Abstract: A solid photonic band gap fiber includes: a core area located at a central portion of a cross-section with respect to a longitudinal direction of the fiber, the core area being formed of a solid substance having a low refractive index; cladding areas having base portions formed of a solid substance having a low refractive index, the cladding areas surrounding the core area; and a plurality of fine high refractive index scatterers provided in the cladding areas, and disposed in a dispersed manner so as to surround the core area, the number of fine high refractive index scatterers being formed of a solid substance having a high refractive index, wherein in a state that the solid photonic band gap fiber is held at a predetermined bending radius, propagation in a high-order mode is suppressed by using a difference in a bending loss between a fundamental mode and the high-order mode, and only the fundamental mode is substantially propagated, the fundamental mode and the high-order mode being caused by bending.

Abstract: The present invention relates to methods for producing an optically active amine compound via a highly enantioselective hydrogenation reaction of an imine compound, wherein the imine compound is hydrogenated using a ruthenium metal complex having high catalytic activity and represented by Formula (1) RuXYAB??(1) such as RuBr2[(S,S)-xylskewphos][(S,S)-dpen].

Abstract: The present invention provides a composition for regenerating cartilage or treating a cartilage disease containing a monovalent metal salt of alginic acid for which the endotoxin level thereof has been lowered to an extent that does not substantially induce inflammation or fever. As a result, it is possible to provide a composition for regenerating cartilage that improves cartilage regenerative action and ease of application to a cartilage injury lesion, and a composition for treating a cartilage disease, which has the effects of protecting cartilage from mechanical irritation, inhibiting degenerative changes in cartilage caused by wear and inflammation, repairing a cartilage injury lesion, and inhibiting inflammation and pain of joint tissue.