Patents by Inventor Nicolas Sarrut

Nicolas Sarrut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060231398
    Abstract: A method of transferring mass of at least one solute between a liquid first phase and a fluid second phase that is immiscible with the first phase, the method comprising moving at least one droplet of said liquid first phase in a microfluidic device by using electric-type forces (electrowetting or dielectrophoresis) within a space that is filled with said fluid second phase. Said droplet is preferably moved by said electric-type forces along a path between a point for injecting said droplet into said microfluidic device, and an extraction and/or analysis zone, said path being defined in such a manner that said droplet sweeps through a significant fraction of said space filled with said fluid second phase. The method may include a step of transferring said droplet using said electric-type forces to a chemical analysis device integrated in said microfluidic device, and a step of chemically analyzing said droplet. The invention also provides a device for implementing such a method.
    Type: Application
    Filed: March 31, 2006
    Publication date: October 19, 2006
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Nicolas Sarrut, Hubert Jeanson
  • Patent number: 7094379
    Abstract: The invention relates to a microfluidic device for injecting series of mobile reaction chambers (102, 103) having non-miscible segmenters (101) in micro-channels (21 to 26), comprising: injection means (10) for injecting into microreaction channels alternatingly and in parallel liquid to form mobile reaction chambers and liquid for forming the segmenters; means for controlling the progression of one of the two liquids, applied to act on one zone (31) of each microchannel delimiting an injection volume of said liquid; the control means being able to cause stopping or slowing of the progression of said liquid over the zone of each microchannel by exerting an action based on a physico-chemical property of the liquid and said action not affecting the other liquid.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: August 22, 2006
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Yves Fouillet, Nicolas Sarrut, Antoine Gruss
  • Publication number: 20060042950
    Abstract: The microfluidic device comprises at least one microchannel bounded by a bottom wall, side walls and a top wall and which is designed to contain at least one liquid and at least one fluid non-miscible with the liquid. The microfluidic device comprises means for stabilizing the interface between the liquid and the fluid. The means for stabilizing comprise at least one electrode arranged on at least one part of a first wall of the microchannel, over the entire length thereof, and at least one counter-electrode arranged over the entire length of the microchannel, on at least one part of a second wall, arranged facing the electrode. The electrode and counter-electrode are preferably respectively arranged on the bottom and top wall of the microchannel.
    Type: Application
    Filed: November 27, 2003
    Publication date: March 2, 2006
    Applicant: Commissariat A L'Energie
    Inventor: Nicolas Sarrut
  • Publication number: 20050282224
    Abstract: Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.
    Type: Application
    Filed: August 4, 2005
    Publication date: December 22, 2005
    Applicants: Serono Genetics Institute S.A., Commissariat A L'Energie Atomique, a French government entity
    Inventors: Yves Fouillet, Claude Vauchier, Jean-Frederic Clerc, Christine Peponnet, Patricia Claustre, Raymond Charles, Nicolas Sarrut
  • Patent number: 6977145
    Abstract: Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: December 20, 2005
    Assignee: Serono Genetics Institute S.A.
    Inventors: Yves Fouillet, Claude Vauchier, Jean-Frederic Clerc, Christine Peponnet, Patricia Claustre, Raymond Charles, Nicolas Sarrut
  • Publication number: 20050196328
    Abstract: The invention relates to hydraulic device produced from one or several components, for example from a support comprising: an operative cavity, at least two ducts, for example an inlet and outlet for a liquid of interest which communicate with said operative cavity, at least two valve bodies with no moving pieces for control of said cavity. The above is characterised in that said device further comprises two trapping chambers for a gas, for example, air, in communication only and respectively with two ducts, by means of two connecting channels respectively, both pertaining to thermal exchange with a heat source.
    Type: Application
    Filed: June 24, 2003
    Publication date: September 8, 2005
    Applicants: Bio Merieux, Commissariat A L'Energie Atomique
    Inventors: Yves Fouillet, Patrick Pouteau, Nicolas Sarrut, Frederic Ginot, Dominique Masse
  • Publication number: 20040096359
    Abstract: The invention concerns a device (1) for the tight and reversible connection of at least one capillary (13) to a micro-fluidic component (2). The device comprises a rigid part (11) comprising means of positioning the capillary (13) so that it can be connected to the micro-fluidic component (2), means for attaching and positioning the rigid part with respect to the micro-fluidic component, a flexible seal (16) placed between the rigid part (11) and the micro-fluidic component (2) and through which the capillary (13) passes, the flexible seal (16) and the rigid part (11) making the tightness of the connection when the rigid part (11) is pressed by the attachment means onto the micro-fluidic component (2).
    Type: Application
    Filed: January 6, 2004
    Publication date: May 20, 2004
    Inventors: Nicolas Sarrut, Yves Fouillet, Raymond Charles, Jean-Antoine Gruss, Maurice Rostaing
  • Publication number: 20040053418
    Abstract: The invention concerns the performing, in continuous flow, of a biological, chemical or biochemical protocol on substances to be analysed, comprising several steps which consists in: in causing a mobile analysis support (11) comprising means (12) for receiving substances to be analysed and reagents to move past; implementing the steps of the protocol on the substances as the mobile analysis support (11) moves past.
    Type: Application
    Filed: July 21, 2003
    Publication date: March 18, 2004
    Inventors: Yves Fouillet, Raymond Charles, Nicolas Sarrut, Patricia Claustre
  • Publication number: 20040022686
    Abstract: The invention relates to a device (1) for distribution of at least one liquid product, the device comprising at least one injection tube (2) supplied by a liquid product and being provided with an outlet orifice (4) capable of cooperating with an inlet orifice (12) of a reception tube (10) for reception of each liquid product. According to the invention, the outlet orifice (4) of each injection tube (2) and the inlet orifice (12) of the reception tube (10) open up into a sealed reservoir (6) full of an immiscible liquid (8), the outlet orifice (4) of each injection tube (2) being at a spacing from the inlet orifice (12) of the reception tube (10) and able to be located close to the reception tube (12), the device (1) also comprising means (14) for pressurizing the immiscible liquid (8).
    Type: Application
    Filed: April 29, 2003
    Publication date: February 5, 2004
    Inventors: Raymond Charles, Yves Fouillet, Nicolas Sarrut, Patricia Claustre
  • Publication number: 20030082081
    Abstract: The invention relates to a microfluidic device for injecting series of mobile reaction chambers (102, 103) having non-miscible segmenters (101) in microchannels (21 to 26), comprising:
    Type: Application
    Filed: October 23, 2002
    Publication date: May 1, 2003
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Yves Fouillet, Nicolas Sarrut, Antoine Gruss
  • Publication number: 20010041357
    Abstract: Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.
    Type: Application
    Filed: January 29, 2001
    Publication date: November 15, 2001
    Inventors: Yves Fouillet, Claude Vauchier, Jean-Frederic Clerc, Christine Peponnet, Patricia Claustre, Raymond Charles, Nicolas Sarrut