Patents by Inventor Nathaniel Beardsley

Nathaniel Beardsley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE PRODUCTION OF CARDIAC FIBROBLASTS
    Publication number: 20240139256
    Abstract: Provided herein are methods for producing quiescent cardiac fibroblast cells from pluripotent stem cells. Further provided herein are microtissue compositions comprising the cardiac fibroblast cells with endothelial cells and cardiomyocytes.
    Type: Application
    Filed: October 2, 2023
    Publication date: May 2, 2024
    Applicants: FUJIFILM Cellular Dynamics, Inc., FUJIFILM Holdings America Corporation
    Inventors: Sarah HIMMERICH, Nathaniel BEARDSLEY, Annie ARMSTRONG SMELTER, Nathan MEYER, Ravi VAIDYANATHAN, Cara RIEGER
  • APPARATUS AND METHODS FOR DELIVERY OF CELL SUSPENSION
    Publication number: 20230071939
    Abstract: Apparatus and methods for monitoring and delivering a cell suspension. In certain examples, the apparatus comprises a reservoir containing the cell suspension, a cannula, and a liquid transfer mechanism configured to transfer the cell suspension from the reservoir to the cannula. The apparatus can also comprise an agitation mechanism to agitate the cell suspension, and a monitoring device to quantify a concentration of cells transferred from the reservoir to the cannula.
    Type: Application
    Filed: February 2, 2021
    Publication date: March 9, 2023
    Applicant: FUJIFILM Cellular Dynamics, Inc.
    Inventors: Randall D. LEARISH, Nathaniel A. BEARDSLEY, Sho SATO, Christopher W. McMAHON
  • Cardiomyocyte production
    Patent number: 10604739
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: March 31, 2020
    Assignee: FUJIFILM Cellular Dynamics, Inc.
    Inventors: Casey Stankewicz, Matt Riley, Nathaniel Beardsley, Wen Bo Wang, Peter Fuhrken, Steven Kattman
  • Cardiomyocyte production
    Patent number: 9957482
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: May 1, 2018
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Casey Stankewicz, Matt Riley, Nathaniel Beardsley, Wen Bo Wang, Peter Fuhrken, Steven Kattman
  • CARDIOMYOCYTE PRODUCTION
    Publication number: 20170226481
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Application
    Filed: April 27, 2017
    Publication date: August 10, 2017
    Applicant: Cellular Dynamics International, Inc.
    Inventors: Casey STANKEWICZ, Matt RILEY, Nathaniel BEARDSLEY, Wen Bo WANG, Peter FUHRKEN, Steven KATTMAN
  • Cardiomyocyte production
    Patent number: 9365827
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: June 14, 2016
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Casey Stankewicz, Matt Riley, Nathaniel Beardsley, Wen Bo Wang, Peter Fuhrken, Steven Kattman
  • CARDIOMYOCYTE PRODUCTION
    Publication number: 20150191697
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Application
    Filed: March 23, 2015
    Publication date: July 9, 2015
    Applicant: CELLULAR DYNAMICS INTERNATIONAL, INC.
    Inventors: Casey STANKEWICZ, Matt RILEY, Nathaniel BEARDSLEY, Wen Bo WANG, Peter FUHRKEN, Steven KATTMAN
  • Automated method and apparatus for embryonic stem cell culture
    Patent number: 8815585
    Abstract: The invention concerns methods for automated culture of embryonic stem cells (ESCs) such as human ESCs. In some aspects, methods of the invention employ optimized culture media and limited proteolytic treatment of cells to separate cell clusters for expansion. Automated systems for passage and expansion of ESCs are also provided.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: August 26, 2014
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Nathaniel Beardsley, Veit Bergendahl, Megan Fitzgerald, Christine Daigh
  • AUTOMATED METHOD AND APPARATUS FOR EMBRYONIC STEM CELL CULTURE
    Publication number: 20130316445
    Abstract: The invention concerns methods for automated culture of embryonic stem cells (ESCs) such as human ESCs. In some aspects, methods of the invention employ optimized culture media and limited proteolytic treatment of cells to separate cell clusters for expansion. Automated systems for passage and expansion of ESCs are also provided.
    Type: Application
    Filed: March 19, 2013
    Publication date: November 28, 2013
    Applicant: Cellular Dynamics International, Inc.
    Inventors: Nathaniel BEARDSLEY, Veit BERGENDAHL, Megan FITZGERALD, Christine DAIGH
  • Cardiomyocyte production
    Patent number: 8415155
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: April 9, 2013
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Casey Stankewicz, Matt Riley, Nathaniel Beardsley, Wen Bo Wang, Peter Fuhrken, Steven Kattman
  • CARDIOMYOCYTE PRODUCTION
    Publication number: 20110097799
    Abstract: Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
    Type: Application
    Filed: October 19, 2010
    Publication date: April 28, 2011
    Inventors: Casey Stankewicz, Matt Riley, Nathaniel Beardsley, Wen Bo Wang, Peter Fuhrken, Steven Kattman
  • AUTOMATED METHOD AND APPARATUS FOR EMBRYONIC STEM CELL CULTURE
    Publication number: 20090029462
    Abstract: The invention concerns methods for automated culture of embryonic stem cells (ESCs) such as human ESCs. In some aspects, methods of the invention employ optimized culture media and limited proteolytic treatment of cells to separate cell clusters for expansion. Automated systems for passage and expansion of ESCs are also provided.
    Type: Application
    Filed: June 30, 2008
    Publication date: January 29, 2009
    Inventors: Nathaniel Beardsley, Veit Bergendahl, Megan Fitzgerald, Christine Daigh