Abstract: A drug delivery composition for delivering a drug to the spinal cord, the drug delivery composition containing a block copolymer having a polyethylene glycol segment and a hydrophobic polyester segment linked together, and a membrane-permeable peptide, in which the drug delivery composition is administered nasally. A pharmaceutical composition for treating a spinal cord disease, the pharmaceutical composition containing the above-mentioned drug delivery composition and a drug for treatment of a spinal cord disease, in which the pharmaceutical composition is administered nasally.

Abstract: An error diagnosis device diagnosing if location measurement error has occurred in a location measurement sensor measuring a self-location of a vehicle has a storing part storing map information divided in every road sections; a location acquiring part acquiring self-location information of the vehicle measured by the location measurement sensor; a drive section identifying part identifying road sections on which the vehicle has been driven in the map information, based on the self-location information; and an error diagnosis part. The error diagnosis part judges that there is location measurement error in the location measurement sensor when a first and second road sections of one of the road sections identified as having been driven on by the vehicle are not consecutive, and judges that there is no location measurement error in the location measurement sensor when the first road section and the second road section are consecutive.

Abstract: A snap ring is set to a set portion of a shaft of a rotator from a direction orthogonal to an axial direction of the shaft. The snap ring includes a first arcuate portion and a second arcuate portion facing each other, being elastically deformable in directions away from each other, holding the set portion by elastic deformation restoring force. One ends of the first and second arcuate portions are away from each other to form an insertion portion to insert the set portion. When the snap ring is not used, the first arcuate portion has a same radius of curvature as the second arcuate portion and the set portion, and a center of curvature closer to the second arcuate portion than the first arcuate portion, and the second arcuate portion has a center of curvature closer to the first arcuate portion than the second arcuate portion.

Abstract: To provide electrolytic manganese dioxide excellent in cell performance in high rate discharge and middle rate discharge when used as a cathode material for alkaline manganese dry cells, and a method for its production. Electrolytic manganese dioxide, characterized in that the average size of mesopores is at least 6.5 nm and at most 10 nm, and the alkali potential is at least 290 mV and at most 350 mV; a method for its production and its application.

Abstract: The present invention provides a method and a reagent for increasing lentiviral vector production in 293T cells. When the 293T cells are cotransfected with a packaging mix comprising a plurality of plasmids that comprise genes encoding proteins essential for lentiviral particle formation and a plasmid that comprises a gene transcribed into RNA to be incorporated into lentiviral particles containing a transgene to be expressed in target cells according to the method for producing a lentiviral vector, HTLV-1 Tax, HIV-1 Tat, or NF-?B RelA are coexpressed in the 293T cells, so as to increase the amount of lentiviral vector production.

Abstract: To provide electrolytic manganese dioxide excellent in low rate characteristics and middle rate characteristics when used as a cathode material for alkaline manganese dry cells, and a method for its production. Electrolytic manganese dioxide of which the apparent density is at least 4.0 g/cm3 and at most 4.3 g/cm3, and the mode particle size is at least 30 ?m and at most 100 ?m; a method for its production and its application.

Abstract: A sheet conveying device, which is included in a fixing device and an image forming apparatus, includes a sheet contacting body and a lateral relative position shifting body. The sheet contacting body is configured to contact a sheet to be conveyed. The lateral relative position shifting body is configured to shift a passing position of the sheet being conveyed toward the sheet contacting body, in a width direction perpendicular to a sheet conveying direction and a relative position to the sheet contacting body, each time the sheet is conveyed by a number of sheets based on a setting. The setting of the number of sheets varies based on information of the sheet.

Abstract: An automatic analyzer is capable of transporting a sample at an optimum timing and a method of transporting the sample. An automatic analyzer includes an analysis unit which measures a sample, a transport unit which transports the sample to the analysis unit, and a control unit which controls the analysis unit and the transport unit. A sample is transported to the analysis unit by a time of starting an aspirating operation on the sample by allowing the analysis unit to perform a pre-measurement operation for each measuring method which needs to be performed before aspirating the sample even when the sample is still in the transport unit.

Abstract: A snap ring is set to a set portion of a shaft of a rotator from a direction orthogonal to an axial direction of the shaft. The snap ring includes a first arcuate portion and a second arcuate portion facing each other, being elastically deformable in directions away from each other, holding the set portion by elastic deformation restoring force. One ends of the first and second arcuate portions are away from each other to form an insertion portion to insert the set portion. When the snap ring is not used, the first arcuate portion has a same radius of curvature as the second arcuate portion and the set portion, and a center of curvature closer to the second arcuate portion than the first arcuate portion, and the second arcuate portion has a center of curvature closer to the first arcuate portion than the second arcuate portion.

Abstract: An automatic analyzer is capable of ensuring sufficient nozzle cleaning and suppressing of deterioration in the accuracy of analysis. When it is judged that there remains no analysis item of the sample, a judgment is made on whether the sample dispensation quantity of the n-th sample dispensation is less than a dispensation quantity threshold value or not, and if less, a cleaning pattern is selected by making a judgment on whether or not all the sample dispensation quantities of the first through (n?1)-th sample dispensations are less than the dispensation quantity threshold value. If the sample dispensation quantity of the n-th sample dispensation is the dispensation quantity threshold value or more, another cleaning pattern selected by making the judgment on whether or not all the sample dispensation quantities of the first through (n?1)-th sample dispensations are less than the dispensation quantity threshold value.

