Abstract: RNA molecules for RNA interference to target a mutant allele with a point mutation, wherein the molecule has a nucleotide sequence complementary to a nucleotide sequence of a coding region of the mutant allele; and when counted from the base at the 5?-end in the nucleotide sequence complementary to the sequence of the mutant allele: a base at position 5 or 6 is mismatched with a base in the mutant allele; a base at position 10 or 11 is at the position of the point mutation and is identical to the base at the position of the point mutation in the mutant allele; the group at the 2?-position of the pentose in the ribonucleotide at position 8 is modified with OCH3, halogen, or LNA; and the group at the 2?-position of the pentose in the ribonucleotide at position 7 is not modified with any of OCH3, halogen, and LNA.

Abstract: A vehicle system includes a plurality of devices and a controller. The plurality of devices are mounted on the vehicle, and each of the devices implements a function having a safety standard of a predetermined level set therein. The controller is capable of executing processing related to the safety standard on the devices, and includes a plurality of ECUs respectively allocated for the levels of the safety standards. The plurality of ECUs are respectively connected to the devices in which the safety standards of the allocated levels are set without being connected to the devices in which the safety standards of different levels are set, and execute, on the connected devices, processing related to the safety standards according to the allocated levels. Accordingly, the vehicle system can appropriately construct a system that secures safety.

Abstract: A thermal acid generator having a high acid generation temperature, and a resist composition using the same.

Abstract: Methods and systems are provided for tracking anatomical features across multiple images. One example method includes outputting, for display on a display device, an annotation indicative of a first location of an identified anatomical feature of a first ultrasound image, the annotation generated based on a first output of a model and outputting, for display on the display device, an adjusted annotation based on a second output of the model, the second output of the model generated based on a second ultrasound image and further based on the first output of the model, the adjusted annotation indicative of a second location of the identified anatomical feature in the second ultrasound image.

Abstract: A thermal acid generator having a high acid generation temperature, and a resist composition using the same.

Abstract: Provided are: a thermal acid generator having a high acid generation temperature; and a resist composition using the same.

Abstract: Provided are: an oxime ester compound that is useful as a photopolymerization initiator used in a polymerizable composition; and a photopolymerization initiator containing the oxime ester compound. The oxime ester compound contains, in the same molecule: a group represented by the following Formula (I); and a photoradical cleavable group containing no oxime ester group: wherein, R1 and R2 each independently represent a hydrogen atom, a halogen atom, a nitro group, a cyano group or the like; one or more hydrogen atoms in the groups represented by R1 and R2 are optionally substituted with a halogen atom, a nitro group, a cyano group or the like; one or more methylene groups in the groups represented by R1 and R2 are optionally substituted with —O—, —CO—, —COO—, —OCO—, —NR3— or the like, provided that oxygen atoms are not arranged adjacent to one another; R3 represents a hydrogen atom or a hydrocarbon group having 1 to 20 carbon atoms; n represents 0 or 1; and * represents a bond.

Abstract: Methods and systems are provided for tracking anatomical features across multiple images. One example method includes outputting, for display on a display device, an annotation indicative of a first location of an identified anatomical feature of a first ultrasound image, the annotation generated based on a first output of a model and outputting, for display on the display device, an adjusted annotation based on a second output of the model, the second output of the model generated based on a second ultrasound image and further based on the first output of the model, the adjusted annotation indicative of a second location of the identified anatomical feature in the second ultrasound image.

Abstract: A system and method for analyzing ultrasound scenes to provide needle guidance and warnings is provided. The method includes acquiring, by an ultrasound system, an ultrasound image. The method includes segmenting, by at least one processor, the ultrasound image to identify a plurality of structures in the ultrasound image. The method includes highlighting, by the at least one processor, the plurality of structures in the ultrasound image to create a highlighted ultrasound image. The method includes presenting, by the at least one processor, the highlighted ultrasound image at a display system. The method includes determining, by the at least one processor, a distance between at least two of the plurality of structures in the ultrasound image. The method includes providing, by the at least one processor, a warning if the distance between the at least two of the plurality of structures in the ultrasound image is less than a threshold.

Abstract: A system and method for facilitating interaction by an ultrasound operator with an artificial intelligence segmentation module configured to identify and track biological and/or artificial structures in ultrasound images is provided. The method includes acquiring an ultrasound image and segmenting the ultrasound image with artificial intelligence to identify structure(s) in the ultrasound image. The method includes labeling the structure(s) in the ultrasound image to create a labeled ultrasound image. The method includes presenting the labeled ultrasound image at a display system. The method includes receiving a user selection of at least one target corresponding with at least one labeled structure. The method includes tracking the selected target(s) by identifying the selected target(s) in subsequently acquired ultrasound images.

Abstract: Provided are: a thermal acid generator having a high acid generation temperature; and a resist composition using the same.

