Patents by Inventor Neil Berkley

Neil Berkley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Minicell based delivery of biologically active compounds
    Patent number: 9670270
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: June 6, 2017
    Assignee: Vaxiion Therapeutics, LLC
    Inventors: Roger Sabbadini, Neil Berkley, Mark Surber, Robert Klepper
  • MINICELL BASED DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20150218254
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: April 22, 2015
    Publication date: August 6, 2015
    Inventors: Roger Sabbadini, Neil Berkley, Mark Surber, Robert Klepper
  • Minicell based delivery of biologically active compounds
    Patent number: 9017986
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: April 28, 2015
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger Sabbadini, Neil Berkley, Mark Surber, Robert Klepper
  • MINICELL BASED DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20130337545
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: August 1, 2013
    Publication date: December 19, 2013
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: ROGER SABBADINI, Neil Berkley, Mark Surber, Robert Klepper
  • Immunogenic minicells and methods of use
    Patent number: 8524484
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: September 3, 2013
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Matthew J. Giacalone
  • IMMUNOGENIC MINICELLS AND METHODS OF USE
    Publication number: 20120252099
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Application
    Filed: March 5, 2012
    Publication date: October 4, 2012
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Matthew J. Giacalone
  • Use of Aerosolized Antibiotics for Treating Chronic Obstructive Pulmonary Disease
    Publication number: 20120237564
    Abstract: The present invention relates to methods and compositions for treating obstructive pulmonary disorders. In particular, compositions and methods described herein relate to the use of an aerosolized antibiotic for treating obstructive pulmonary disorders including chronic obstructive pulmonary disorder (COPD) and chronic bronchitis (CB).
    Type: Application
    Filed: February 16, 2012
    Publication date: September 20, 2012
    Applicant: MPEX Pharmaceuticals, Inc.
    Inventors: Michael N. Dudley, Neil Berkley, David C. Griffith, Jeffery S. Loutit, Elizabeth E. Morgan, Keith A. Bostian, Sanjay Sethi
  • MINICELL BASED DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20120142079
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: November 11, 2011
    Publication date: June 7, 2012
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Robert Klepper
  • MINICELL BASED DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20120135503
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: November 11, 2011
    Publication date: May 31, 2012
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Immunogenic minicells and methods of use
    Patent number: 8129166
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: March 6, 2012
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark Surber
  • Minicells displaying antibodies or derivatives thereof and comprising biologically active compounds
    Patent number: 8101396
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: January 24, 2012
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber, Robert Klepper
  • MINICELLS EXPRESSING ANTIBODIES OR DERIVATIVES THEREOF AND COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20110281330
    Abstract: Minicells are used to deliver biologically active compounds including radioisotopes, polypeptides, nucleic acids, small molecules, drug molecules, and chemotherapeutic agents. In some cases, the minicell displays ligands or binding moieties that target the minicell to a desired host cell.
    Type: Application
    Filed: March 16, 2007
    Publication date: November 17, 2011
    Applicant: VAXIION THERAPEUTICS, INC.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections
    Patent number: 7994225
    Abstract: Efflux pump inhibitors are co-administered with antimicrobial agents for the treatment of ophthalmic or otic infections. The agents may be co-administered directly to the site of infection (e.g., the eye or ear).
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: August 9, 2011
    Assignee: Rempex Pharmaceuticals, Inc.
    Inventors: Keith Bostian, Tomasz Glinka, Olga Lomovskaya, Mark Surber, Neil Berkley, David Griffith
  • Rhamnose-inducible expression constructs and methods
    Patent number: 7871815
    Abstract: Disclosed herein is a rhamnose-inducible expression vector.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: January 18, 2011
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • IMMUNOGENIC MINICELLS AND METHODS OF USE
    Publication number: 20090011490
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Application
    Filed: June 4, 2008
    Publication date: January 8, 2009
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark Surber
  • MINICELLS AS VACCINES
    Publication number: 20090004744
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Application
    Filed: April 30, 2008
    Publication date: January 1, 2009
    Applicant: Vaxiion Therapeutics, Inc.
    Inventors: Mark W. Surber, Roger Sabbadini, Neil Berkley
  • Immunogenic minicells and methods of use
    Patent number: 7396822
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: July 8, 2008
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark Surber
  • BACTERIAL EFFLUX PUMP INHIBITORS FOR THE TREATMENT OF OPHTHALMIC AND OTIC INFECTIONS
    Publication number: 20080132457
    Abstract: Efflux pump inhibitors are co-administered with antimicrobial agents for the treatment of ophthalmic or otic infections. The agents may be co-administered directly to the site of infection (e.g., the eye or ear).
    Type: Application
    Filed: September 17, 2007
    Publication date: June 5, 2008
    Inventors: Keith Bostian, Thomasz Glinka, Olga Lomovskaya, Mark Surber, Neil Berkley, David Griffith
  • Eubacterial minicells and their use as vectors for nucleic acid delivery and expression
    Patent number: 7183105
    Abstract: Th invention provides compositions and methods for the production of achromosomal and anucleate cells useful for applications such as diagnositic and therapeutic uses, as well as research tools and agents for drug discovery.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: February 27, 2007
    Assignee: Vaxiion Therapeutics, Inc.
    Inventors: Roger A. Sabbadini, Neil Berkley, Mark W. Surber
  • Minicells as vaccines
    Publication number: 20060002956
    Abstract: The disclosed invention relates to immunogenic minicells cells (anucleated) and their use to induce an immune response from a subject.
    Type: Application
    Filed: April 1, 2005
    Publication date: January 5, 2006
    Inventors: Mark Surber, Roger Sabbadini, Neil Berkley