Patents by Inventor Nicolas Smith
Nicolas Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230263555Abstract: Disclosed is a surgical assembly for reducing a fracture situated at bone epiphyses or joints including: an osteosynthesis support plate, a set of diaphyseal fixing members, a set of cannulated epiphyseal fixing members, a set of fixing pins, at least one cannulated sighting guide, a cannulated tool for rotating the fixing members and the sighting guide, also acting as a measuring instrument (for determining the length of at least some of the epiphyseal fixing members to be used), a cannulated drilling device (for drilling holes suitable for positioning at least some of the fixing members) and, preferably, an arthroscopic device designed to allow the practitioner to view some of the operative phases.Type: ApplicationFiled: April 29, 2021Publication date: August 24, 2023Inventors: Julien BALLERINI, Nicolas SMITH, Grégoire LARCHE, Jean-Pierre PODGORSKI
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Patent number: 11701008Abstract: Embodiments and aspects described herein provide methods and systems for determining pressure difference across a tube arising from fluid flow within the tube, comprising: obtaining three-dimensional time dependent fluid velocity data at a plurality of points along the tube; processing the three-dimensional time dependent fluid velocity data to determine: i) a flow rate (Q) of the fluid through the tube; ii) the kinetic energy (K) of the fluid flow through the tube; iii) an advective energy rate (A) of the fluid flow through the tube; and iv) a viscous dissipation rate (V) pertaining to the fluid flow; and calculating the pressure difference in dependence on all of the flow rate (Q), kinetic energy (K), advective energy rate (A), and viscous dissipation rate (V). Further embodiments are also described.Type: GrantFiled: September 21, 2021Date of Patent: July 18, 2023Assignee: King's College LondonInventors: Pablo Lamata De La Orden, David Nordsletten, Fabrizio Donati, Nicolas Smith
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Publication number: 20220306379Abstract: A garbage receptacle assembly includes a garbage can that has an open top end for having a garbage bag positioned therein. The garbage can has a front entry integrated therein to facilitate the garbage bag to be removed through the front entry without requiring the garbage bag to be lifted out of the garbage can. A door is hingedly coupled to the garbage can to close the front entry when the door is in a closed position. A plurality of clips is each integrated into the garbage can. The garbage bag can be suspended from the clips for retaining the garbage bag in an open position to enhance placing garbage in the garbage bag.Type: ApplicationFiled: March 24, 2021Publication date: September 29, 2022Inventor: Nicola Smith
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Publication number: 20220000372Abstract: Embodiments and aspects described herein provide methods and systems for determining pressure difference across a tube arising from fluid flow within the tube, comprising: obtaining three-dimensional time dependent fluid velocity data at a plurality of points along the tube; processing the three-dimensional time dependent fluid velocity data to determine: i) a flow rate (Q) of the fluid through the tube; ii) the kinetic energy (K) of the fluid flow through the tube; iii) an advective energy rate (A) of the fluid flow through the tube; and iv) a viscous dissipation rate (V) pertaining to the fluid flow; and calculating the pressure difference in dependence on all of the flow rate (Q), kinetic energy (K), advective energy rate (A), and viscous dissipation rate (V). Further embodiments are also described.Type: ApplicationFiled: September 21, 2021Publication date: January 6, 2022Inventors: Pablo Lamata De La Orden, David Nordsletten, Fabrizio Donati, Nicolas Smith
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Publication number: 20210363216Abstract: The present invention provides bifunctional binding polypeptide comprising a pMHC binding moiety and a PD-1 agonist.Type: ApplicationFiled: May 14, 2019Publication date: November 25, 2021Inventors: Giovanna BOSSI, Carlos REIS, Rajeevkumar TAWAR, Adam CURNOCK, Nicola SMITH
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Patent number: 11154205Abstract: Embodiments and aspects described herein provide a method of determining pressure difference across a tube arising from fluid flow within the tube, comprising: obtaining three-dimensional time dependent fluid velocity data at a plurality of points along the tube; processing the three-dimensional time dependent fluid velocity data to determine: i) a flow rate (Q) of the fluid through the tube; ii) the kinetic energy (K) of the fluid flow through the tube; iii) an advective energy rate (A) of the fluid flow through the tube; and iv) a viscous dissipation rate (V) pertaining to the fluid flow; and calculating the pressure difference in dependence on all of the flow rate (Q), kinetic energy (K), advective energy rate (A), and viscous dissipation rate (V). Further embodiments and aspects are also described.Type: GrantFiled: March 14, 2017Date of Patent: October 26, 2021Assignee: King's College LondonInventors: Pablo Lamata De La Orden, David Nordsletten, Fabrizio Donati, Nicolas Smith