Abstract: Provided are: a negative photosensitive composition which exhibits excellent sensitivity at the time of being cured and yields a cured article having excellent heat resistance; a cured article thereof; and a method of curing the same.

Abstract: Provided are: a positive photosensitive composition that exhibits excellent sensitivity at a time of being cured; a pattern using the same; and a method of producing a pattern.

Abstract: An oxime ester compound represented by general formula (I), wherein R1to R8 are as defined in the description, and n is 0 or 1; a photopolymerization initiator containing the compound; a photosensitive composition, alkali-developable photosensitive resin composition, and colored alkali-developable photosensitive resin composition containing the photopolymerization initiator; and a cured product of these compositions are provided. The compound is useful as a high-sensitivity photopolymerization initiator that has good stability and low sublimability and that efficiently absorbs, and is activated by, near-ultraviolet light, e.g., at 365 nm.

Abstract: The present invention provides oxime ester compounds represented by general formula (I), a photopolymerization initiator using said compound, and a photosensitive composition, alkali-developable photosensitive resin composition, and colored alkali-developable photosensitive resin composition containing same, and cured products thereof. The compounds of the present invention have excellent stability and low sublimability, and are useful as highly sensitive photopolymerization initiators that are activated by efficiently absorbing near ultraviolet light of 365 nm, etc. (I) (See the Specification for the definitions of R1-R8 in the formula. n represents 0 or 1.

Abstract: Feeder sections to be a target of interchange are to be expanded in order to improve the effect of power interchange between feeders. A control device for railway power conditioner is connected to a first feeder connected to a load side of a transformer in a first railway substation including a transformer receiving power from a power grid, and a second feeder connected to a load side of a transformer in a second railway substation including a transformer receiving power from a power grid, and decides an amount of power interchanged between the first and second feeders. The control device decides the amount of power interchanged between the first and second feeders, using the received power in the first railway substation and power on the first feeder, and the received power in the second railway substation and power on the second feeder.

Abstract: An alkali developable photosensitive resin composition contains (J) a photopolymerizable unsaturated compound having a structure resulting from the addition reaction of (B) a compound having a ?-diketone moiety or a compound having a ?-ketoester group to the (meth)acryloyl group of (A) a compound having at least two (meth)acryloyl groups and a hydroxyl group and subsequent esterification of the hydroxyl group of the resulting addition product with (C) a polybasic acid anhydride. The compound having a ?-diketone moiety is preferably a novel ?-diketone compound represented by general formula (I): wherein R1 is a C1-C20 alkyl group; R2 represents R11, OR11, COR11, SR11, CONR12R13, or CN; R11, R12, and R13 are each hydrogen, a C1-C20 alkyl group, etc.; a is 0 to 3; and b is 0 to 4.

Abstract: An input device includes a plurality of manipulation portions; an input function portion manipulated by the manipulation portions to perform an input function; a light guiding sheet facing the rear side of the plurality of manipulation portions; and a light source applying light into the light guiding sheet, wherein a rear surface opposite to a front surface of the light guiding sheet facing the manipulation portions is provided with a plurality of concave portions which is depressed to the inside of the light guiding sheet, wherein each concave portion has a circular opening and an inner surface which is a smooth concave curve surface, and wherein light propagated through the inside of the light guiding sheet is reflected by the inner surface toward the inside of the light guiding sheet, and the light is applied from the front surface of the light guiding sheet to the manipulation portions.

Abstract: A colored alkali-developable photosensitive resin composition comprising an alkali-developable resin composition that contains a reaction product obtained by esterification of an epoxy-adduct with a polybasic acid anhydride (C) and then with a polyfunctional epoxy compound (D), wherein the epoxy-adduct has a structure in which an unsaturated monobasic acid (B) is added to an epoxy resin (A) represented by general formula (I) below, a coloring material (E) and a photopolymerization initiator (F).

Abstract: An alkali-developable, colored photosensitive resin composition obtained by adding a colorant and a photopolymerization initiator to an alkali-developable resin composition, containing a reaction product obtained by esterification between an epoxy adduct and a polybasic acid anhydride, the epoxy adduct having a structure formed by adding an unsaturated monobasic acid and a compound selected from a phenol compound, an alcohol compound, an amine compound, and a carboxylic acid to an epoxy resin represented by general formula. The epoxy adduct is formed by adding 0.1 to 1.0 carboxyl group of the unsaturated monobasic acid and 0 to 0.9 phenolic hydroxyl group, alcoholic hydroxyl group, amino group or carboxyl group per epoxy group of the epoxy resin, with the sum of the carboxyl unsaturated monobasic acid and the phenolic hydroxyl group, alcoholic hydroxyl, amino or carboxyl group being 0.1 to 1.0 per epoxy group.