Patents by Inventor Nariyasu Mano

Nariyasu Mano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diffusion promoting device for low flow velocity gradient high performance liquid chromatography
    Patent number: 7229551
    Abstract: Device for improving detection sensitivity in low flow velocity high performance liquid chromatographic apparatus. Preferredly, diffusion promoting device connected at just before separation column and having function of improving detection sensitivity for use in low flow velocity high performance liquid chromatographic apparatus. Also, method for improving detection sensitivity in low flow velocity high performance liquid chromatographic apparatus.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: June 12, 2007
    Assignee: Eisai Co., Ltd.
    Inventors: Kaoru Murata, Nariyasu Mano, Naoki Asakawa
  • Atisane compounds and use thereof
    Patent number: 7211589
    Abstract: The present invention provides a novel compound exhibiting an excellent suppressing effect to cell injury caused by radicals and neurotoxicity induced by excitatory nuerotransmitters such as glutamate. Specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. Wherein Z represents a bivalent organic group and the like of from 2 to 3 carbon atom(s) which may have a substituent; and R3 represents a carboxyl group and the like.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: May 1, 2007
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Akinori Akaike, Hachiro Sugimoto, Yukio Nishizawa, Masahiro Yonaga, Naoki Asakawa, Naoki Asai, Nariyasu Mano, Taro Terauchi, Takashi Doko
  • Diffusion promoting device for low flow velocity gradient high performance liquid chromatography
    Publication number: 20050000875
    Abstract: Device for improving detection sensitivity in low flow velocity high performance liquid chromatographic apparatus. Preferredly, diffusion promoting device connected at just before separation column and having function of improving detection sensitivity for use in low flow velocity high performance liquid chromatographic apparatus. Also, method for improving detection sensitivity in low flow velocity high performance liquid chromatographic apparatus.
    Type: Application
    Filed: June 28, 2004
    Publication date: January 6, 2005
    Inventors: Kaoru Murata, Nariyasu Mano, Naoki Asakawa
  • Novel atisane compounds and use thereof
    Publication number: 20040180930
    Abstract: The present invention provides a novel compound exhibiting an excellent suppressing effect to cell injury caused by radicals and neurotoxicity induced by excitatory nuerotransmitters such as glutamate. Specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them.
    Type: Application
    Filed: October 9, 2003
    Publication date: September 16, 2004
    Inventors: Akinori Akaike, Hachiro Sugimoto, Yukio Nishizawa, Masahiro Yonaga, Naoki Asakawa, Naoki Asai, Nariyasu Mano, Taro Terauchi, Takashi Doko
  • Diffusion promoting apparatus for low flow velocity gradient high-speed liquid chromatography
    Patent number: 6780325
    Abstract: The present invention provides a device for improving detection sensitivity and a method for improving the detection sensitivity for use in a low flow velocity high performance liquid chromatographic apparatus. That is, the present invention is a diffusion promoting device connected at just before a separation column and having a function for improving detection sensitivity for use in a low flow velocity high performance liquid chromatographic apparatus.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: August 24, 2004
    Assignee: Eisai Co., Ltd.
    Inventors: Kaoru Murata, Nariyasu Mano, Naoki Asakawa
  • Splitted tubing apparatus for gradient high performance liquid chromatography
    Patent number: 6581442
    Abstract: The present invention provides a device capable of simply formulating an arbitrary gradient pattern in a low flow gradient high performance liquid chromatography. That is, the present invention provides a split tubing apparatus for a gradient high performance liquid chromatography, which comprises a solvent inlet part, a split tubing part split into two or more plural tubes, and a solvent outlet part.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: June 24, 2003
    Assignee: Eisai Co., Ltd.
    Inventors: Kaoru Murata, Yasushi Ishihama, Nariyasu Mano, Naoki Asakawa
  • Separating agent comprising bonded conalbumin
    Patent number: 5900144
    Abstract: Disclosed is an optical isomer separating agent composed of a stationary phase having a support and a chemically modified conalbumin. The separating agent may be used in a high-performance liquid chromatography column.
    Type: Grant
    Filed: June 2, 1993
    Date of Patent: May 4, 1999
    Assignee: Eisai Co., Ltd.
    Inventors: Nariyasu Mano, Yoshiya Oda, Toshinobu Miwa, Naoki Asakawa, Yutaka Yoshida, Tadashi Sato