Abstract: An ophthalmic device includes a two-dimensional image acquisition unit that acquires a two-dimensional image by photographing the front of an eye to be examined with a color camera; a three-dimensional image acquisition unit that acquires a three-dimensional image of the eye to be examined by optical coherence tomography; and a correspondence definition data generation unit that generates correspondence definition data in which the position of a predetermined site of the eye to be examined in the three-dimensional image when the predetermined site is photographed as the three-dimensional image is associated with the position of the predetermined site in the two-dimensional image when the predetermined site is photographed as the two-dimensional image.

Abstract: An ophthalmic device includes a two-dimensional image acquisition unit that acquires a two-dimensional image by photographing the front of an eye to be examined with a color camera; a three-dimensional image acquisition unit that acquires a three-dimensional image of the eye to be examined by optical coherence tomography; and a correspondence definition data generation unit that generates correspondence definition data in which the position of a predetermined site of the eye to be examined in the three-dimensional image when the predetermined site is photographed as the three-dimensional image is associated with the position of the predetermined site in the two-dimensional image when the predetermined site is photographed as the two-dimensional image.

Abstract: An ophthalmic device includes a two-dimensional image acquisition unit that acquires a two-dimensional image by photographing the front of an eye to be examined with a color camera; a three-dimensional image acquisition unit that acquires a three-dimensional image of the eye to be examined by optical coherence tomography; and a correspondence definition data generation unit that generates correspondence definition data in which the position of a predetermined site of the eye to be examined in the three-dimensional image when the predetermined site is photographed as the three-dimensional image is associated with the position of the predetermined site in the two-dimensional image when the predetermined site is photographed as the two-dimensional image.

Abstract: A speed measuring device with an optical coherence tomography is provided. The speed measuring device includes an optical coherence tomography that obtains an tomographic image of a sample, a motion contrast calculator, a waveform creator that creates a motion contrast wave indicating chronological change of motion contrast, a time lag calculator, a distance calculator that calculates the blood vessel distance in a sample, and a speed calculator that calculates speed of a pulse wave transmitted inside the blood vessel.

Abstract: Optical coherence tomography (OCT) apparatuses and methods include a first electro-magnetic radiation (EMR) source providing EMR to a first optical path associated with a sample and a second optical path associated with a reference. A multi-beam generator unit (MBGU) generates first and second EMR beams having different wavelength contents. A scanning system illuminates the sample with the first and second EMR beams, at a first and second time, at a first and second location. An interference module generates interference signals based on received EMR returning from the reference and the first and second EMR beams returning from the sample. A detector generates detection signals based on received interference signals and a processor generates OCT data based on the processed detection signals. In some embodiments, three EMR beams having different wavelength contents with linearly independent vectors illuminate at least one same location of the sample.

Abstract: An ophthalmic device capable of obtaining B-scan graphical images at high speed while eliminating positional displacement due to movement of a subject eye. The device includes: anterior eye image obtaining means configured to obtain an image of an anterior eye of a subject eye; eye fundus image obtaining means configured to obtain an image of an eye fundus of the subject eye; and control means configured to detect a moving distance of the subject eye in the anterior eye image using means configured to calculate correlation between a moving distance of the subject eye in the anterior eye image and a moving distance in the eye fundus image, and to control a position for imaging of the eye fundus image based on the detected moving distance of the subject eye and the calculated correlation.

Abstract: A speed measuring device with an optical coherence tomography is provided. The speed measuring device includes an optical coherence tomography that obtains an tomographic image of a sample, a motion contrast calculator, a waveform creator that creates a motion contrast wave indicating chronological change of motion contrast, a time lag calculator, a distance calculator that calculates the blood vessel distance in a sample, and a speed calculator that calculates speed of a pulse wave transmitted inside the blood vessel.

Abstract: An ophthalmic device capable of obtaining B-scan graphical images at high speed while eliminating positional displacement due to movement of a subject eye. The device includes: anterior eye image obtaining means configured to obtain an image of an anterior eye of a subject eye; eye fundus image obtaining means configured to obtain an image of an eye fundus of the subject eye; and control means configured to detect a moving distance of the subject eye in the anterior eye image using means configured to calculate correlation between a moving distance of the subject eye in the anterior eye image and a moving distance in the eye fundus image, and to control a position for imaging of the eye fundus image based on the detected moving distance of the subject eye and the calculated correlation.

