Abstract: A composition, containing 10 to 70% of indocyanine green, 0.1 to 15% of ethylenediaminetetraacetic acid (EDTA) and/or one or more salts thereof, 1 to 20% of histidine, and 20 to 80% of sodium chloride. The percentages are expressed by weight relative to a total weight of the indocyanine green, EDTA, histidine, and sodium chloride.

Abstract: A composition, containing indocyanine green (a), and histidine (b). A weight ratio of histidine (b)/indocyanine green (a) is greater than 0.05. A kit for preparing the composition, containing in separate compartments the indocyanine green (a), and an aqueous solution including the histidine (b). The composition is a medicament or a diagnostic agent.

Abstract: A cryptographic processing method comprises the following steps: obtaining a second number determined by adding to a first number the order of a finite group or a multiple of this order; determining a quotient and a remainder by dividing the second number by a random number; obtaining a third element equal to the combination of elements equal to a first element of the finite group and in number equal to the product of the quotient and the random number; obtaining a fourth element equal to the combination of elements equal to the first element and in number equal to the remainder; determining a second element by combining the third element and the fourth element.

Abstract: A ceramic for construction or technical applications, composed of at least one of Municipal Solid Waste Incinerator Bottom Ash (MSWIBA) and other recycled industrial solid waste and different methods of forming such ceramics. Various techniques illustrate how ceramics are formed using at least one of extrusion shaping, dry powder compaction and agglomeration, any of which can be preceded by a pre-treatment process of received feedstock.

Abstract: An adaptive lighting system comprises an array of independently controllable LEDs, and a metalens positioned to collimate, focus, or otherwise redirect light emitted by the array of LEDs. The adaptive lighting system may optionally include a pre-collimator positioned in the optical path between the array of LEDs and the metalens.

Abstract: A process for synthesizing a compound of formula (I) including: (a) condensing the benzaldehyde compound of formula (II) with the dialkylaniline of formula (III) to give the triphenylmethane of formula (IV); (b) treating the triphenylmethane of formula (IV) with sulfuric acid to form the triphenylmethane sulfone of the formula (V); and (c) oxidizing the triphenylmethane sulfone of formula (V) with a quinone. Such a process may be used to prepare patent blue.

Abstract: A device that is able to generate a segmentation mask for an object in a digital image is provided. To do so, the device comprises a processing logic that is configured to use a previously trained auto-encoder to encode the image, and decode the image generating an additional alpha channel, which defines the segmentation mask.

Abstract: A device for reducing crosstalk in an audio system that has first and second pairs of loudspeakers and first and second audio sources. The device is connected to each audio source and to at least the first pair of loudspeakers. The device includes a module for acquiring first audio signals from the first source and second audio signals from the second source, a module for determining crosstalk reduction filters resulting from a loudspeaker of the second pair, a module for calculating corrective signals, by applying the reduction filters to the second audio signals, and a module for generating corrected audio signals for the first pair, obtained from the first audio signals and corrective signals. Each reduction filter is obtained from transfer functions, each representing an acoustic path between a loudspeaker and a user's ear.

Abstract: A method and a system for improving the low-frequency sound reproduction of an audio signal, the sound reproduction being performed by an audio system comprising at least one loudspeaker. The system includes a low-frequency sound enhancement module with filters for separating an input audio signal into a high-frequency signal and a low-frequency signal. The system is configured to implement a first audio processing of the low-frequency signal to obtain a low-frequency output signal and a second audio processing of the high-frequency signal to obtain a high-frequency output signal. The low-frequency sound enhancement module includes, for the first processing of the low-frequency signal, a module for increasing the dynamic range of the low-frequency signal, which is parameterised as a function of at least one transient part of the low-frequency signal.

Abstract: An audio processing method and system for a seat headrest audio system, the audio system including at least two speakers positioned on opposite sides of the headrest, the method including detecting a position of the user's head and adjusting a first set of parameters of at least one audio processing operation as a function of that position. The method includes determining a user characteristic and/or temporary state of the user, selecting an audio settings profile related to that characteristic, the audio settings profile including a second set of prerecorded audio profile parameters, and adjusting a third set of audio parameters effectively applied to control the audio rendering of each speaker, based on the first and second sets of parameters.

Abstract: A gravel pack containing a substrate particle coated with an inducibly degradable and a porous particle having an internal interconnected porosity that is at least partially infused with an inducer material for dissolving of a layer of filter cake disposed between the gravel pack and a subterranean formation.

Abstract: A process for preparing a compound of formula including oxidizing the triphenylmethane sulfone of formula (V) with a quinone chosen from 1,4-benzoquinone, 1,2-benzoquinone, a di(C1-C4)alkyl-1,4-benzoquinone, a di(C1-C4)alkyl-1,2-benzoquinone, a mono(C1-C4)alkyl-1,4-benzoquinone and a mono(C1-C4)alkyl-1,2-benzoquinone. A crystalline form of patent blue, sodium salt, can be achieved.