Abstract: The welding chip heats and melts the first welded part and the second welded part, and includes a projected part, a first extension part, and a second extension part. The projected part has a tubular shape with a bottom. One end of the tubular shape extending in a predetermined direction opens and the other end of the tubular shape is closed. The projected part is pushed into the first welded part and the second welded part in the predetermined direction from the opening one end of the tubular shape. The first extension part has a shape extending from a tube outer surface of the projected part and extending annularly around the predetermined direction. The second extension part has a shape extending from the first extension part to the opening one end of the projected part in the predetermined direction and extending annularly around the predetermined direction.

Abstract: The automatic analysis device 100 is provided with: a specimen dispensing mechanism 101 that dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers 103; reaction containers 104 that contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanism 106 that dispenses a reagent into the reaction containers 104; and a detecting unit 113 which applies light from a light source 115 to the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers 104, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light.

Abstract: Please substitute the new Abstract submitted herewith for the original Abstract: The present invention reduces the turnaround time of an automated analyzer. During a period when cyclic measurement by a measurement unit is unnecessary, a controller washes a reaction vessel using a washing cycle having a cycle time shorter than that of an analysis cycle. A single analysis cycle and a single washing cycle both include a reaction disc stopping period and rotation period. In the washing cycle, there is no time during the stopping period when a sample dispensing mechanism, reagent dispensing mechanism, or stirring mechanism operates but there is a time when a washing mechanism operates. The washing cycle stopping period is shorter than the analysis cycle stopping period. The amount of rotation of the reaction disk in the analysis cycle rotation period is the same as the amount of rotation of the reaction disk in the washing cycle rotation period.

Abstract: This automated analysis device is provided with a plurality of analysis units for analyzing a specimen, a buffer portion which holds a plurality of specimen racks on which are placed specimen containers holding the specimen, a sampler portion which conveys the specimen racks held in the buffer portion to the analysis units, and a control portion which, when performing a process to deliver the specimen racks to the plurality of analysis units, outputs synchronization signals to all the plurality of analysis units, wherein the analysis unit performs a delivery process starting from the synchronization signal, and the analysis unit performs a delivery process starting from the synchronization signal.

Abstract: The automatic analysis device 100 is provided with: a specimen dispensing mechanism 101 that dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers 103; reaction containers 104 that contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanism 106 that dispenses a reagent into the reaction containers 104; and a detecting unit 113 which applies light from a light source 115 to the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers 104, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light.

Abstract: A welding method heats and pressurizes a contacting portion, where a first member and a second member made of resin are in contact with each other, by a pressing tool. The welding method has forming a step, forming a recessed portion, crushing a protrusion, and filling the recessed portion. The step is defined between the first member and the second member by providing the protrusion to the first member. The recessed portion is provided in a tip of the pressing tool. The protrusion of the first member is crushed in the recessed portion by being pressed toward the second member using the pressing tool. The recessed portion is filled with the molten portion of the first member and the molten portion of the second member such that a rim of an outer periphery of the recessed portion is dug into the first member and the second member.

Abstract: The purpose of the present invention is to provide an automatic analysis device capable of efficiently performing a plurality of analyses, while reducing the footprint and cost of the device. Provided is an automatic analysis device characterized by being provided with containers for containing samples, one rack for placing the containers thereon, and a control unit, the control unit generating, with respect to the one rack, a plurality of registration patterns in which information of the positions where the containers are disposed, and information of the samples contained in the containers are correlated with each other, storing the registration patterns thus generated, applying, to the one rack, one registration pattern selected from among the registration patterns thus stored, and analyzing the samples. Also provided is an analysis method using the device.

Abstract: A fixing device includes a fixing rotator, a pressure rotator, and a pressure assembly that forms a fixing nip therebetween and includes a first adjuster and a second adjuster. The first adjuster includes a pressure cam, a first biasing device, a first pressure lever that holds the pressure rotator, and a second pressure lever that moves with the pressure cam and presses against the first pressure lever via the first biasing device. The first adjuster adjusts a load of the first biasing device to adjust a pressure force from the pressure rotator to the fixing rotator. The second adjuster includes an adjustment screw is driven into the second pressure lever, and a retainer that retains an adjusted state between the adjustment screw and the first pressure lever. The second adjuster adjusts a holding position of the first pressure lever to hold the pressure rotator.

Abstract: The welding chip heats and melts the first welded part and the second welded part, and includes a projected part, a first extension part, and a second extension part. The projected part has a tubular shape with a bottom. One end of the tubular shape extending in a predetermined direction opens and the other end of the tubular shape is closed. The projected part is pushed into the first welded part and the second welded part in the predetermined direction from the opening one end of the tubular shape. The first extension part has a shape extending from a tube outer surface of the projected part and extending annularly around the predetermined direction. The second extension part has a shape extending from the first extension part to the opening one end of the projected part in the predetermined direction and extending annularly around the predetermined direction.

Abstract: A sheet conveying device, which is included in a fixing device and an image forming apparatus, includes a sheet contacting body and a lateral relative position shifting body. The sheet contacting body is configured to contact a sheet to be conveyed. The lateral relative position shifting body is configured to shift a passing position of the sheet being conveyed toward the sheet contacting body, in a width direction perpendicular to a sheet conveying direction and a relative position to the sheet contacting body, each time the sheet is conveyed by a number of sheets based on a setting. The setting of the number of sheets varies based on information of the sheet.