Patents by Inventor Nathan Lockwood
Nathan Lockwood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20160175489Abstract: Embodiments of the disclosure include lubricious coatings. In an embodiment the disclosure includes a lubricious coating for a medical device including first and second coated layers. The first coated layer is between the second coated layer and the device surface and includes a vinyl pyrrolidone polymer and a photo reactive group. The second coated layer is in direct contact with the first coated layer and is a top coating that includes an acrylic acid polymer. The second coated layer can optionally include photoreactive groups. The coating was found to have a very low number of particulates (e.g., 10 ?m or greater) which is very desirable for in vivo use.Type: ApplicationFiled: February 29, 2016Publication date: June 23, 2016Inventors: David E. Babcock, Timothy M. Kloke, Joseph S. McGonigle, Nathan Lockwood, Bruce Jelle
-
Publication number: 20160089480Abstract: Embodiments of the invention include medical device elements formed from polymers with lubricious properties. In an embodiment, a method of forming a medical device element is included. The method can include mixing a first polymeric component and a second polymeric component to form a polymer mixture. The method can further include forming the polymer mixture into the medical device element. The method can also include treating the polymer mixture with at least one of an acid or a base. In an embodiment, a medical device is included. The medical device can include a lubricious element, the lubricious element comprising a mixture of a first polymeric component and a second polymeric component. The second polymeric component can include a polymer that is treated with at least one of an acid or a base after formation of the element. Other embodiments are also included herein.Type: ApplicationFiled: September 21, 2015Publication date: March 31, 2016Inventors: Ralph A. Chappa, Nathan A. Lockwood, Joseph Schmidt McGonigle
-
Publication number: 20160022502Abstract: Embodiments of the invention include wound packing devices and methods of making and using the same. In an embodiment, the invention includes a wound packing device including a plurality of spacing elements capable of absorbing exudate, wherein the surface of the spacing elements resist colonization by microorganisms. The wound packing device can also include a connector connecting the plurality of spacing elements to one another. Other embodiments are also included herein.Type: ApplicationFiled: August 6, 2015Publication date: January 28, 2016Inventors: Shawn Fuller, Bryan A. Claseman, Joram Slager, Jeffrey J. Missling, Gary Maharaj, Gary W. Opperman, Nathan A. Lockwood, Robert W. Hergenrother, Charles Olson
-
Patent number: 9177084Abstract: Methods, systems, and apparatus, including computer programs encoded on a system, for generating an analytical energy model from a conceptual representation or a mass form model.Type: GrantFiled: September 30, 2011Date of Patent: November 3, 2015Assignee: Autodesk, Inc.Inventors: Kyle Bernhardt, Lillian M. Smith, Jack Conrad Gray, Nathan Lockwood
-
Patent number: 9155671Abstract: Embodiments of the invention include wound packing devices and methods of making and using the same. In an embodiment, the invention includes a wound packing device including a plurality of spacing elements capable of absorbing exudate, wherein the surface of the spacing elements resist colonization by microorganisms. The wound packing device can also include a connector connecting the plurality of spacing elements to one another. Other embodiments are also included herein.Type: GrantFiled: October 16, 2013Date of Patent: October 13, 2015Assignee: SurModics, Inc.Inventors: Shawn Fuller, Bryan A. Claseman, Joram Slager, Jeffrey J. Missling, Gary Maharaj, Gary W. Opperman, Nathan Lockwood, Robert W. Hergenrother, Charles Olson
-
Publication number: 20150196497Abstract: A biocompatible polymeric controlled release matrix barrier structure for delivery of one or more bioactive agents from an implantable medical device is described. In an embodiment, a biocompatible polymeric controlled release matrix barrier structure is included. The biocompatible polymeric controlled release matrix can include a body structure formed of a compliant material comprising one or more compliant biocompatible polymers and one or more bioactive agents. The body structure can define a central aperture through which a subcutaneous element of an implantable medical device passes. Other embodiments are included herein.Type: ApplicationFiled: March 26, 2015Publication date: July 16, 2015Inventors: Joseph Schmidt McGonigle, Aleksey V. Kurdyumov, Jeffrey J. Missling, Nathan A. Lockwood, Kevin W. Burton, Beth A. Petersen
