Patents by Inventor Nicolaas Martha Felix Goyvaerts

Nicolaas Martha Felix Goyvaerts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING ATICAPRANT
    Publication number: 20230277500
    Abstract: The present disclosure relates to compositions, including oral compositions in the form of tablets, comprising aticaprant and methods of using the same.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 7, 2023
    Inventors: Nicolaas Martha Felix Goyvaerts, Mark Schmidt, Vanina Popova, Adam Savitz, Rama Melkote, Wayne C. Drevets, Srihari Gopal, Darrel Pemberton, Chakradhar Lagishetty, Iva Kezic, Mahesh N. Samtani, Tom Huybrechts, Geert Van der Avoort, Matthieu Ravelingien, Laura Martinez Marcos, Tatiana Marcozzi, Katarina Jokicevic
  • DISPERSIBLE COMPOSITIONS
    Publication number: 20220008333
    Abstract: The present invention is concerned with dispersible compositions comprising rilpivirine or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. Such compositions are useful in the treatment of HIV infection and their dispersibility properties lend themselves to be useful in particular amongst the pediatric or geriatric population.
    Type: Application
    Filed: June 15, 2021
    Publication date: January 13, 2022
    Inventors: Harshad Patankar, Nicolaas Martha Felix Goyvaerts, Gopal Rajan Ranga Rajan
  • Dispersible compositions
    Patent number: 11065198
    Abstract: The present invention is concerned with dispersible compositions comprising rilpivirine or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. Such compositions are useful in the treatment of HIV infection and their dispersibility properties lend themselves to be useful in particular amongst the pediatric or geriatric population.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: July 20, 2021
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Harshad Patankar, Nicolaas Martha Felix Goyvaerts, Gopal Rajan Ranga Rajan
  • DISPERSIBLE COMPOSITIONS
    Publication number: 20200069579
    Abstract: The present invention is concerned with dispersible compositions comprising rilpivirine or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. Such compositions are useful in the treatment of HIV infection and their dispersibility properties lend themselves to be useful in particular amongst the pediatric or geriatric population.
    Type: Application
    Filed: October 23, 2017
    Publication date: March 5, 2020
    Inventors: Harshad Patankar, Nicolaas Martha Felix Goyvaerts, Gopal Rajan Ranga Rajan
  • Process for the preparation of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate
    Patent number: 7772411
    Abstract: The present invention relates to a process for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate as well as intermediates for use in said process. More in particular the invention relates to processes for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate which make use of 4-amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl)benzene sulfonamide intermediate, and to processes amenable to industrial scaling up. (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as HIV protease inhibitors.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: August 10, 2010
    Assignee: Tibotec Pharmaceuticals Ltd.
    Inventors: Nicolaas Martha Felix Goyvaerts, Piet Tom Bert Paul Wigerinck, Hartmut Burghard Zinser, Birgit M. Ebert
  • Process for the preparation of (3r,3as,6ar)-hexahydrofuro [2,3-b] furan-3-yl (1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate
    Publication number: 20070060642
    Abstract: The present invention relates to a process for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate as well as intermediates for use in said process. More in particular the invention relates to processes for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate which make use of 4-amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl)benzene sulfonamide intermediate, and to processes amenable to industrial scaling up. (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as HIV protease inhibitors.
    Type: Application
    Filed: December 23, 2004
    Publication date: March 15, 2007
    Inventors: Nicolaas Martha Felix Goyvaerts, Piet Wigerinck, Hartmut Zinser, Birgit Ebert