Abstract: The present invention relates to easily replaceable rupture disk arrangements and, to arrangements including reversible calibrated rupture disk assemblies, bi-directional rupture disk assemblies and tandem pressure relief devices. The present invention further includes uses for such arrangements including apparatus and methods for preventing critical annular pressure buildup in an offshore well utilizing a modified casing portion that includes a burst disk assembly of the present invention and apparatus and methods for relieving an over-pressure in the outlet line of a positive displacement pump to prevent pump damage.