-
Patent number: 8956682Abstract: The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.Type: GrantFiled: April 2, 2013Date of Patent: February 17, 2015Assignee: Surmodics, Inc.Inventors: Nathan A. Lockwood, Bruce M. Jelle, Aleksey V. Kurdyumov
-
Patent number: 8802121Abstract: Silane-functionalized hydrophobic ?(1?4)glucopyranose polymers and polymeric matrices are described. Biodegradable matrices can be formed from hydrophobic ?(1?4)glucopyranose polymers with reactive pendent silyl ether groups. Reaction of the silyl ether groups provides improved matrix formation through bonding to a device surface of a device, polymer-polymer crosslinking, or both. Biodegradable matrices can be used for the preparation of implantable and injectable medical devices, including those that release a bioactive agent.Type: GrantFiled: June 2, 2010Date of Patent: August 12, 2014Assignee: Surmodics, Inc.Inventors: Aleksey V. Kurdyumov, Nathan A. Lockwood, Joram Slager, Dale G. Swan, Robert Hergenrother
-
Publication number: 20140200411Abstract: Disclosed herein are activatable conductive compositions and methods of making and using activatable conductive compositions. In particular, activatable conductive monomers polymers are described and electrically conductive coatings that include activatable conductive polymers.Type: ApplicationFiled: January 10, 2014Publication date: July 17, 2014Applicant: SurModics, Inc.Inventors: Bruce M. Jelle, Aleksey V. Kurdyumov, Joseph Schmidt McGonigle, Robert W. Hergenrother, Nathan A. Lockwood, Joseph Ventura, Sean M. Stucke
-
Publication number: 20140180229Abstract: Embodiments of the invention include wound packing devices and methods of making and using the same. In an embodiment, the invention includes a wound packing device including a plurality of spacing elements capable of absorbing exudate, wherein the surface of the spacing elements resist colonization by microorganisms. The wound packing device can also include a connector connecting the plurality of spacing elements to one another. Other embodiments are also included herein.Type: ApplicationFiled: October 16, 2013Publication date: June 26, 2014Inventors: Shawn Fuller, Bryan A. Claseman, Joram Slager, Jeffrey J. Missling, Gary Maharaj, Gary W. Opperman, Nathan Lockwood, Robert W. Hergenrother, Charles Olson
-
Publication number: 20140162083Abstract: The invention is directed to latent reactive and polymerizable derivatives of fluorescent stilbene-based compounds. The compounds can be used to provide articles with a fluorescence property, such as medical devices (e.g., catheters). The fluorescent compounds can be used in association with polymers, or can be incorporated into polymers, and the polymers used in a coating composition on the article surface. The compounds allow for visual or machine inspection of coating properties such as uniformity of coverage.Type: ApplicationFiled: December 12, 2013Publication date: June 12, 2014Applicant: SurModics, Inc.Inventors: Aleksey V. Kurdyumov, Dale G. Swan, Nathan A. Lockwood, Bruce M. Jelle
-
Patent number: 8697106Abstract: A wound spacer device comprising multiple beads connected by non-absorbable suture material is disclosed. The device can be applied, for example, by a first responder to an injured individual, or can be applied by a trauma treatment facility, such as a Level 2 medical unit. In typical embodiments the device allows for site-specific controlled elution of an antimicrobial agent, such as Tobramycin, including defined elution over a period of time, such as 48 or 72 hours.Type: GrantFiled: September 23, 2011Date of Patent: April 15, 2014Assignee: SurModics, Inc.Inventors: Tim M. Kloke, Steven J. Keough, Nathan Lockwood, Margaret R. Gardner, Robert W. Hergenrother, Ralph A. Chappa
-
Patent number: 8685421Abstract: A wound spacer device comprising multiple beads connected by non-absorbable suture material is disclosed. The device can be applied, for example, by a first responder to an injured individual, or can be applied by a trauma treatment facility, such as a Level 2 medical unit. In typical embodiments the device allows for site-specific controlled elution of an antimicrobial agent, such as Tobramycin, including defined elution over a period of time, such as 48 or 72 hours.Type: GrantFiled: July 6, 2007Date of Patent: April 1, 2014Assignee: SurModics, Inc.Inventors: Tim M. Kloke, Steven J. Keough, Nathan Lockwood, Margaret R. Gardner, Robert W. Hergenrother, Ralph A. Chappa
