Patents by Inventor Naoki Tsuno

Naoki Tsuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9290488
    Abstract: The disclosure relates to Azetidine-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein the R1, R2, R3, Q, Y1, Z, A, B, a, and b are as defined herein, compositions comprising an effective amount of an Azetidine-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an Azetidine-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: March 22, 2016
    Assignee: Purdue Pharma L.P.
    Inventors: Laykea Tafesse, Naoki Tsuno, Xiaoming Zhou
  • Patent number: 9278967
    Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: March 8, 2016
    Assignees: Purdue Pharma L.P., Shionogi & Co., Ltd.
    Inventors: Kouki Fuchino, R. Richard Goehring, Akira Matsumura, Bin Shao, Yoshiyuki Taoda, Naoki Tsuno, John William Frank Whitehead, Jiangchao Yao
  • Patent number: 9244205
    Abstract: A hard-coated antiglare film that has superior antiglare properties, allow high definition to be provided even in the case of a low haze value, can prevent white blur in an oblique direction from occurring and, and can improve the depth of black in black display, as well as a polarizing plate, and the like. The hard-coated antiglare film includes a transparent plastic film substrate and a hard-coating antiglare layer containing fine particles, which is on at least one surface of the transparent plastic film substrate. The hard-coated antiglare film has a total haze value Ht in the range of 10% to 35%. The total haze value Ht and an internal haze value Hin satisfy a relationship of 0.5?Hin/Ht?0.9. The surface of the hard-coating antiglare layer has an uneven shape and an arithmetic average surface roughness Ra in the range of 0.1 to 0.3 ?m.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: January 26, 2016
    Assignee: NITTO DENKO CORPORATION
    Inventors: Naoki Tsuno, Daisuke Hamamoto, Hiroki Kuramoto
  • Publication number: 20160009717
    Abstract: Compounds of Formula (I): where R1, R2, R5, a, and b are disclosed herein, and pharmaceutically acceptable derivatives thereof (a “Substituted-Quinoxaline-Type Bridged-Piperidine Compound”), compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Application
    Filed: September 18, 2015
    Publication date: January 14, 2016
    Inventors: Kouki FUCHINO, Naoki TSUNO, John W.F. WHITEHEAD, Jiangchao YAO
  • Patent number: 9206186
    Abstract: Provided herein are 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity. These compounds are useful for the treatment of diseases associated with CCR3 activity, including but not limited to, atopic dermatitis, allergic rhinitis, rheumatoid arthritis, Grave's disease, HIV infection, Alzheimer's disease, atherosclerosis and other inflammatory and/or immunological disorders.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: December 8, 2015
    Assignee: AXIKIN PHARMACEUTICALS, INC.
    Inventors: Yingfu Li, Kevin Bacon, Hiromi Sugimoto, Keiko Fukushima, Kentaro Hashimoto, Makiko Marumo, Toshiya Moriwaki, Noriko Nunami, Naoki Tsuno, Klaus Urbahns, Nagahiro Yoshida
  • Patent number: 9145408
    Abstract: Compounds of Formula (I): where R1, R2, R5, a, and b are disclosed herein, and pharmaceutically acceptable derivatives thereof (a “Substituted-Quinoxaline-Type Bridged-Piperidine Compound”), compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: September 29, 2015
    Assignees: Purdue Pharma L.P., Shionogi & Co., Ltd.
    Inventors: Naoki Tsuno, John W. F. Whitehead, Jiangchao Yao
  • Publication number: 20150238485
    Abstract: The present disclosure relates to Oxime-Substituted Quinoxaline-Type Piperidine Compounds, such as those of Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R20, R21, Q, Y1, Z, A, B, and a are as defined herein; compositions comprising an effective amount of an Oxime-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an Oxime-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Application
    Filed: May 7, 2015
    Publication date: August 27, 2015
    Inventors: Jeffrey Michael MARRA, Naoki TSUNO, Tatsuhiko UENO, Xiaoming ZHOU
  • Patent number: 9085561
    Abstract: The disclosure relates to Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein R1, R2, Qa, Y1, Z, A, B, Qx, E, G, J, M, U, W, and a are as defined herein, compositions comprising an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: July 21, 2015
    Assignees: Purdue Pharma L.P., Shionogi & Co., Ltd.
    Inventors: Naoki Tsuno, Tatsuhiko Ueno, Xiaoming Zhou
  • Patent number: 9040533
    Abstract: The present disclosure relates to Oxime-Substituted Quinoxaline-Type Piperidine Compounds, such as those of Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R20, R21, Q, Y1, Z, A, B, and a are as defined herein; compositions comprising an effective amount of an Oxime-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an Oxime-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: May 26, 2015
    Assignees: Purdue Pharma L.P., Shionogi & Co., Ltd.
    Inventors: Jeffrey Michael Marra, Naoki Tsuno, Tatsuhiko Ueno, Xiaoming Zhou
  • Publication number: 20150141643
    Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.
    Type: Application
    Filed: July 14, 2014
    Publication date: May 21, 2015
    Inventors: Kouki FUCHINO, R. Richard GOEHRING, Akira MATSUMURA, Bin SHAO, Yoshiyuki TAODA, Naoki TSUNO, John William Frank WHITEHEAD, Jiangchao YAO
  • Patent number: 8937181
    Abstract: The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3, Z, p and q are defined as set forth in the specification. The invention is also directed to the use compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: January 20, 2015
    Assignee: Purdue Pharma L.P.
