Patents by Inventor Narendra Bam

Narendra Bam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating cancer by administering conjugates comprising human IL-18 and substitution mutants thereof
    Patent number: 7736639
    Abstract: Methods of treating cancer in patients in need thereof with human interleukin-18 (IL-18) polypeptides and substitution mutants thereof that are conjugated to water-soluble polymers at specific sites on the human IL-18 protein are disclosed.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: June 15, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Narendra Bam, Jacob Bongers, Robert B. Kirkpatrick, Cheryl A. Janson, Zdenka Jonak, Xianyang Qiu, Ping Yeh, Kyung Johanson
  • METHOD OF TREATING CANCER BY ADMINISTERING CONJUGATES COMPRISING HUMAN IL-18 AND SUBSTITUTION MUTANTS THEREOF
    Publication number: 20080206189
    Abstract: Human interleukin-18 (IL-18) polypeptides and substitution mutants thereof were conjugated to water-soluble polymers at specific sites on the human IL-18 protein. These conjugated human IL-18 and substitution mutants thereof retain biological activity. These conjugated cytokines demonstrate enhanced and unexpected biological properties when compared to the corresponding unconjugated cytokines.
    Type: Application
    Filed: December 21, 2007
    Publication date: August 28, 2008
    Inventors: Narendra BAM, Jacob Bongers, Robert B. Kirkpatrick, Cheryl A. Janson, Zdenka Jonak, Xianyang Qiu, Ping Yeh, Kyung Johanson
  • Conjugates comprising human IL-18 and substitution mutants thereof
    Patent number: 7311902
    Abstract: Human interleukin-18 (IL-18) polypeptides and substitution mutants thereof were conjugated to water-soluble polymers at specific sites on the human IL-18 protein. These conjugated human IL-18 and substitution mutants thereof retain biological activity. These conjugated cytokines demonstrate enhanced and unexpected biological properties when compared to the corresponding unconjugated cytokines.
    Type: Grant
    Filed: April 14, 2004
    Date of Patent: December 25, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Narendra Bam, Jacob Bongers, Robert B. Kirkpatrick, Cheryl A. Janson, Zdenka Jonak, Xianyang Qiu, Ping Yeh, Kyung Johanson
  • Chemokine conjugates
    Publication number: 20070031368
    Abstract: Low molecular weight polypeptides with chemokine activity were conjugated to water-soluble polymers and retain biological activity. These conjugated chemokines demonstrate enhanced and unexpected biological properties when compared to unconjugated chemokines.
    Type: Application
    Filed: October 12, 2006
    Publication date: February 8, 2007
    Inventors: Narendra Bam, Andrew King, Ping-Yang Yeh, Charles Davis
  • Conjugates comprising human IL-18 and substitution mutants thereof
    Publication number: 20050008615
    Abstract: Human interleukin-18 (IL-18) polypeptides and substitution mutants thereof were conjugated to water-soluble polymers at specific sites on the human IL-18 protein. These conjugated human IL-18 and substitution mutants thereof retain biological activity. These conjugated cytokines demonstrate enhanced and unexpected biological properties when compared to the corresponding unconjugated cytokines.
    Type: Application
    Filed: April 14, 2004
    Publication date: January 13, 2005
    Inventors: Narendra Bam, Jacob Bongers, Robert Kirkpatrick, Cheryl Janson, Zdenka Jonak, Xianyang Qiu, Ping Yeh, Kyung Johanson
  • Chemokine conjugates
    Publication number: 20030175238
    Abstract: Low molecular weight polypelptides with chemokine activity were conjugated to water-soluble polymers and retain biological activity. These conjugated chemokines demonstrate enhanced and unexpected biological properties when compared to unconjugated chemokines.
    Type: Application
    Filed: December 20, 2002
    Publication date: September 18, 2003
    Inventors: Narendra Bam, Andrew G King, Ping-Yang Yeh, Charles Davis
  • Method for purifying alcohol esters
    Patent number: 5424467
    Abstract: Triglycerides, such as vegetable oils and animal fats, are esterified with alcohols to produce alcohol esters which can be used as alternative fuel sources. By-products of the transesterification reaction are stripped from the effluent of the transesterification reactor using a recovery alcohol that can be an isolated by-product of the transesterification reaction.
    Type: Grant
    Filed: July 14, 1993
    Date of Patent: June 13, 1995
    Assignee: Idaho Research Foundation
    Inventors: Narendra Bam, David C. Drown, Roger Korus, Dwight S. Hoffman, Timothy G. Johnson, Jacqueline M. Washam