Patents by Inventor Nicholas S. Bodor

Nicholas S. Bodor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of dosing and use of soft anticholinergic esters
    Patent number: 9492429
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: November 15, 2016
    Assignee: BODOR LABORATORIES, INC.
    Inventors: Nicholas S. Bodor, David Angulo
  • METHOD OF DOSING AND USE OF SOFT ANTICHOLINERGIC ESTERS
    Publication number: 20160310464
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Application
    Filed: July 1, 2016
    Publication date: October 27, 2016
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO
  • METHOD OF DOSING AND USE OF SOFT ANTICHOLINERGIC ESTERS
    Publication number: 20160067214
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Application
    Filed: November 13, 2015
    Publication date: March 10, 2016
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO
  • USE OF SELECTED ANTICHOLINERGIC ZWITTERIONS
    Publication number: 20150374621
    Abstract: Selected anticholinergic zwitterions are administered to slow the progression of myopia in children and to treat myopia generally.
    Type: Application
    Filed: September 4, 2015
    Publication date: December 31, 2015
    Inventor: Nicholas S. BODOR
  • Method of dosing and use of soft anticholinergic esters
    Patent number: 9220707
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 29, 2015
    Assignee: BODOR LABORATORIES, INC.
    Inventors: Nicholas S. Bodor, David Angulo
  • FORMULATION FOR SOFT ANTICHOLINERGIC ANALOGS
    Publication number: 20150320722
    Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: Nicholas S. BODOR, John J. Koleng, David Angulo
  • METHOD OF DOSING AND USE OF SOFT ANTICHOLINERGIC ESTERS
    Publication number: 20140275204
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: BODOR LABORATORIES, INC.
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO
  • Treatment of eyelid dermatitis
    Patent number: 8835410
    Abstract: A method for the treatment of eyelid dermatitis and/or dermatitis of the periorbital area is provided.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: September 16, 2014
    Assignee: Bodor Laboratories, Inc.
    Inventor: Nicholas S. Bodor
  • Oral formulations of cladribine
    Patent number: 8785415
    Abstract: Provided are compositions of cladribine and cyclodextrin which are especially suited for the oral administration of cladribine.
    Type: Grant
    Filed: January 7, 2011
    Date of Patent: July 22, 2014
    Assignee: Ares Trading S.A.
    Inventors: Nicholas S. Bodor, Yogesh Dandiker
  • Soft anticholinergic esters
    Patent number: 8628759
    Abstract: Soft anticholinergic esters of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; R is C1-C8 alkyl, straight or branched chain; and X? is an anion with a single negative charge; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: January 14, 2014
    Assignee: Bodor Laboratories, Inc.
    Inventor: Nicholas S. Bodor
  • Cladribine formulations for improved oral and transmucosal delivery
    Patent number: 8623408
    Abstract: Provided are compositions of cladribine and cyclodextrin which are especially suited for the oral and buccal administration of cladribine.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: January 7, 2014
    Assignee: Ares Trading S.A.
    Inventor: Nicholas S Bodor
  • Soft anticholinergic zwitterions
    Patent number: 8568699
    Abstract: Soft anticholinergic zwitterions of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: October 29, 2013
    Inventor: Nicholas S. Bodor
  • TREATMENT OF EYELID DERMATITIS
    Publication number: 20120289486
    Abstract: A method for the treatment of eyelid dermatitis and/or dermatitis of the periorbital area is provided.
    Type: Application
    Filed: May 10, 2011
    Publication date: November 15, 2012
    Inventor: Nicholas S. BODOR
  • SOFT ANTICHOLINERGIC ESTERS
    Publication number: 20120177590
    Abstract: Soft anticholinergic esters of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; R is C1-C8 alkyl, straight or branched chain; and X? is an anion with a single negative charge; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.
    Type: Application
    Filed: March 16, 2012
    Publication date: July 12, 2012
    Inventor: Nicholas S. BODOR
  • SOFT ANTICHOLINERGIC ZWITTERIONS
    Publication number: 20120141401
    Abstract: Soft anticholinergic zwitterions of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.
    Type: Application
    Filed: October 31, 2011
    Publication date: June 7, 2012
    Inventor: Nicholas S. Bodor
  • Soft anticholinergic esters
    Patent number: 8147809
    Abstract: Soft anticholinergic esters of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; R is C1-C8 alkyl, straight or branched chain; and X? is an anion with a single negative charge; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: April 3, 2012
    Inventor: Nicholas S. Bodor
  • Soft anticholinergic zwitterions
    Patent number: 8071639
    Abstract: Soft anticholinergic zwitterions of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: December 6, 2011
    Inventor: Nicholas S. Bodor
  • ORAL FORMULATIONS OF CLADRIBINE
    Publication number: 20110097306
    Abstract: Provided are compositions of cladribine and cyclodextrin which are especially suited for the oral administration of cladribine.
    Type: Application
    Filed: January 7, 2011
    Publication date: April 28, 2011
    Applicant: ARES TRADING S.A.
    Inventors: Nicholas S. Bodor, Yogesh Dandiker
  • Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application
    Patent number: 7923441
    Abstract: Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17?-alkoxycarbonyloxy-11?-hydroxyandrost-4-en-3-one-17?-carboxylate type and the corresponding ?1,4-compounds are described. The enhancing agents have the formula: wherein R is H or C1-C4 alkyl; Z1 is carbonyl or ?-hydroxymethylene; X1 is —O— or —S—; R5 is —OH, —OR6, —OCOOR6 or —OCOR7 wherein R6 is C1-C4 alkyl and R7 is C1-C4 alkyl, fluoromethyl or chloromethyl; and the dotted line in ring A indicates that the 1,2-linkage is saturated or unsaturated; with the proviso that when R is C1-C4 alkyl, then R5 is —OH.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: April 12, 2011
    Inventor: Nicholas S. Bodor
  • Oral formulations of cladribine
    Patent number: 7888328
    Abstract: Provided are compositions of cladribine and cyclodextrin which are especially suited for the oral administration of cladribine.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: February 15, 2011
    Assignee: Ares Trading S.A.
    Inventors: Nicholas S. Bodor, Yogesh Dandiker