-
Publication number: 20130261566Abstract: The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.Type: ApplicationFiled: April 2, 2013Publication date: October 3, 2013Applicant: SurModics, Inc.Inventors: Nathan A. Lockwood, Bruce M. Jelle, Aleksey V. Kurdyumov
-
Publication number: 20130085718Abstract: Methods, systems, and apparatus, including computer programs encoded on a system, for generating an analytical energy model from a conceptual representation or a mass form model.Type: ApplicationFiled: September 30, 2011Publication date: April 4, 2013Inventors: Kyle Bernhardt, Lillian M. Smith, Jack Conrad Gray, Nathan Lockwood
-
Publication number: 20120021038Abstract: A wound spacer device comprising multiple beads connected by non-absorbable suture material is disclosed. The device can be applied, for example, by a first responder to an injured individual, or can be applied by a trauma treatment facility, such as a Level 2 medical unit. In typical embodiments the device allows for site-specific controlled elution of an antimicrobial agent, such as Tobramycin, including defined elution over a period of time, such as 48 or 72 hours.Type: ApplicationFiled: September 23, 2011Publication date: January 26, 2012Applicant: Surmodics, Inc.Inventors: Tim M. Kloke, Steven J. Keough, Nathan Lockwood, Margaret R. Gardner, Robert W. Hergenrother, Ralph A. Chappa
-
Patent number: 8097457Abstract: The present invention is directed to liquid crystalline substrates useful in the culture of cells and methods of their use. In certain embodiments, the invention provides methods and devices for imaging changes (e.g., reorganization) of extracellular matrix components by living cells.Type: GrantFiled: April 13, 2011Date of Patent: January 17, 2012Assignee: Wisconsin Alumni Research FoundationInventors: Nicholas L. Abbott, Jeffrey C. Mohr, Christopher J. Murphy, Elise Huang, Juan J. DePablo, Nathan A. Lockwood, Sean P. Palecek
-
Patent number: 8062853Abstract: The present invention is directed to methods for providing a polyelectrolyte multilayer film at a liquid-liquid interface. Such methods include steps of sequentially-depositing layers of cationic and anionic polyelectrolytes at a liquid-liquid interface that is formed between immiscible first and second liquids whereby a polyelectrolyte multilayer film is provided at the liquid-liquid interface. In certain preferred embodiments, the first liquid is an aqueous solution and the second liquid is a liquid crystal. In alternative embodiments, the first liquid is an aqueous solution and the second liquid is an oil. The invention further encompasses polyelectrolyte multilayer films provided by the disclosed methods as well as applications utilizing such materials.Type: GrantFiled: January 11, 2010Date of Patent: November 22, 2011Assignee: Wisconsin Alumni Research FoundationInventors: Nicholas Abbott, Nathan A. Lockwood, Katie D. Cadwell, Frank Caruso, Elvira Tjipto
-
Publication number: 20110195498Abstract: The present invention is directed to liquid crystalline substrates useful in the culture of cells and methods of their use. In certain embodiments, the invention provides methods and devices for imaging changes (e.g., reorganization) of extracellular matrix components by living cells.Type: ApplicationFiled: April 13, 2011Publication date: August 11, 2011Applicant: Wisconsin Alumni Research FoundationInventors: Nicholas L. Abbott, Jeffrey C. Mohr, Christopher J. Murphy, Elise Huang, Juan J. De Pablo, Sean P. Palecek, Nathan A. Lockwood
-
Publication number: 20110159072Abstract: A biocompatible polymeric controlled release matrix for delivery of one or more bioactive agents from an implantable medical device is described. In one embodiment, the polymeric controlled release matrix is a complaint film that includes one or more compliant biocompatible polymers and one or more bioactive agents. In another embodiment, the polymeric controlled release matrix is an elastomeric collar that includes one or more elastomeric biocompatible polymers and one or more bioactive agents.Type: ApplicationFiled: December 29, 2010Publication date: June 30, 2011Applicant: SurModics, Inc.Inventors: Jeffrey J. Missling, Nathan Lockwood, Kevin W. Burton, Beth A. Petersen