Abstract: Optical coherence tomography (OCT) apparatuses and methods include a first electro-magnetic radiation (EMR) source providing EMR to a first optical path associated with a sample and a second optical path associated with a reference. A multi-beam generator unit (MBGU) generates first and second EMR beams having different wavelength contents. A scanning system illuminates the sample with the first and second EMR beams, at a first and second time, at a first and second location. An interference module generates interference signals based on received EMR returning from the reference and the first and second EMR beams returning from the sample. A detector generates detection signals based on received interference signals and a processor generates OCT data based on the processed detection signals. In some embodiments, three EMR beams having different wavelength contents with linearly independent vectors illuminate at least one same location of the sample.

Abstract: Apparatus and method for optical coherence tomography. The method includes orienting a first optical path in a first selected orientation in space relative to a second optical path, having lights of the first optical path and the second optical path with no preferential polarization direction relationship. A sample is scanned with light from the first optical path and the second optical path. Light returning from the sample is directed, along the first optical path and the second optical path, to an optical pathway leading to a processing system. The processing system is configured to perform optical coherence tomography motion analysis based on interferences between at least one reference light and at least two lights returning from the sample, at two different instants, and from nearby scanned locations.

Abstract: An optical coherence tomography apparatus includes a multi-beam configuration unit comprising at least a first optical path having a first numerical aperture and a second optical path having a second numerical aperture. The multi-beam configuration unit orients the second optical path in a selected orientation in space relative to the first optical path. A scan system illuminates a sample with non-polarized light received from the multi-beam configuration unit and directs light returning from the sample to the first optical path and the second optical path. The multi-beam configuration unit directs light returning from the sample, along the first optical path and the second optical path, to an optical pathway leading to a processing system. The processing system performs optical coherence tomography motion analysis based on interference between light returning from the sample and a first reference signal.

Abstract: An optical coherence tomography apparatus includes a multi-beam configuration unit comprising at least a first optical path having a first numerical aperture and a second optical path having a second numerical aperture. The multi-beam configuration unit orients the second optical path in a selected orientation in space relative to the first optical path. A scan system illuminates a sample with non-polarized light received from the multi-beam configuration unit and directs light returning from the sample to the first optical path and the second optical path. The multi-beam configuration unit directs light returning from the sample, along the first optical path and the second optical path, to an optical pathway leading to a processing system. The processing system performs optical coherence tomography motion analysis based on interference between light returning from the sample and a first reference signal.

Abstract: When acute hepatitis progresses to fulminant hepatitis, a large amount of hepatic cells are rapidly broken, and as a result, the prognosis is seriously worsened. Thus, it is important to prognose the progress of acute hepatitis into fulminant hepatitis at an early stage and quickly start an appropriate treatment therefor. Although the prognosis of progress into fulminant hepatitis becomes possible owing to recent advances in test methods and diagnostic techniques, there has been no appropriate prophylactic/therapeutic agent for fulminant hepatitis. The present invention provides a therapeutic agent for acute hepatitis or a prophylactic/therapeutic agent for fulminant hepatitis with little side effect. The problem of the invention was solved by using a composition containing apolipoprotein A-II.

Abstract: The present invention provides an ophthalmologic apparatus that can noninvasively measure the state of the lacrimal layer formed on the cornea surface and that can quantitatively measure the state of the lacrimal layer without utilizing a reflection image from the retina. The ophthalmologic apparatus according to the present invention comprises an optical projection system for projecting light of a specified pattern onto a cornea surface, and an imaging device for photographing a reflection image of the projected light from the cornea surface. An operating unit calculates the degree of distortion of the reflection image on the basis of the density value distribution of the image photographed by the imaging device. The operating unit can determine the state of the lacrimal layer using the calculated degree of distortion.

Abstract: The present invention provides an opthalmologic apparatus that can noninvasively measure the state of the lacrimal layer formed on the cornea surface and that can quantitatively measure the state of the lacrimal layer without utilizing a reflection image from the retina. The opthalmologic apparatus according to the present invention comprises an optical projection system for projecting light of a specified pattern onto a cornea surface, and an imaging device for photographing a reflection image of the projected light from the cornea surface. An operating unit calculates the degree of distortion of the reflection image on the basis of the density value distribution of the image photographed by the imaging device. The operating unit can determine the state of the lacrimal layer using the calculated degree of distortion.