Abstract: Described herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof and solvates of any of the foregoing capable of inhibiting protein kinase A and/or its mutants, pharmaceutical compositions comprising at least one of the compounds, pharmaceutically acceptable salts thereof, and solvates of any of the foregoing, processes for making the compounds, pharmaceutically acceptable salts thereof, and solvates of any of the foregoing, and methods of using the same.

Abstract: An apparatus is disclosed that includes a switchable optical filter having a layer of switchable material; a light source providing light of a wavelength that causes the switchable material to transition from a faded state to a dark state, or a dark state to a faded state; and a switch for controlling activation of the light source.

Abstract: Described herein is a laminate electrochemical cell including a cathode layer, an anode layer, a polymer electrolyte layer, and a ceramic layer. The polymer electrode layer is arranged between the cathode layer and the anode layer and coats at least a portion of the anode layer. The ceramic layer is arranged between the polymer electrolyte layer and the cathode layer. The ceramic layer and the polymer electrolyte layer have different compositions. Also described herein are methods of manufacturing the laminate electrochemical cell, battery stacks including a plurality of said laminate electrochemical cells, and electrically-powered devices including the electrochemical cell or battery stack.

Abstract: A composite cathode material includes a gel polymer electrolyte and particles of a cathode material. The particles of the cathode material are arranged in the gel polymer electrolyte.

Abstract: A variable loss attenuator is provided. Two or more controllable stages each include a differential or single-ended ? network. Each ? network includes one or more series elements connected in series between the signal input and the signal output. Each series element includes a series transistor, which may potentially be provided without an inductor in parallel. Each ? network includes a plurality of shunt elements each including at least one respective shunt transistor. An input stage connects to the first controllable stage and an output stage connects from the last controllable stage. Intermediate stages connect the controllable stages to one another. Each of the input stage, output stage, and intermediate stages include a right-handed transmission line component and coupled between the signal input and a first one of the controllable stages. Shunt inductors are located at inputs and outputs of each of the controllable stages.

Abstract: A standing wave oscillator is described. The standing wave oscillator includes a transmission line, and an even number of gain stages. Each gain stage is connected to the transmission line, and each gain stage is located at a respective location along a length of the transmission line. The gain stages are configured to generate a standing wave oscillator signal along the length of the transmission line, when a supply voltage is applied to at least one end of the transmission line. The location of each gain stage is non-coincidental with an expected location of maximum amplitude of the standing wave oscillator signal.

Abstract: A variable loss attenuator is provided. Two or more controllable stages each include a differential or single-ended ? network. Each ? network includes one or more series elements connected in series between the signal input and the signal output. Each series element includes a series transistor, which may potentially be provided without an inductor in parallel. Each ? network includes a plurality of shunt elements each including at least one respective shunt transistor. An input stage connects to the first controllable stage and an output stage connects from the last controllable stage. Intermediate stages connect the controllable stages to one another. Each of the input stage, output stage, and intermediate stages include a right-handed transmission line component and coupled between the signal input and a first one of the controllable stages. Shunt inductors are located at inputs and outputs of each of the controllable stages.

Abstract: A standing wave oscillator is described. The standing wave oscillator includes a transmission line, and an even number of gain stages. Each gain stage is connected to the transmission line, and each gain stage is located at a respective location along a length of the transmission line. The gain stages are configured to generate a standing wave oscillator signal along the length of the transmission line, when a supply voltage is applied to at least one end of the transmission line. The location of each gain stage is non-coincidental with an expected location of maximum amplitude of the standing wave oscillator signal.

Abstract: A control circuit is disclosed for controlling operation of a radio frequency (RF) transistor. The control circuit has a first sub-circuit that accepts a reference voltage and a reference current. The control circuit has a second sub-circuit with a plurality of stacked transistors coupled between the first sub-circuit and ground, and a resistor ladder coupled between the first sub-circuit and an output port of the control circuit. The first sub-circuit provides the reference current to flow through the stacked transistors, and sets a total voltage drop across the stacked transistors equal to the reference voltage. The first sub-circuit also sets a total voltage drop across the resistor ladder equal to the reference voltage. Each rung of the resistor ladder is coupled to control an operating voltage of a stacked transistor, to cause each stacked transistor to operate with similar control conditions.