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Publication number: 20190082970Abstract: Embodiments and aspects described herein provide a method of determining pressure difference across a tube arising from fluid flow within the tube, comprising: obtaining three-dimensional time dependent fluid velocity data at a plurality of points along the tube; processing the three-dimensional time dependent fluid velocity data to determine: i) a flow rate (Q) of the fluid through the tube; ii) the kinetic energy (K) of the fluid flow through the tube; iii) an advective energy rate (A) of the fluid flow through the tube; and iv) a viscous dissipation rate (V) pertaining to the fluid flow; and calculating the pressure difference in dependence on all of the flow rate (Q), kinetic energy (K), advective energy rate (A), and viscous dissipation rate (V). Further embodiments and aspects are also described.Type: ApplicationFiled: March 14, 2017Publication date: March 21, 2019Inventors: Pablo LAMATA DE LA ORDEN, David NORDSLETTEN, Fabrizio DONATI, Nicolas SMITH
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Publication number: 20180265274Abstract: The present disclosure relates to thermally insulating food packaging and more particularly to containers for storing or transporting food when the temperature of the food is significantly different to that of the surrounding environment. In particular, a food packaging material for enclosing food is described, the material including a first, moisture-permeable inner layer, a second, moisture-impermeable outer layer and a third, insulating moisture-tolerant layer disposed between the first and second layers and spacing the first and second layer apart, wherein the third layer has an undulating form including voids and wherein the first, second and third layers are arranged such that moisture emanating from food within the container passes through the first layer and the third layer and condenses on the second, moisture-impermeable outer layer.Type: ApplicationFiled: March 20, 2018Publication date: September 20, 2018Inventors: Keith Damarell, Nicola Smith
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Patent number: 9986966Abstract: The present invention provides a method for the determination of relative pressure fields from flow-sensitive data, the method comprising: applying a finite element discretization to the Pressure Poisson Equation (PPE): b = f + ?? ? ? u - ? ? ( ? u ? t + ( ( u - w ) · ? ) ? u ) where vecter b is a function of a given blood velocity data, u represents the velocity, w the reference velocity, t the time, f a volume force, p the pressure and ? and ? the fluid density and viscosity, respectively, and wherein the PPE is now defined as the divergence of the above equation and gives a higher order derivative of the pressure field p: ?p=?·b.Type: GrantFiled: December 3, 2013Date of Patent: June 5, 2018Assignee: OXFORD UNIVERSITY INNOVATION LIMITEDInventors: Sebastian Benedikt Sylvester Krittian, Nicolas Smith
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Patent number: 9066446Abstract: Thermal extraction architectures for heat-generating electronic devices such as cameras or lights are disclosed. An electronic device such as a camera head may include a housing, a printed circuit board (PCB) within the housing, and a thermal extraction element positioned between the housing and PCB to transfer heat from the PCB to the housing and external environment.Type: GrantFiled: February 22, 2013Date of Patent: June 23, 2015Assignee: Seescan, Inc.Inventors: Mark S. Olsson, Eric M. Chapman, Nicolas A. Smith
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Publication number: 20140222354Abstract: The present invention provides a method for the determination of relative pressure fields from flow-sensitive data, the method comprising: applying a finite element discretisation to the Pressure Poisson Equation (PPE): b = f + ?? ? ? u - ? ? ( ? u ? t + ( ( u - w ) · ? ) ? u ) where vecter b is a function of a given blood velocity data, u represents the velocity, w the reference velocity, t the time, f a volume force, p the pressure and p and ? the fluid density and viscosity, respectively, and wherein the PPE is now defined as the divergence of the above equation and gives a higher order derivative of the pressure field p: ?p=?·b.Type: ApplicationFiled: December 3, 2013Publication date: August 7, 2014Applicant: ISIS INNOVATION LTD.Inventors: Sebastian Benedikt Sylvester KRITTIAN, Nicolas Smith