Patents by Inventor Nellithanath Thankachen Byju

Nellithanath Thankachen Byju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-thrombotic compounds
    Patent number: 10105353
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: October 23, 2018
    Assignee: IPCA LABORATORIES LIMITED
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki Moje
  • Methods for the treatment or prophylaxis of thrombosis or embolism
    Patent number: 9321785
    Abstract: The present invention relates to a method of ameliorating the drawbacks of anti-platelet drug named clopidogrel. The method of the present invention comprises administration of an (S)oxo-clopidogrel or its derivative of the Formula IIA in its free or pharmaceutically acceptable salt form for alleviating the symptoms of thrombosis or embolism by inhibiting blood platelet aggregation. Compositions for use in such methods are also provided.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: April 26, 2016
    Assignee: IPCA Laboratories Limited
    Inventors: Ashok Kumar, Nellithanath Thankachen Byju
  • COMPOSITION FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM
    Publication number: 20150307513
    Abstract: The description herein relates to a method of ameliorating the drawbacks of anti-platelet drug named clopidogrel. The method of the description herein comprises administration of an acyl derivative of the Formula IIA in its free or pharmaceutically acceptable salt form for alleviating the symptoms of thrombosis or embolism by inhibiting blood platelet aggregation. Compositions for use in such methods are also provided.
    Type: Application
    Filed: July 8, 2015
    Publication date: October 29, 2015
    Inventors: Ashok KUMAR, Nellithanath Thankachen Byju
  • Anti-Thrombotic Compounds
    Publication number: 20140038924
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Application
    Filed: October 3, 2013
    Publication date: February 6, 2014
    Applicant: IPCA LABORATORIES LIMITED
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki MOJE
  • Anti-Thrombotic Compounds
    Publication number: 20140031320
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Application
    Filed: October 3, 2013
    Publication date: January 30, 2014
    Applicant: IPCA LABORATORIES LIMITED
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki MOJE
  • METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM
    Publication number: 20140018331
    Abstract: The present invention relates to a method of ameliorating the drawbacks of anti-platelet drug named clopidogrel. The method of the present invention comprises administration of an (S)oxo-clopidogrel or its derivative of the Formula IIA in its free or pharmaceutically acceptable salt form for alleviating the symptoms of thrombosis or embolism by inhibiting blood platelet aggregation. Compositions for use in such methods are also provided.
    Type: Application
    Filed: August 7, 2013
    Publication date: January 16, 2014
    Applicant: IPCA Laboratories Limited
    Inventors: Ashok KUMAR, Nellithanath Thankachen Byju
  • Anti-Thrombotic Compounds
    Publication number: 20130316987
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Application
    Filed: August 1, 2013
    Publication date: November 28, 2013
    Applicant: IPCA LABORATORIES LIMITED
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki MOJE
  • Anti-Thrombotic Compounds
    Publication number: 20130316986
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Application
    Filed: August 1, 2013
    Publication date: November 28, 2013
    Applicant: IPCA LABORATORIES LIMITED
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki MOJE
  • Methods for the treatment or prophylaxis of thrombosis or embolism
    Patent number: 8541422
    Abstract: The present invention relates to a method of ameliorating the drawbacks of anti-platelet drug named clopidogrel. The method of the present invention comprises administration of an (S)oxo-clopidogrel or its derivative of the Formula IIA in its free or pharmaceutically acceptable salt form for alleviating the symptoms of thrombosis or embolism by inhibiting blood platelet aggregation. Compositions for use in such methods are also provided.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: September 24, 2013
    Assignee: IPCA Laboratories Limited
    Inventors: Ashok Kumar, Nellithanath Thankachen Byju
  • Solid forms of methyl (7aS,2?S)-2-(2-chlorophenyl)-2-(2,4,5,6,7,7a-hexahydrothieno[3,2-c]-5-pyridin-2-one)acetate
    Patent number: 8536337
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: September 17, 2013
    Assignee: IPCA Laboratories Limited
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki Moje
  • ANTI-THROMBOTIC COMPOUNDS
    Publication number: 20120329763
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Application
    Filed: March 23, 2012
    Publication date: December 27, 2012
    Inventors: Ashok KUMAR, Satish Rajanikant SOUDAGAR, Nellithanath Thankachen BYJU, Gaurav SAHAL, Arpana Prashant MATHUR, Sanjay Pandurang GAWADE, Dinesh Kanji BHADRA, Devki MOJE
  • ANTI-THROMBOTIC COMPOUNDS
    Publication number: 20120329762
    Abstract: New compounds, namely, (7aS,2?S)-2-oxoclopidogrel and its pharmaceutically acceptable salts thereof are disclosed for treatment or prophylaxis of thrombo-embolism and/or cardiovascular diseases.