Abstract: Hybrid variable gain amplifiers and methods of controlling hybrid VGAs are disclosed. The hybrid VGA includes a first portion that provides a current path between a positive input and a positive output, and a current path either between the positive input and a negative output, in a first mode of operation, or between the positive input and a voltage source, in a second mode of operation. A second portion of the VGA provides a current path between a negative input and the negative output, and a current path either between the negative input and the positive output, in the first mode of operation, or between the negative input and the voltage source, in the second mode of operation. Control voltages selectively enable the paths in the first or second mode of operation. The control voltages further control amount of current flow in the enabled paths.

Abstract: Hybrid variable gain amplifiers and methods of controlling hybrid VGAs are disclosed. The hybrid VGA includes a first portion that provides a current path between a positive input and a positive output, and a current path either between the positive input and a negative output, in a first mode of operation, or between the positive input and a voltage source, in a second mode of operation. A second portion of the VGA provides a current path between a negative input and the negative output, and a current path either between the negative input and the positive output, in the first mode of operation, or between the negative input and the voltage source, in the second mode of operation. Control voltages selectively enable the paths in the first or second mode of operation. The control voltages further control amount of current flow in the enabled paths.

Abstract: A control circuit is disclosed for controlling operation of a radio frequency (RF) transistor. The control circuit has a first sub-circuit that accepts a reference voltage and a reference current. The control circuit has a second sub-circuit with a plurality of stacked transistors coupled between the first sub-circuit and ground, and a resistor ladder coupled between the first sub-circuit and an output port of the control circuit. The first sub-circuit provides the reference current to flow through the stacked transistors, and sets a total voltage drop across the stacked transistors equal to the reference voltage. The first sub-circuit also sets a total voltage drop across the resistor ladder equal to the reference voltage. Each rung of the resistor ladder is coupled to control an operating voltage of a stacked transistor, to cause each stacked transistor to operate with similar control conditions.

Abstract: The aerosol delivery system is comprised of a strap forming a loop, and an aerosol container placement region formed in the loop by securing the loop together at two points therealong. It is essentially a “figure 8” shape with a loop in the center. When pressure is applied to the loop by pulling the ends away from each other, it causes tension in the center loop, thereby applying pressure to the inserted aerosol can and activating the pressure mechanism in the can to expel whatever product is in the can.

Abstract: A method of spraying a posterior portion of a human person includes disposing an aerosol container in an aerosol container receiving bay of a strap-based aerosol delivery assembly. The aerosol container has product therein and a dispensing button. The aerosol delivery assembly includes: the aerosol container receiving bay having a fixed length perimeter; left and right grip sections disposed on opposing lateral sides of the aerosol container receiving bay. The method includes disposing the aerosol delivery assembly such that the aerosol container receiving bay is disposed posteriorly relative to the person, and while so positioned, dispensing product from the aerosol container toward the person's posterior by pulling the left and right grip sections away from each other, so that a vertical height of the aerosol container receiving bay is decreased to thereby depress the dispensing button of the aerosol container. Related assemblies are also disclosed.

Abstract: The aerosol delivery system is comprised of a strap forming a loop, and an aerosol container placement region formed in the loop by securing the loop together at two points therealong. It is essentially a “figure 8” shape with a loop in the center. When pressure is applied to the loop by pulling the ends away from each other, it causes tension in the center loop, thereby applying pressure to the inserted aerosol can and activating the pressure mechanism in the can to expel whatever product is in the can.

Abstract: The present invention improves the bad taste of injected anesthetics and analgesics by incorporating a flavoring or cooling agent such as menthol into the parenteral composition.

Abstract: The use of additives to stabilize DHA when compressed into tablets, or filled as a powder into capsules, for oral administration.

Abstract: The use of additives to stabilize DHA when compressed into tablets, or filled as a powder into capsules, for oral administration.

Abstract: The use of additives to stabilize DHA when compressed into tablets, or filled as a powder into capsules, for oral administration.

Abstract: The invention relates to a system and method which allows the performance of an organization to be assessed with respect to data which is generated by the organization. The invention provides for the collation of data representing a number of functions of the organization, and, if necessary reformatting the same, and then processing of the same to generate results to represent the actual activities of the organisation or parts thereof and typically allow comparison with target valves.