Patents by Inventor Nicholas A. Mort

Nicholas A. Mort has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell adhesion-inhibiting antiinflammatory compounds
    Publication number: 20030220365
    Abstract: Compounds having Formula I 1
    Type: Application
    Filed: March 12, 2003
    Publication date: November 27, 2003
    Inventors: Andrew O. Stewart, Steven A. Boyd, David L. Arendsen, Pramila Bhatia, Kevin R. Condroski, Jennifer C. Freeman, Indrani W. Gunawardana, Gui-Dong Zhu, Kraig Lartey, Catherine M. McCarty, Nicholas A. Mort, Meena V. Patel, Michael A. Staeger, David M. Stout
  • Cell adhesion-inhibiting antiinflammatory compounds
    Patent number: 6579882
    Abstract: Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: June 17, 2003
    Assignee: Abbott Laboratories
    Inventors: Andrew O. Stewart, Steven A. Boyd, David L. Arendsen, Pramila Bhatia, Kevin R. Condroski, Jennifer C. Freeman, Indrani W. Gunawardana, Gui-Dong Zhu, Kraig Lartey, Catherine M. McCarty, Nicholas A. Mort, Meena V. Patel, Michael A. Staeger, David M. Stout
  • Cell adhesion-inhibiting antiinflammatory compounds
    Publication number: 20010020030
    Abstract: Compounds having Formula I 1
    Type: Application
    Filed: March 6, 2001
    Publication date: September 6, 2001
    Inventors: Andrew O. Stewart, Steven A. Boyd, David L. Arendsen, Pramila Bhatia, Kevin R. Condroski, Jennifer C. Freeman, Indrani W. Gunawardana, Gui-Dong Zhu, Kraig Lartey, Catherine M. McCarty, Nicholas A. Mort, Meena V. Patel, Michael A. Staeger, David M. Stout
  • Cell adhesion-inhibiting antiinflammatory compounds
    Patent number: 6232320
    Abstract: Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: May 15, 2001
    Assignee: Abbott Laboratories
    Inventors: Andrew O. Stewart, Steven A. Boyd, David L. Arendsen, Pramila Bhatia, Kevin R. Condroski, Jennifer C. Freeman, Indrani W. Gunawardana, Gui-Dong Zhu, Kraig Lartey, Catherine M. McCarty, Nicholas A. Mort, Meena V. Patel, Michael A. Staeger, David M. Stout
  • Macrolide LHRH antagonists
    Patent number: 6020521
    Abstract: Disclosed are 3'-N-desmethyl-3'-N-susbstituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythrolide A derivatives which are antagonists of luteinizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: February 1, 2000
    Assignee: Abbott Laboratories
    Inventors: John T. Randolph, Fortuna Haviv, Daryl Sauer, Philip Waid, Charles J. Nichols, Nicholas A. Mort, Christopher R. Dalton, Jonathan Greer
  • 3',3-N-bis-substituted macrolide LHRH antagonists
    Patent number: 5972898
    Abstract: Disclosed are 3',3'-N-bisdesmethyl-3',3'-N-bis-substituted-6-O-methyl-11-deoxy-11,12-cyc lic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 26, 1999
    Assignee: Abbott Laboratories
    Inventors: Daryl R. Sauer, Fortuna Haviv, John Randolph, Nicholas A. Mort, Christopher R. Dalton, Milan Bruncko, Michele A. Kaminski, Bradley W. Crawford, Lisa Marie Frey, Jonathan Greer
  • Macrolide LHRH antagonists
    Patent number: 5955440
    Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: September 21, 1999
    Assignee: Abbott Laboratories
    Inventors: Daryl R. Sauer, Fortuna Haviv, John Randolph, Nicholas A. Mort, Christopher R. Dalton, Milan Bruncko, Michele A. Kaminski, Bradley W. Crawford, Lisa Marie Frey, Jonathan Greer
  • 6-position modified decapeptide LHRH antagonists
    Patent number: 5698522
    Abstract: The present invention provides a class of decapeptide compounds which are potent antagonists of LHRH activity and which have the structure A.sup.1 -D.sup.2 -E.sup.3 -G.sup.4 -J.sup.5 -L.sup.6 -M.sup.7 -Q.sup.8 -R.sup.9 -T.sup.10. The compounds of the percent invention are characterized by having an .OMEGA.-amino-functionalized side chain on the D-aminoacyl residue at position 6. The .OMEGA.-amino group of this side chain is further derivatized by the attachment of an extending group which likewise has a terminal amino group which is capped by an acyl group.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: December 16, 1997
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Timothy D. Fitzpatrick, Rolf E. Swenson, Charles J. Nichols, Nicholas A. Mort, Jonathan Greer
  • LHRH antagonists having lactam groups at the N-terminus
    Patent number: 5516759
    Abstract: Peptides possessing LHRH antagonistic activity, and useful for the controlling the release of LHRH in mammals are decapeptide analogues of LHRH having a lactam group at the N-terminus of the formula ##STR1## where n is 1, 2, or 3 and R.sup.1 is selected from the group consisting of hydrogen, benzyl, 4-chlorobenzyl, 2-methylnaphth-1-yl, 1-methylnaphth-2-yl, and quinolin-3-ylmethyl.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: May 14, 1996
    Assignee: TAP Holdings Inc.
    Inventors: Rolf E. Swenson, Fortuna Haviv, Nicholas A. Mort
  • N-terminus modified analogs of LHRH
    Patent number: 5502035
    Abstract: Decapaptide and undecapaptides substituted on the N-terminal nitrogen atom by acyl groups which include furo-2-yl, isonicotinyl, nicotinyl, 2-, 3-, and 4-quinolinecarbonyl, shikimyl, dihydroshikimyl, and tetrahydrofur-2-oyl are potent antagonists of LHRH and are useful for suppressing the levels of sex hormones in mammals.
    Type: Grant
    Filed: July 27, 1994
    Date of Patent: March 26, 1996
    Assignee: Tap Holdings Inc.
    Inventors: Fortuna Haviv, Timothy D. Fitzpatrick, Rolf E. Swenson, Charles J. Nichols, Nicholas A. Mort
  • N-terminus modified analogs of LHRH
    Patent number: 5413990
    Abstract: Decapaptides substituted on the N-terminal nitrogen atom by acyl groups are potent antagonists of LHRH and are useful for suppressing the levels of sex hormones in mammals.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: May 9, 1995
    Assignee: Tap Pharmaceuticals Inc.
    Inventors: Fortuna Haviv, Timothy D. Fitzpatrick, Rolf E. Swenson, Charles J. Nichols, Nicholas A. Mort