Abstract: A composition is provided for removal of a target substance from a fluid stream. The composition may be used to remove polyfluorinated alkyl substances (PFAS) from water. The composition comprises a support material comprising an alumina; and a sorbent molecule that comprises a core polymer; wherein the core polymer is covalently linked to the support material; and wherein the sorbent molecule further comprises one or more covalently linked sorbent groups. Processes for removal of target substances such as PFAS are also provided.

Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Biological effects may include upregulating and downregulating inflammatory immune response molecules within a target tissue. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths.

Abstract: A compression device is used to increase intra-luminal pressure within the upper esophageal sphincter of a patient in order relieve an impact of an abnormal or defective upper esophageal sphincter anatomy, physiology, or functionality. In one implementation, the compression device is used in conjunction with an external pressure sensing device to determine the external pressure that is to be applied to the cricoid for a specific patient. The compression device can be a means for the management and/or treatment of abnormal upper esophageal sphincter functionality, or a means for strengthening an esophageal sphincter of a subject, or a means for curing esophageal reflux disease of a subject, or a means for improving vocal function in a subject, or a means for managing lung aspiration, or a means for applying cricoid pressure during anesthesia intubation, or a means for stabilizing body structures such as during medical imaging or radiation treatment.

Abstract: The systems and methods, in one embodiment, include a convolutional neural network (CNN) model trained by a modified version of the CycleGAN process. The CNN filters ultrasound images generated by a handheld ultrasound device to generate images that are perceptually similar to images generated by a cart-based ultrasound device in terms of quality. The resulting images look sharper and less noisy compared to the original inputs. The invention is a tool within the actions menu of a mobile app. When the tool is open, users can turn filtering on and off. The users will turn filtering on to reduce noise so they can reach the right scanning spot faster. After which because of body habitus, still there might be some noise that this tool can clean up. The user can then decide to have the filtering on or off during the diagnostic process.

Abstract: An agricultural sprayer includes a hydrostatic drive system configured to rotationally drive at least some of the plurality of wheels, with the hydrostatic drive system including a hydrostatic pump. Furthermore, the sprayer includes an agricultural fluid supply system configured to supply agricultural fluid to nozzles on the sprayer, with the agricultural fluid supply system including a supply pump and a plurality of supply valves. Additionally, the sprayer includes an operator input device configured to receive to an input indicative of halting auxiliary operation of the agricultural sprayer. As such, a computing system is configured to receive the input from the operator input device. Moreover, upon receipt of the input, the computing system is configured to control an operation of the hydrostatic drive system and the agricultural fluid supply system such that the supply pump is halted, the plurality of supply valves is closed, and the hydrostatic pump is operating.

Abstract: An agricultural sprayer includes a frame and a boom assembly supported on the frame, with the boom assembly extending in a lateral direction between a first end and a second end. Furthermore, the agricultural sprayer includes a plurality of nozzles supported on the boom assembly and spaced apart from each other along the lateral direction, with the plurality of nozzles configured to dispense an agricultural fluid onto underlying plants or soil. Additionally, the agricultural sprayer includes an actuator configured move at least a portion of the boom assembly relative to the frame. Moreover, the agricultural sprayer includes an operator input device moveable along a range of motion such that a position of the operator input device along the range of motion is indicative of a selected speed at which the actuator is to move the at least the portion of the boom assembly relative to the frame.

Abstract: An agricultural system can include a product application system. A user interface can be operably coupled with the product application system. One or more sensors can be configured to capture data indicative of an object proximate to the user interface. A computing system can be communicatively coupled to the product application system and the one or more sensors. The computing system can be configured to detect an object based on the data from the one or more sensors and generate instructions for one or more components of the product application system to operate in an operational condition based on the detection of the object.

Abstract: A mounting device may include a top plate including a cone-shaped center portion, a flange coupled to the cone-shaped center portion, a number of apertures defined in the flange, and a number of fasteners engaged with the apertures to couple the top plate to a surface of a structure. The flange seals a bottom side of the top plate to the surface of the structure. The flange includes a seal coupled to the bottom of the flange. The cone-shaped center portion has a convex paraboloid shape. The flange includes at least one surface that is parallel to a surface of the structure, and a transition between the cone-shaped center portion and the flange forms an angle. The top plate has a diameter sufficient to displace a load greater than 50 pounds over the surface of the structure.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: An apparatus for ion manipulation having improved duty cycle that includes a pre-filter region and an accumulation region. The pre-filter region is configured to receive ions and perform a first ion mobility filtering operation on the ions to separate the ions into a first group of ions and a second group of ions based on mobility of the ions. The accumulation region is configured to receive the first group of ions from the pre-filter region, accumulate the first group of ions into an ion packet, and release the ion packet into an ion mobility separation region configured separate the ions based on mobility of the ions. Wherein the pre-filter region is configured to reduce the amount of ions provided to the accumulation region and increase the amount of time the accumulation region can accumulate ions.

