Patents by Inventor Nicolae Ghinea

Nicolae Ghinea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies against the human fshr extracellular domain
    Patent number: 11851496
    Abstract: The invention relates to anti-human follicle-stimulating hormone receptor antibodies. The invention also relates to use of the anti-human follicle-stimulating hormone receptor antibodies in the treatment of cancer. The present invention also relates to a process for detecting cancerous cells and a process for diagnosis cancer. The present invention finds an application in the therapeutic and diagnostic medical technical fields.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: December 26, 2023
    Assignee: FSHR THERANOSTICS SAS
    Inventor: Nicolae Ghinea
  • ANTIBODIES AGAINST THE HUMAN FSHR EXTRACELLULAR DOMAIN
    Publication number: 20210130481
    Abstract: The invention relates to anti-human follicle-stimulating hormone receptor antibodies. The invention also relates to use of the anti-human follicle-stimulating hormone receptor antibodies in the treatment of cancer. The present invention also relates to a process for detecting cancerous cells and a process for diagnosis cancer. The present invention finds an application in the therapeutic and diagnostic medical technical fields.
    Type: Application
    Filed: December 9, 2020
    Publication date: May 6, 2021
    Inventor: NICOLAE GHINEA
  • Human follicle-stimulating hormone receptor (FSHR) extracellular domain antibodies and methods of use thereof
    Patent number: 10927179
    Abstract: The invention relates to anti-human follicle-stimulating hormone receptor antibodies. The invention also relates to use of the anti-human follicle-stimulating hormone receptor antibodies in the treatment of cancer. The present invention also relates to a process for detecting cancerous cells and a process for diagnosis cancer. The present invention finds an application in the therapeutic and diagnostic medical technical fields.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: February 23, 2021
    Assignees: INSERM—INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, INSTITUT CURIE
    Inventor: Nicolae Ghinea
  • ANTIBODIES AGAINST THE HUMAN FSHR EXTRACELLULAR DOMAIN
    Publication number: 20200010556
    Abstract: The invention relates to anti-human follicle-stimulating hormone receptor antibodies. The invention also relates to use of the anti-human follicle-stimulating hormone receptor antibodies in the treatment of cancer. The present invention also relates to a process for detecting cancerous cells and a process for diagnosis cancer. The present invention finds an application in the therapeutic and diagnostic medical technical fields.
    Type: Application
    Filed: March 7, 2018
    Publication date: January 9, 2020
    Inventor: NICOLAE GHINEA
  • Use of FSH receptor ligands for diagnosis and therapy of cancer
    Patent number: 9200076
    Abstract: The present invention relates to diagnostic imaging and in particular to the diagnostic imaging and therapy of cancer by means of compositions which specifically target the FSH Receptor expressed by tumor endothelial cells and circulating blood cells.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: December 1, 2015
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Nicolae Ghinea, Aurelian Radu
  • USE OF FSH RECEPTOR LIGANDS FOR DIAGNOSIS AND THERAPY OF CANCER
    Publication number: 20140328758
    Abstract: The present invention relates to diagnostic imaging and in particular to the diagnostic imaging and therapy of cancer by means of compositions which specifically target the FSH Receptor expressed by tumor endothelial cells and circulating blood cells.
    Type: Application
    Filed: July 17, 2014
    Publication date: November 6, 2014
    Inventors: NICOLAE GHINEA, AURELIAN RADU
  • Use of FSH receptor ligands for diagnosis and therapy of cancer
    Patent number: 8784776
    Abstract: The present invention relates to diagnostic imaging and in particular to the diagnostic imaging and therapy of cancer by means of compositions which specifically target the FSH Receptor expressed by tumor endothelial cells and circulating blood cells.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: July 22, 2014
    Assignees: Inserm (Institut National de la Sante et de la Recherche Medicale), Mount Sinai School of Medicine
    Inventors: Nicolae Ghinea, Aurelian Radu
  • NOVEL METHODS FOR PREDICTING THE RESPONSIVENESS OF A PATIENT AFFECTED WITH A TUMOR TO A TREATMENT WITH A TYROSINE KINASE INHIBITOR
    Publication number: 20130131136
    Abstract: The present invention relates to a method for predicting the responsiveness of a patient affected with a tumor to a treatment with a tyrosine kinase inhibitor such as sunitinib. More specifically, the method of the invention comprises a step of determining the expression level of one marker consisting of the FSHR in a biological sample obtained from said patient, and more specifically in the blood endothelial cells from the tumors.
    Type: Application
    Filed: August 1, 2011
    Publication date: May 23, 2013
    Inventors: Nicolae Ghinea, Aurelian Radu
  • USE OF FSH RECEPTOR LIGANDS FOR DIAGNOSIS AND THERAPY OF CANCER
    Publication number: 20100316572
    Abstract: The present invention relates to diagnostic imaging and in particular to the diagnostic imaging and therapy of cancer by means of compositions which specifically target the FSH Receptor expressed by tumor endothelial cells and circulating blood cells.
    Type: Application
    Filed: February 18, 2009
    Publication date: December 16, 2010
    Applicants: Institut National De La Sante Et De La Recherche Medicale (Inserm), Mount Sinai School of Medicine
    Inventors: Nicolae Ghinea, Aurelian Radu