    Inventors: Akira Matsumura, Hidenori Mikamiyama, Bin Shao, Naoki Tsuno, Jiangchao Yao
  • Publication number: 20150011529
    Abstract: The disclosure relates to Azetidine-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein the R1, R2, R3, Q, Y1, Z, A, B, a, and b are as defined herein, compositions comprising an effective amount of an Azetidine-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an Azetidine-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Application
    Filed: November 30, 2012
    Publication date: January 8, 2015
    Inventors: Laykea Tafesse, Naoki Tsuno, Xiaoming Zhou
  • Publication number: 20140345917
    Abstract: Provided are a double-sided transparent conductive film which is good in appearance even when its transparent conductive layers are patterned, and has anti-blocking property, thereby being producible at low costs; a wound body thereof; and a touch panel.
    Type: Application
    Filed: May 20, 2014
    Publication date: November 27, 2014
    Applicant: NITTO DENKO CORPORATION
    Inventors: Katsunori Takada, Naoki Hashimoto, Shinya Hiraoka, Kazuhiro Ikai, Hiroki Kuramoto, Hiroyuki Takao, Naoki Tsuno, Toru Umemoto
  • Patent number: 8853556
    Abstract: A transparent conductive film which comprises: a substrate composed of a non-crystalline polymer film; a first hard coating layer; a first transparent conductor layer; a first metal layer; a second hard coating layer; a second transparent conductor layer; and a second metal layer. The first hard coating layer includes a binder resin and a plurality of sphere-shaped particles having a diameter of 1 ?m to 5 ?m. The first metal layer has a plurality of projections having a maximum height Rz of 0.5 ?m to 2.5 ?m resulting from the plurality of particles included in the first hard coating layer on a surface thereof.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: October 7, 2014
    Assignee: Nitto Denko Corporation
    Inventors: Naoki Tsuno, Hiroyuki Takao, Katsunori Takada, Kazuhiro Ikai
  • Patent number: 8846929
    Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: September 30, 2014
    Assignees: Purdue Pharma L.P., Shionogi & Co., Ltd.
    Inventors: Kouki Fuchino, R. Richard Goehring, Bin Shao, Yoshiyuki Taoda, Naoki Tsuno, John William Frank Whitehead, Jiangchao Yao
  • Publication number: 20140187544
    Abstract: The present disclosure relates to Oxime-Substituted Quinoxaline-Type Piperidine Compounds, such as those of Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R20, R21, Q, Y1, Z, A, B, and a are as defined herein; compositions comprising an effective amount of an Oxime-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an Oxime-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Application
    Filed: December 23, 2013
    Publication date: July 3, 2014
    Applicants: Shionogi & Co., Ltd., Purdue Pharma L.P.
    Inventors: Jeffrey Michael MARRA, Naoki Tsuno, Tatsuhiko Ueno, Xiaoming Zhou
  • Patent number: 8742772
    Abstract: A touch panel sensor with which unevenness of interference can be reduced is provided. A touch panel sensor of the present invention includes a film base material, a first transparent electrode pattern formed on a first face of the film base material, a first adhesive layer laminated on the first face of the film base material so as to cover the first transparent electrode pattern, a second transparent electrode pattern formed on a second face of the film base material, and a second adhesive layer laminated on the second face of the film base material so as to cover the second transparent electrode pattern, and the film base material has an in-plane phase difference of ?/4 with respect to a wavelength ? in the visible light region.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: June 3, 2014
    Assignee: Nitto Denko Corporation
    Inventors: Hiroyuki Takao, Naoki Tsuno, Katsunori Takada
  • Publication number: 20140106131
    Abstract: A transparent conductive film for a display element which includes a black matrix having a polygonal opening and has a definition of 150 ppi or more, the transparent conductive film including: a transparent polymer base material; a transparent conductive layer; and a cured resin layer, wherein an outermost surface layer on a side where the cured resin layer is formed has a flat portion and a protrusion portion on the surface, a height of the protrusion portion is larger than 10 nm above the flat portion, and a maximum diameter of a cross-sectional shape formed by intersection of a surface parallel to the flat portion and the protrusion portion at a distance of 10 nm from the flat portion is smaller than a minimum value of distances between two non-adjacent sides of the opening of the black matrix.
    Type: Application
    Filed: October 8, 2013
    Publication date: April 17, 2014
    Applicant: NITTO DENKO CORPORATION
    Inventors: Kazuhiro Ikai, Katsunori Takada, Hiroki Kuramoto, Hiroyuki Takao, Naoki Tsuno
  • Publication number: 20140045830
    Abstract: The disclosure relates to Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein R1, R2, Qa, Y1, Z, A, B, Qx, E, G, J, M, U, W, and a are as defined herein, compositions comprising an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound.
    Type: Application
    Filed: July 26, 2013
    Publication date: February 13, 2014
    Applicants: Shionogi & Co., Ltd., Purdue Pharma L.P.
    Inventors: Naoki TSUNO, Tatsuhiko Ueno, Xiaoming Zhou
  • Publication number: 20140030484
    Abstract: A transparent conductive film which comprises: a substrate composed of a non-crystalline polymer film; a first hard coating layer; a first transparent conductor layer; a first metal layer; a second hard coating layer; a second transparent conductor layer; and a second metal layer. The first hard coating layer includes a binder resin and a plurality of sphere-shaped particles having a diameter of 1 ?m to 5 ?m. The first metal layer has a plurality of projections having a maximum height Rz of 0.5 ?m to 2.5 ?m resulting from the plurality of particles included in the first hard coating layer on a surface thereof.
    Type: Application
    Filed: October 4, 2013
    Publication date: January 30, 2014
    Applicant: NITTO DENKO CORPORATION
    Inventors: Naoki Tsuno, Hiroyuki Takao, Katsunori Takada, Kazuhiro Ikai