    Type: Application
    Filed: January 6, 2012
    Publication date: December 27, 2012
    Inventors: Ashok Kumar, Satish Rajanikant Soudagar, Nellithanath Thankachen Byju, Gaurav Sahal, Arpana Prashant Mathur, Sanjay Pandurang Gawade, Dinesh Kanji Bhadra, Devki Moje
  • METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM
    Publication number: 20120053157
    Abstract: The present invention relates to a method of ameliorating the drawbacks of anti-platelet drug named clopidogrel. The method of the present invention comprises administration of an (S)oxo-clopidogrel or its derivative of the Formula IIA in its free or pharmaceutically acceptable salt form for alleviating the symptoms of thrombosis or embolism by inhibiting blood platelet aggregation. Compositions for use in such methods are also provided.
    Type: Application
    Filed: August 26, 2011
    Publication date: March 1, 2012
    Applicant: IPCA LABORATORIES LIMITED
    Inventors: Ashok Kumar, Nellithanath Thankachen Byju
  • Process for preparation of atovaquone and novel intermediates thereof
    Patent number: 7847127
    Abstract: Disclosed herein is a novel process for preparation of atovaquone. The process includes reacting 1,4-naphthoquinone with trans-4-(4-chlorophenyl) cyclohexane carboxylic acid followed by halogenation to obtain a dihalo-compound. Further, dehydrohalogenation of the dihalo-compound produces a monohalogeno-compound which under goes hydrolysis to produce atovaquone. The invention also discloses atovaquone in a substantially pure and well defined polymorphic form designated as “Form IPCA-ATO,” and the preparation thereof.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: December 7, 2010
    Assignee: IPCA Laboratories Limited
    Inventors: Ashok Kumar, Suneel Yeshwant Dike, Pramil Kumar Mathur, Nellithanath Thankachen Byju, Brajesh Sharma, Swapnil Shreekant Kore, Vitthal Suryabhan Buchude, Dharmendra Singh
  • PROCESS FOR OPTICALLY ACTIVE SULFOXIDE COMPOUNDS
    Publication number: 20100210848
    Abstract: The present invention discloses novel processes for preparing optically active sulphoxide compounds of formula I by asymmetric oxidation of prochiral sulphide compounds of Formula II. More particularly, the invention discloses processes for preparation of optically active proton pump Inhibitors (PPIs) or their optically active precursor (=intermediate) compounds (Formula I) that can be converted into pharmaceutically useful PPIs.
    Type: Application
    Filed: October 3, 2008
    Publication date: August 19, 2010
    Applicant: IPCA Laboratories Ltd.
    Inventors: Ashok Kumar, Dharmendra Singh, Nellithanath Thankachen Byju, Prasad Shankar Kadam, Harishankar Prahladkumar Vishwakarma, Vijay Ojha, Umeshkumar Suresh Ninawe
  • NEW PROCESS FOR PREPARATION OF ATOVAQUONE AND NOVEL INTERMEDIATES THEREOF
    Publication number: 20100081847
    Abstract: Disclosed herein is a novel process for preparation of atovaquone. The process includes reacting 1,4-naphthoquinone with trans-4-(4-chlorophenyl) cyclohexane carboxylic acid followed by halogenation to obtain a dihalo-compound. Further, dehydrohalogenation of the dihalo-compound produces a monohalogeno-compound which under goes hydrolysis to produce atovaquone. The invention also discloses atovaquone in a substantially pure and well defined polymorphic form designated as “Form IPCA-ATO,” and the preparation thereof.
    Type: Application
    Filed: October 21, 2009
    Publication date: April 1, 2010
    Inventors: Ashok Kumar, Suneel Yeshwant Dike, Pramilkumar Mathur, Nellithanath Thankachen Byju, Brajesh Sharma, Swapnil Shreekant Kore, Vitthal Suryabhan Buchude, Dharmendra Singh
  • NOVEL POLYMORPH OF ATOVAQUONE
    Publication number: 20090221715
    Abstract: The present invention relates to a novel polymorphic form of atovaquone. More particularly, it relates to a novel crystalline form, that has improved solubility and other bulk characteristics suitable for pharmaceutical application. The present invention also relates to processes for preparing a new polymorphic form of atovaquone and its use in industry.
    Type: Application
    Filed: February 27, 2009
    Publication date: September 3, 2009
    Inventors: Ashok Kumar, Suneel Yeshwant Dike, Pramilkumar Mathur, Nellithanath Thankachen Byju, Brajesh Sharma, Swapnil Shreekant Kore, Vitthal Suryabhan Buchude, Dharmendra Singh