Abstract: The disclosure concerns a method of replacing a current key in a security element co-operating with a terminal in a network operated by a network operator, the method includes trying to decrypt the encrypted message by using the current key; selecting in a table stored in the secure element another key and try to decrypt the encrypted message by using the other key; replacing atomically the current key by the rescue key and do not use the current key anymore, the rescue key replacing the current key and, otherwise, try to decrypt the encrypted message by using another rescue key of the window if such another rescue key exists, until all rescue keys have been selected and used for decrypting the encrypted message and, if none of the rescue keys permit to decrypt the encrypted message, select the blocking key; and blocking the corresponding functionality of the security element.

Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.

Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.

Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.

Abstract: An optoelectronic circuit for receiving a variable voltage containing alternating increasing and decreasing phases. The optoelectronic circuit includes assemblies of light-emitting diodes mounted in series; a current source connected to each assembly by a switch; for each switch, a first comparison module for comparing the current passing through the switch with a current threshold; a second comparison module for comparing a voltage representing the voltage at the terminals of the current source with a voltage threshold; and a control module connected to the first and second comparison modules and designed to control the opening and closing of the switches, during each increasing phase and each decreasing phase, according to signals supplied by the first and second comparison modules.

Abstract: An optoelectronic circuit for receiving a variable voltage containing alternating increasing and decreasing phases. The optoelectronic circuit includes assemblies of light-emitting diodes mounted in series; a current source connected to each assembly by a switch; for each switch, a first comparison module for comparing the current passing through the switch with a current threshold; a second comparison module for comparing a voltage representing the voltage at the terminals of the current source with a voltage threshold; and a control module connected to the first and second comparison modules and designed to control the opening and closing of the switches, during each increasing phase and each decreasing phase, according to signals supplied by the first and second comparison modules.

Abstract: A first device stores a subscription manager and at least two subscriptions. A first subscription is active and a second subscription is non-active. A second device sends a request for switching to the second subscription. The subscription manager sets a first variable relating to a next active subscription to the second subscription. The subscription manager sends to the first device a message requesting the first device to re-launch an execution of the subscription manager and to read data. The first device sends to the subscription manager a message including a command for re-launching an execution of the subscription manager. The subscription manager de-activates, based upon the first variable value, the first subscription. The subscription manager activates, based upon the first variable value, the second subscription, and sends to the first device operating system data relating to the second subscription, as a current active subscription.

Abstract: A first device stores a subscription manager and at least two subscriptions. A first subscription is active and a second subscription is non-active. A second device sends a request for switching to the second subscription. The subscription manager sets a first variable relating to a next active subscription to the second subscription. The subscription manager sends to the first device a message requesting the first device to re-launch an execution of the subscription manager and to read data. The first device sends to the subscription manager a message including a command for re-launching an execution of the subscription manager. The subscription manager de-activates, based upon the first variable value, the first subscription. The subscription manager activates, based upon the first variable value, the second subscription, and sends to the first device operating system data relating to the second subscription, as a current active subscription.

Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.

Abstract: The invention relates to a UICC comprising a toolkit applet. The UICC comprises a toolkit security component for establishing and using a secure channel for proactive commands and events exchanged by the toolkit applet of the UICC with a mobile equipment. Other communications between the UICC and the mobile equipment take place outside of this secure channel. The invention also relates to a system comprising a UICC of the above type and a mobile equipment, such as a cell phone. The invention also relates to a method to selectively protect a UICC.

Abstract: (EN)The invention relates to a UICC comprising a toolkit applet. The UICC comprises a toolkit security component for establishing and using a secure channel for proactive commands and events exchanged by the toolkit applet of the UICC with a mobile equipment. Other communications between the UICC and the mobile equipment take place outside of this secure channel. The invention also relates to a system comprising a UICC of the above type and a mobile equipment, such as a cell phone. The invention also relates to a method to selectively protect a UICC.

Abstract: The invention relates to the use of an uridine derivative of formula (I); wherein —R1 represents monohalogenated alkynyl or dihalogenated alkenyl; —R2 is chosen from among hydrogen, hydroxyl, O-alkyl, O—CO alkyl and halogen; —R3 is chosen from among hydrogen, hydroxyl, O-alkyl, O—CO alkyl, halogen, SH, S-alkyl and N3; and —R4 is chosen from among hydroxyl, O-alkyl, O—CO alkyl, O-phosphate, O-diphosphate, O-triphosphate and O phosphonate, as well as its possible tautomers, its possible pharmaceutically acceptable addition salts with an acid or a base, and its N-oxide forms, for the preparation of a drug having antiviral activity against a Flaviviridae.