Patents by Inventor Nicholas Morrell

Nicholas Morrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellular substrate for nuclear reprogramming
    Patent number: 9963681
    Abstract: This invention relates to the use of late out-growth endothelial progenitor cells (L-EPCs) as a cellular substrate for the generation of Induced pluripotent stem cells (iPSCs). This may be useful in the production of patient-specific tissues for disease modelling, drug and toxicology screening, tissue replacement and delivery of gene therapy.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: May 8, 2018
    Assignee: Cambridge Enterprise Limited
    Inventors: Nicholas Morrell, Mark Ormiston, Amer Rana, Ludovic Vallier
  • Methods of modulating MicroRNAs in the treatment of pulmonary arterial hypertension
    Patent number: 9267134
    Abstract: The present invention provides a method of treating or preventing pulmonary arterial hypertension in a subject in need thereof by administering to the subject an inhibitor of miR-145 expression or activity. Pharmaceutical compositions and kits comprising miR-145 inhibitors for treating pulmonary arterial hypertension are also disclosed.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: February 23, 2016
    Assignees: The University Court of the University of Glasgow, Cambridge Enterprise Limited
    Inventors: Andrew Baker, Margaret MacLean, Nicholas Morrell
  • Cannon breechblock insert assembly
    Patent number: 8857308
    Abstract: A sliding breechblock for a cannon includes a translatable, removable insert assembly that contains electrical firing pin and data link modules. The removable insert assembly is translatable in a direction normal to the central longitudinal axis of the barrel thereby enabling removal of the insert assembly without removing the breechblock from the breech ring. Mating portions formed on the breechblock and on the insert assembly prevent displacement of the insert assembly with respect to the breechblock in the direction along the central longitudinal axis of the barrel.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: October 14, 2014
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Joseph Kurowsky, Nicholas Morrell, III, Alan Ng, Adam Blot
  • Methods of Modulating MicroRNAs in the Treatment of Pulmonary Arterial Hypertension
    Publication number: 20140163086
    Abstract: The present invention provides a method of treating or preventing pulmonary arterial hypertension in a subject in need thereof by administering to the subject an inhibitor of miR-145 expression or activity. Pharmaceutical compositions and kits comprising miR-145 inhibitors for treating pulmonary arterial hypertension are also disclosed.
    Type: Application
    Filed: May 9, 2012
    Publication date: June 12, 2014
    Applicants: CAMBRIDGE ENTERPRISE LIMITED, THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
    Inventors: Andrew Baker, Margaret MacLean, Nicholas Morrell
  • Cellular Substrate for Nuclear Reprogramming
    Publication number: 20140093963
    Abstract: This invention relates to the use of late out-growth endothelial progenitor cells (L-EPCs) as a cellular substrate for the generation of Induced pluripotent stem cells (iPSCs). This may be useful in the production of patient-specific tissues for disease modelling, drug and toxicology screening, tissue replacement and delivery of gene therapy.
    Type: Application
    Filed: March 30, 2012
    Publication date: April 3, 2014
    Applicant: Cambridge Enterprise Limited
    Inventors: Nicholas Morrell, Mark Ormiston, Amer Rana, Ludovic Vallier
  • Bracket system adapted for use in a raising and lowering mechanism of an adjustable headrest of a vehicle seat
    Patent number: 8162401
    Abstract: The present invention relates to a bracket system (1) adapted for use in a raising and lowering mechanism of an adjustable headrest (4) of a vehicle seat. The inventive bracket system (1) adapted for use in a raising and lowering mechanism of an adjustable headrest (4) of a vehicle seat comprises a spring element (8) an actuation arm (7) a longitudinal carrier bar (2) carrying the head rest (4) and having on its surface at least one notch of a first kind (9) and at least one notch of a second kind (10).
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: April 24, 2012
    Assignees: Kongberg Automotive AB, Johnson Controls GmbH
    Inventors: Arnout Homan, Nicholas Morrell, Anders Kvarnstrom
  • BRACKET SYSTEM ADAPTED FOR USE IN A RAISING AND LOWERING MECHANISM OF AN ADJUSTABLE HEADREST OF A VEHICLE SEAT
    Publication number: 20100171354
    Abstract: The present invention relates to a bracket system (1) adapted for use in a raising and lowering mechanism of an adjustable headrest (4) of a vehicle seat. The inventive bracket system (1) adapted for use in a raising and lowering mechanism of an adjustable headrest (4) of a vehicle seat comprises a spring element (8) an actuation arm (7) a longitudinal carrier bar (2) carrying the head rest (4) and having on its surface at least one notch of a first kind (9) and at least one notch of a second kind (10).
    Type: Application
    Filed: May 7, 2007
    Publication date: July 8, 2010
    Inventors: Arnout Homan, Nicholas Morrell, Anders Kvarnstrom