Patents by Inventor Neil H. Bander

Neil H. Bander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced reverse transcriptase polymerase chain assay to detect MN in patients with renal cell carcinoma
    Patent number: 6087098
    Abstract: This invention provides methods of (a) diagnosing; (b) determining the stage of; and (c) monitoring the effect of a therapeutic intervention for a renal cell carcinoma in a human subject which comprises detecting the expression of the MN gene. In one embodiment, the method is directed to detection of the renal cell carcinoma known as clear cell carcinoma. In another embodiment, the method is used as a peripheral blood assay. In another embodiment, the method is a polymerase chain reaction assay for amplifying and detecting the presence of the cDNA molecule encoding the MN protein.
    Type: Grant
    Filed: April 15, 1997
    Date of Patent: July 11, 2000
    Assignees: The Trustees of Columbia University in the City of New York, Cornell Research Foundation, Inc.
    Inventors: James M. McKiernan, Ihor S. Sawczuk, Ralph Buttyan, Neil H. Bander
  • Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood
    Patent number: 5773292
    Abstract: The present invention is directed to the use of antibodies or binding portions thereof or probes which recognize an antigen of normal, benign, hyperplastic, and cancerous prostate epithelial cells or portions thereof. These antibodies or binding portions thereof or probes can be labeled and used for detection of such cells. They also can be used alone or bound to a substance effective to ablate or kill such cells as a therapy for prostate cancer. Also disclosed is a hybridoma cell line which produces a monoclonal antibody recognizing antigens of normal, benign, hyperplastic, and cancerous prostate epithelial cells or portions thereof.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 30, 1998
    Assignee: Cornell University
    Inventor: Neil H. Bander
  • Method to detect sensitivity to alpha-interferon therapy
    Patent number: 5145773
    Abstract: This invention provides a method of detecting sensitivity to alpha-interferon therapy which comprises contacting a sample with a monoclonal antibody under conditions so as to form an antibody-antigen complex, detecting the complex so formed, and thereby detecting sensitivity to alpha-interferon.
    Type: Grant
    Filed: May 25, 1989
    Date of Patent: September 8, 1992
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Anthony P. Albino, David M. Nanus, Neil H. Bander, Lawrence M. Pfeffer
  • Method for characterizing types of renal carcinoma and prognosis
    Patent number: 4935344
    Abstract: Antigenic profiles of renal carcinoma specimans developed with panels of monoclonal antibodies derived from several different tissues serve as useful clinical indicators for cancer type, cancer subset as well as histiogenesis and prognosis indicators.
    Type: Grant
    Filed: March 7, 1986
    Date of Patent: June 19, 1990
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Neil H. Bander, Carlos Cordon-Cardo, Connie L. Finstad, Willet F. Whitmore, Myron R. Melamed, Herbert F. Oettgen, Lloyd J. Old
  • Monoclonal antibody panel for early diagnosis and therapy of renal carcinoma
    Patent number: 4713352
    Abstract: A panel of monoclonal antibodies is developed for use in diagnosis and treatment of renal carcinoma. One monoclonal antibody F.sub.31 reacts with 80% of renal carcinoma. The area of overlap of reactivity of monoclonal antibodies F.sub.31, F.sub.23, S.sub.4, S.sub.23 and S.sub.27 is the site of origin of most renal carcinomas. Reactivity with this panel of monoclonal antibodies localizes most renal carcinoma and is a vehicle for early diagnosis and treatment.
    Type: Grant
    Filed: May 4, 1984
    Date of Patent: December 15, 1987
    Assignee: Sloan-Kettering Institute for Cancer Reseach
    Inventors: Neil H. Bander, Willet F. Whitmore, Lloyd J. Old