Patents by Inventor Nei Yoshida

Nei Yoshida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of testing for bronchial asthma
    Patent number: 7160683
    Abstract: SCCA1 and SCCA2 genes, whose expression were greatly changed in a plurality of cells by stimulating respiratory tract epithelial cells with IL-4 or IL-13, were obtained as allergy related genes. Furthermore, elevation of blood level of expression products of these genes accompanying bronchial asthmatic attack was elucidated. This invention provides a method of testing for bronchial asthmatic attack that uses as indicators, expression levels of these genes in biological samples.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: January 9, 2007
    Assignee: Genox Research, Inc.
    Inventors: Noriko Ohtani, Keiko Matsui, Nei Yoshida, Yuji Sugita, Yuhei Hamasaki, Kenji Izuhara
  • Pollen allergy-related gene 513
    Patent number: 6986990
    Abstract: T cells from multiple subjects who showed different cedar pollen specific IgE titers were prepared before and after cedar pollen dispersal, and differential display analysis was performed to screen for pollen antigen responsive genes. As a result, a novel gene was successfully isolated whose expression is significantly higher in subjects with high cedar pollen specific IgE titer. The inventors have found that it is possible to use this gene to test for an allergic disease and to screen for candidate compounds for therapeutic drugs for an allergic disease.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: January 17, 2006
    Assignee: Genox Research, Inc.
    Inventors: Takeshi Nagasu, Yuji Sugita, Tomoko Fujishima, Tadahiro Oshida, Masaya Obayashi, Shigemichi Gunji, Izumi Obayashi, Yukiho Imai, Nei Yoshida, Kaoru Ogawa, Keiko Matsui
  • Method of testing for allergic diseases
    Publication number: 20030224423
    Abstract: B1799 gene, whose expression level increases significantly in the patient group, was successfully identified by screening for a gene which shows difference in expression in blood collected from multiple healthy subjects and patients of allergic diseases employing the differential display method. The gene expression level is specifically high in T cells and increased due to T cell activation. This gene can be used in testing for allergic diseases and also in screening for therapeutic agents for allergic diseases.
    Type: Application
    Filed: April 3, 2003
    Publication date: December 4, 2003
    Applicants: Genox Research, Inc., Japan as Represented by General Director of Agency of National Center for Child Health & Development
    Inventors: Yoshiko Matsumoto, Yukiho Imai, Nei Yoshida, Tadahiro Oshida, Yuji Sugita, Hirohisa Saito
  • Method of examining allergic disease
    Publication number: 20030152956
    Abstract: Six genes, whose expressions were greatly changed in a plurality of cells by stimulating respiratory tract epithelial cells with IL-4 or IL-13, were obtained as allergy related genes. This invention provides a method of testing for allergic diseases, and method of screening for compounds useful in treating such diseases, that use as indicators, expression levels of these genes in biological samples.
    Type: Application
    Filed: December 9, 2002
    Publication date: August 14, 2003
    Inventors: Noriko Ohtani, Keiko Matsui, Nei Yoshida, Yuji Sugita, Kenji Izuhara
  • Method for testing for allergic disease
    Publication number: 20030148312
    Abstract: An objective of the present invention is to provide a method for testing for an allergic disease and a method of screening for a therapeutic agent for allergic diseases.
    Type: Application
    Filed: July 24, 2002
    Publication date: August 7, 2003
    Applicant: NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT
    Inventors: Nei Yoshida, Naoko Nagata, Tadahiro Oshida, Ryoichi Hashida, Yuji Sugita, Hirohisa Saito
  • Method of testing for bronchial asthma
    Publication number: 20030099979
    Abstract: SCCA1 and SCCA2 genes, whose expression were greatly changed in a plurality of cells by stimulating respiratory tract epithelial cells with IL-4 or IL-13, were obtained as allergy related genes. Furthermore, elevation of blood level of expression products of these genes accompanying bronchial asthmatic attack was elucidated. This invention provides a method of testing for bronchial asthmatic attack that uses as indicators, expression levels of these genes in biological samples.
    Type: Application
    Filed: August 7, 2002
    Publication date: May 29, 2003
    Applicant: GENOX RESEARCH, INC.
    Inventors: Noriko Ohtani, Keiko Matsui, Nei Yoshida, Yuji Sugita, Yuhei Hamasaki, Kenji Izuhara