Abstract: An agricultural sprayer includes a purge tank and first and second nozzles. Furthermore, the system includes a first valve fluidly configured to selectively permit air to flow to the first nozzle and a second valve fluidly configured to selectively permit the air to flow to the second nozzle. A computing system is configured to receive an input indicative of initiation of a purging operation and, upon receipt of the input, control an operation of a main valve to allow the air to flow through a main fluid conduit. Furthermore, the computing system is configured to monitor the air pressure associated with the purge tank and control the operation of the first and second valves during the purging operation based on the monitored air pressure.

Abstract: Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Biological effects may include upregulating and downregulating inflammatory immune response molecules within a target tissue. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths.

Abstract: An apparatus for ion manipulation having improved duty cycle includes first and second separation regions separated by a switch that alternates between guiding ions to each of the separation regions. The separation regions separate the ions based on mobility over respective time periods that at least partially overlap. The apparatus can additionally or alternatively include a pre-separation region that filters ions prior to accumulating ions, thus allowing an accumulation region to accumulate for a longer time period. The apparatus can additionally or alternatively include a plurality of gates along the separation region(s) to simultaneously filter a plurality of ion packets sequentially released into the separation region(s).

Abstract: A catheter comprising a shaft and a distal end portion extending distally from the distal end of the shaft and defining a longitudinal axis. The distal end portion comprises a proximal segment, a distal segment located distally of the proximal segment, the distal segment being displaceable relative to the proximal segment, and a force sensing mechanism that includes a proximal housing fixed within the proximal segment, a piezoelectric sensor mounted to the proximal housing and having a first portion fixedly secured to the proximal housing, and a second portion that is not fixedly secured to the proximal housing, and a distal housing fixed within the distal segment and including a projection that contacts the second portion of the piezoelectric sensor and is configured to apply an axial force to the second portion of the piezoelectric sensor upon application of an external force to the distal segment.

Abstract: An agricultural method for preventing roll-back of an agricultural vehicle may include receiving a roll-back prevention input from a speed setting device indicative of a command to increase the transmission speed of the hydrostatic transmission while a service brake of the agricultural vehicle is engaged. Further, the method may include adjusting a speed mapping for the speed setting device from a predetermined speed mapping to a roll-back speed mapping in response to the roll-back prevention input, with the roll-back speed mapping being associated with a reduced speed range. Additionally, the method may include determining a transmission control command associated with a current position of the speed setting device based on the roll-back speed mapping and controlling an operation of the hydrostatic transmission to adjust the transmission speed based at least in part on the transmission control command.

Abstract: Embodiments relate to a systems and methods for preventative irradiative dental treatment. In accordance with one embodiment, a system and method include using a radiation source to generate a radiation; using an optic disposed to accept the radiation to internally reflect he radiation at a first end; using at least one side of the optic to contact a dental hard tissue; using the optic to couple some of the radiation into the dental hard tissue; and, using a controller to control a parameter of the radiation to heat a surface of the dental hard tissue.

Abstract: A product system for an agricultural sprayer includes a product tank configured to store a volume of an agricultural product. A fill station is configured to accept the agricultural product from an off-board source. A flow assembly is fluidly coupled with the fill station and is configured to direct the agricultural product into a product tank from the conduit. A reclaim system is configured to provide the agricultural product within the flow assembly to the product tank. A computing system is communicatively coupled to the reclaim system. The computing system is configured to receive inputs indicative of activation of a fill mode, detect termination of the fill mode, and activate a reclaim mode to move the agricultural product from at least the conduit to the product tank through activation of the reclaim system.

Abstract: In one aspect, embodiments relate to a system for performing preventative dental laser treatment. The system includes, a code reader configured to read a machine readable code, a processor configured to verify the machine readable code and prevent future verification of the machine readable code, and a laser treatment system configured to perform a laser treatment, based upon the verified machine readable code. The laser treatment system includes a laser arrangement configured to generate a laser beam, an optical arrangement configured to direct the laser beam toward a dental hard tissue, and a laser controller configured to control a parameter of the laser beam in order to heat at least a portion of a surface of the dental hard tissue to a temperature above 400° Celsius.

Abstract: In one implementation, a mobility-based ion separation system includes a first ion channel extending between a first end and a second end, and configured to receive an ion packet. The separation system includes a controller configured to apply a first voltage signal and a second voltage signal to a first plurality of electrodes adjacent to the first ion channel. The first plurality of electrodes are configured to generate, based on receipt of the first voltage signal, a first traveling drive potential that travels at a first speed along a first direction, the first direction extending from the first end to the second end. The first plurality of electrodes are configured to generate, based on receipt of the second voltage signal, a second DC potential decreasing along a second direction, the second direction extending from the second end to the first end.

Abstract: In one aspect, embodiments relate to a system for preventative dental laser treatment that ensures even irradiation of a laser beam. The system includes, a laser arrangement configured to generate the laser beam. The laser beam has one or more of a super-Gaussian energy profile and a transverse ring mode. The system also includes a focus optic. The focus optic is configured to converge the laser beam with a numerical aperture of 0.1 or less to a focal region. The system also includes a hand piece configured to direct the laser beam at a surface of a dental hard tissue. The system additionally includes a controller. The controller is configured to control one or more parameters of the laser source, such that a portion of the surface of the dental hard tissue is heated to a temperature in a range between 400° Celsius and 1300° Celsius.