Abstract: Systems and methods for rapid importation of data including temporally tracked object recognition. One of the methods includes receiving a request to authorize a prescription for a patient, the request being from a medical professional and the request being received of a network. The request is determined to be approved based on information associated with the patient. Transaction information is generated that is associated with the prescription, the transaction information specifying that the patient is authorized to obtain an associated pharmaceutical, and the transaction information being included in a transaction record associated with the patient. Authorization information associated with the prescription is generated, the authorization information being provided to a user device of the patient, and the authorization information enabling confirmation by an outside system that the prescription is authorized.

Abstract: Systems and methods for rapid importation of data including temporally tracked object recognition. One of the methods includes receiving a request to authorize a prescription for a patient, the request being from a medical professional and the request being received of a network. The request is determined to be approved based on information associated with the patient. Transaction information is generated that is associated with the prescription, the transaction information specifying that the patient is authorized to obtain an associated pharmaceutical, and the transaction information being included in a transaction record associated with the patient. Authorization information associated with the prescription is generated, the authorization information being provided to a user device of the patient, and the authorization information enabling confirmation by an outside system that the prescription is authorized.

Abstract: The present disclosure provides methods of treating polycystic ovary syndrome (PCOS) with tetrahydro-iso-alpha acid (THIAA) derivatives and substantially enantiomerically pure compositions and pharmaceutical formulations thereof, in particular KDT500 and KDT501.

Abstract: Systems and methods for rapid importation of data including temporally tracked object recognition. One of the methods includes receiving a request to authorize a prescription for a patient, the request being from a medical professional and the request being received of a network. The request is determined to be approved based on information associated with the patient. Transaction information is generated that is associated with the prescription, the transaction information specifying that the patient is authorized to obtain an associated pharmaceutical, and the transaction information being included in a transaction record associated with the patient. Authorization information associated with the prescription is generated, the authorization information being provided to a user device of the patient, and the authorization information enabling confirmation by an outside system that the prescription is authorized.

Abstract: (R*,R*)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol (Tramadol) is synthesized in a Grignard reaction in the presence of an additive resulting in a higher trans:cis ratio of product than is obtained in the absence of the additive. The Grignard reaction between 3 bromoanisole and the appropriate Mannich base in the presence of an amine or ether additive gives the amine product in an improved trans/cis ratio. The base is converted to its hydrochloride and recrystallized from a low molecular weight nitrile such as acetonitrile until a greater than 98% trans/cis ratio is obtained. Recrystallization from isopropanol gives (R*,R*)2-[(dimethylamino)methyl]-1-(3-metboxyphenyl)cyclohexanol hydrochloride free of the nitrile solvent. A hydrochloride of Tramadol can be synthesized without increasing a ratio of trans:cis by including a step in which HCl is added to Tramadol base in the presence of toluene.