Abstract: A gravel pack containing a substrate particle coated with an inducibly degradable and a porous particle having an internal interconnected porosity that is at least partially infused with an inducer material for dissolving of a layer of filter cake disposed between the gravel pack and a subterranean formation.

Abstract: Endometriosis is a chronic inflammatory systemic sex hormone-dependent gynecological disease, characterized by the presence and growth of endometrial tissue (glands and stroma) outside the uterine cavity, predominantly, but not exclusively, in the pelvic compartment. Here, the inventors show that the use of Neuropilin/VEGF binding inhibitors, so called, Neuropilin antagonist (NRPa), bring new perspective to treat and cure endometriosis in women suffering thereof. NRPa alone is efficient to inhibit primary endometrial cell proliferation and apoptosis/necrosis program cell death of targeted cells. The effective NRPa concentration needed is very low (NRPa-48 IC50=10?7M) and is dependent of the NRPa structure. Moreover, the association of NRPa with progestogen drug increases the anti-proliferative effect. Therefore, the present invention relates to the use of neuropilin antagonists for the treatment of endometriosis.

Abstract: A computer-implemented method for evaluating an amino acid chain is provided. The method includes obtaining first data including a representation of an amino acid chain and performing a process to generate second data comprising a set of one or more probability values. The representation comprises a sequence of two or more letters, each letter representing a respective amino acid. The second process comprises, for a said position in the sequence of letters, applying a language models to the sequence of letters to determine at least one probability value associated with the said position, wherein the language model is trained using one or more datasets representing amino acid chains. A computer system configured to implement the method, and a non-transitory computer-readable storage medium, storing instructions for implementing the method, is also provided.

Abstract: An audio system for a seat headrest includes N speaker(s), each configured to be integrated into a seat headrest, N being an integer greater than or equal to 1, and an audio processing device including an electronic transmission channel connected to the speaker(s) and configured to transmit at least one audio stream via the speaker(s). The audio system comprises P microphone(s), each configured to be integrated into the headrest, P being an integer greater than or equal to 1. The audio processing device further includes an electronic receiving channel connected to the microphone(s) and configured to receive at least one sound signal via the P microphone(s).

Abstract: Neuropilin-1 is henceforth a relevant target in cancer treatment, however way-of-action is remains partly elusive and the development of small inhibitory molecules is therefore required for its study. Here, the inventors report that two neuropilin small-sized antagonists (NRPa-47, NRPa-48), VEGF-A165/NRP-1 binding inhibitors, are able to decrease VEGF-Rs phosphorylation and to modulate their downstream cascades in triple negative breast cancer cell line (MDA-MB-231). In particular, the inventors showed for the first time, how NRPa may altered tumor cell signaling and contributed in the down-modulation of the cancer therapeutic key factor p38?-kinase phosphorylation. More importantly, the association of NRPa with a p38? inhibitor leads to additional and/or synergistic effect of these drugs (depending of the dose used) for significantly reducing breast cancer cell proliferation Thus, the efficient association of NRPa and p38?-kinase inhibitors are thus credible for the treatment of cancer.

Abstract: An audio processing method and system for a seat headrest audio system, the audio system including at least two speakers positioned on opposite sides of the headrest, the method including detecting a position of the user's head and adjusting a first set of parameters of at least one audio processing operation as a function of that position. The method includes determining a user characteristic and/or temporary state of the user, selecting an audio settings profile related to that characteristic, the audio settings profile including a second set of prerecorded audio profile parameters, and adjusting a third set of audio parameters effectively applied to control the audio rendering of each speaker, based on the first and second sets of parameters.

Abstract: A device for reducing crosstalk in an audio system that has first and second pairs of loudspeakers and first and second audio sources. The device is connected to each audio source and to at least the first pair of loudspeakers. The device includes a module for acquiring first audio signals from the first source and second audio signals from the second source, a module for determining crosstalk reduction filters resulting from a loudspeaker of the second pair, a module for calculating corrective signals, by applying the reduction filters to the second audio signals, and a module for generating corrected audio signals for the first pair, obtained from the first audio signals and corrective signals. Each reduction filter is obtained from transfer functions, each representing an acoustic path between a loudspeaker and a user's ear.

Abstract: An audio system for a headrest having a set of R right speaker(s), a set of L left speaker(s), and an electronic chain configured to emit a sound signal from at least a right input signal and a left input signal. The electronic chain includes a separating module configured to obtain, from the right input signal and the left input signal (LIN), at least four mono audio components, and a sound spatialization module configured to apply, to each mono audio component delivered by the separating module, a binaural filter previously selected from the plurality of binaural filters, and dedicated to the audio component, producing a sound whose source position is associated with the previously selected binaural filter.