    Applicants: GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION, PHARMA DESIGN, INC., KABUSHIKI KAISHA YAKULT HONSHA, KUMAMOTO HEALTH SCIENCE UNIVERSITY, SHIZUOKA PREFECTURE
    Inventors: Akira Asai, Kenji Matsuno, Naohisa Ogo, Osamu Takahashi, Yoshiaki Masuda, Ayumu Muroya, Yasuto Akiyama, Tadashi Ashizawa, Tadashi Okawara
  • STAT3 INHIBITOR CONTAINING QUINOLINECARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT
    Publication number: 20110172429
    Abstract: The present invention provides a STATS inhibitor containing as an active ingredient, a quinolinecarboxamide derivative represented by the formula (I) (in the formula, W represents a bond or an alkylene chain; X represents O, S, or NR34; and R1 to R8 and R34 each represent H, halogen, alkyl, phenyl, furyl, thienyl, or the like.), or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: July 10, 2009
    Publication date: July 14, 2011
    Applicants: PHARMA IP GENERAL INCORPORATED ASSOCIATION, PHARMA DESIGN, INC., SHIZUOKA PREFECTURE, KUMAMOTO HEALTH SCIENCE UNIVERSITY, KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Akira Asai, Kenji Matsuno, Naohisa Ogo, Takane Yokotagawa, Osamu Takahashi, Yasuto Akiyama, Tadashi Ashizawa, Tadashi Okawara