Abstract: The present document relates to amphiphilic poly(monoglycerol acrylate) (PMGA) polymers, comprising an hydrophilic repeating unit of monoglycerol acrylate and one or more biodegradable hydrophobic group and their use and methods of use in the delivery of bioactive agents. Additionally, the invention provides a method for preparing monoglycerol acrylate-based polymers.

Abstract: The invention is based on the discovery of a new bacterial compound with analgesic properties which could be used as a new tool for the treatment of pain disorders such as visceral pain. Studying the mechanisms implicated in analgesic properties of the probiotic Escherichia coli strain Nissle 1917 (EcN), inventors characterized, the amino fatty acids produced by EcN, which display the Ecn analgesic properties. One of these compounds inhibits the hypersensitivity to colorectal distension induced by capsaicin, which is a very powerful nociceptive compound and acts via the GABA B receptor. Furthermore, inventors demonstrate that this compound is able to cross the cellular epithelial barrier (such as the intestinal epithelium). Thus, the invention relates to a lipopetide compound, derived from gamma-aminobutyric acid. The invention also relates to a lipopeptide compound according to the invention for the treatment of treating pain disorder, such as somatic pain and visceral pain.

Abstract: An actuation system includes: a generating rotating electrical machine including a first stator including at least one output stator winding; a driving rotating electrical machine including a second rotor, intended to actuate a lubrication pump, and a second stator including at least one input stator winding; an array of switches electrically connected to the at least one output stator winding and to the at least one input stator winding, for electrically connecting them together or disconnecting them from each other depending on the state of the array of switches; and a control device configured to control the array of switches, depending on the state of a control signal, in such a way as to electrically connect or not connect the at least one output stator winding and the at least one input stator winding together.

Abstract: In an electromechanical actuation chain for controlling the movement of mobile loads of an aircraft turbine engine, from a control unit, one or more of these mobile loads being actuated by an electromechanical actuator, there is provided for control of this movement a single Ethernet controller having deterministic control that uses an Ethernet bus to control a set of converters acting selectively on the electromechanical actuators.

Abstract: The invention relates to a sprayer, comprising an air guiding element and means for fastening the air guiding element on a fixed member of the sprayer. The fastening means comprise at least one magnetic attraction means mounted on a first component from among the air guiding element and the fixed member and at least one part made from a ferromagnetic material, which is intended to cooperate with the magnetic attraction means and which is mounted on or formed by the other component from among the air guiding element and the fixed element.

Abstract: A power distribution device between an electric starter of a turbomachine and an electric machine toward a shaft of the turbomachine, including the electric starter, the electric machine, and a controller for controlling the electric machine. An epicyclic train reducer includes a first element intended to be coupled to the shaft, a second element coupled to the electric starter, and a third element intended to be rotated by the electric machine. The controller is configured to rotate the third of the three elements so as to obtain two bearings of reduction ratios of the speeds between the first of said three elements and the second of the three elements. The controller is configured to drive the torque of the third of the three elements in accordance with a determined output torque.

Abstract: The invention concerns a bypass turbomachine (1) with a primary flow path and a secondary flow path, comprising: —a low-pressure body comprising a low-pressure compressor (120) connected to a low-pressure turbine (122) via a low-pressure shaft (124), —a high-pressure body comprising a high-pressure compressor (130) connected to a high pressure turbine (132), via a high-pressure shaft (134), —a low-pressure power take-off system (220) comprising an electrical generator (226), configured to take power (W12) from the low-pressure body, wherein—the turbomachine comprises a debris removal system (500), located between the two compressors (226, 236), —the low-pressure power take-off system (220) is configured to take power (W12) from the low-pressure shaft (124) using the resistive torque of the electrical generator (226), in order to avoid a risk of surging.

Abstract: A power distribution device between an electric starter of a turbomachine and an electric machine toward a shaft of the turbomachine, including the electric starter, the electric machine, and a controller for controlling the electric machine. An epicyclic train reducer includes a first element intended to be coupled to the shaft, a second element coupled to the electric starter, and a third element intended to be rotated by the electric machine. The controller is configured to rotate the third of the three elements so as to obtain two bearings of reduction ratios of the speeds between the first of said three elements and the second of the three elements. The controller is configured to drive the torque of the third of the three elements in accordance with a determined output torque.

Abstract: The invention relates to a sprayer, comprising an air guiding element and means for fastening the air guiding element on a fixed member of the sprayer. The fastening means comprise at least one magnetic attraction means mounted on a first component from among the air guiding element and the fixed member and at least one part made from a ferromagnetic material, which is intended to cooperate with the magnetic attraction means and which is mounted on or formed by the other component from among the air guiding element and the fixed element.

Abstract: The present invention provides a novel method for diagnosing, monitoring, prognosing and staging Lymph Node (LN) status in colorectal cancer (CRC) that is more sensitive and accurate than conventional detection technologies such as histopathology. The Guanylyl Cyclase C (GCC) gene is specifically expressed in apical epithelial cells of the GI tract from the duodenum to the rectum and the detection of GCC mRNA in LNs is indicative of the presence of metastases. Quantitative RT-PCR (RT-qPCR) detection of GCC mRNA to identify the presence of colorectal cancer (CRC) cells in LNs has the potential to aid in CRC staging. When used in combination with glucuronidase B (GUSB), accurate quantification of GCC can be achieved with less than a 2-fold variation between intact and highly degraded RNA specimens.

Abstract: In this method for the surface treatment of a metal part (12) for the purpose of deoxidizing it and/or cleaning it, a sealed chamber (16), in which the part to be treated is placed, is filled with a low-pressure reducing gas mixture, a static magnetic field is created in a region of the chamber (16) separate from the region in which the part (12) to be treated is placed and the gas mixture is excited by means of an electromagnetic wave injected into the chamber (16) so as to generate a treatment plasma in the gas, the intensity of the static magnetic field corresponding to electron cyclotron resonance established in the chamber in a distributed manner.