Abstract: Provided herein are compounds of formula (1): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein X1, X2, Ry, Rz, R1, R2, R3, and R4 are as defined herein. Also provided herein is a pharmaceutically acceptable composition comprising a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided herein are methods of using a compound of formula (I), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, to treat various diseases, disorders, and conditions responsive to the modulation of the contractility of the skeletal sarcomere.

Abstract: The automatic analysis device 100 is provided with: a specimen dispensing mechanism 101 that dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers 103; reaction containers 104 that contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanism 106 that dispenses a reagent into the reaction containers 104; and a detecting unit 113 which applies light from a light source 115 to the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers 104, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light.

Abstract: A vehicular electronic device has a semiconductor package and a multilayer wiring board. An electrode pad of the multilayer wiring board, to which a signal terminal of the semiconductor package is soldered, has a wiring pattern in an inner layer of the multilayer wiring board. A solder resist is applied and spaced from a periphery of the electrode pad to the exterior. The signal terminal is soldered to the electrode pad to cover an upper surface and an upper end of a side surface of the electrode pad. As a result, a crack is less likely to occur in solder connected to the signal terminal. Therefore, the signal terminal can be electrically connected with high reliability even when the signal terminal is provided in the semiconductor package with a small number.

Abstract: A vehicular electronic device has a semiconductor package and a multilayer wiring board. An electrode pad of the multilayer wiring board, to which a signal terminal of the semiconductor package is soldered, has a wiring pattern in an inner layer of the multilayer wiring board. A solder resist is applied and spaced from a periphery of the electrode pad to the exterior. The signal terminal is soldered to the electrode pad to cover an upper surface and an upper end of a side surface of the electrode pad. As a result, a crack is less likely to occur in solder connected to the signal terminal. Therefore, the signal terminal can be electrically connected with high reliability even when the signal terminal is provided in the semiconductor package with a small number.

Abstract: An image processing apparatus generates a main image as an image satisfying a main composition condition indicating a condition regarding a predetermined composition. The image processing apparatus includes: a condition determining unit that determines whether a captured image obtained through imaging of an imaging unit satisfies a preliminary composition condition which is based on the main composition condition; a processing unit that executes a process of obtaining a preliminary image as an image satisfying the preliminary composition condition in accordance with the determination result of the condition determining unit; and an image processing unit that generates the main image by processing the preliminary image obtained through the process based on the main composition condition.

Abstract: An image processing apparatus generates a main image as an image satisfying a main composition condition indicating a condition regarding a predetermined composition. The image processing apparatus includes: a condition determining unit that determines whether a captured image obtained through imaging of an imaging unit satisfies a preliminary composition condition which is based on the main composition condition; a processing unit that executes a process of obtaining a preliminary image as an image satisfying the preliminary composition condition in accordance with the determination result of the condition determining unit; and an image processing unit that generates the main image by processing the preliminary image obtained through the process based on the main composition condition.

Abstract: The present invention is directed to a presentation supporting system with the improved picture quality at colored edges of a resulting image.