Patents by Inventor Nicolas Ugolin

Nicolas Ugolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080182758
    Abstract: The invention relates to a method of analysing molecular targets contained in a complex mixture, comprising the following steps consisting in: a) bringing the mixture of molecular targets to be analysed into contact with an array of different types of primary probes, whereby each type of primary probe forming the array can bind specifically to a type of target selected from among the molecular targets, under conditions that enable specific binding between the molecular targets and the primary probes; b) optionally eliminating the primary probes that are not bound specifically to a molecular target; c) separating the molecular targets and the primary probes which are bound specifically in a probe/target complex, such as to recover the array of primary probes representing a fingerprint of the molecular targets to be analysed; and d) quantitatively analysing the primary probes eluted in step c.
    Type: Application
    Filed: August 24, 2007
    Publication date: July 31, 2008
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Nicolas Ugolin, Sylvie Chevillard, Alexandre Coutant, Jerome Lebeau
  • Patent number: 7136517
    Abstract: The invention relates to an image analysis process for measuring the signal on biochips organized into one or several blocks each comprising a large number of spots each composed of at least one probe, the said process being characterized in that it comprises the following steps: a deposit is made with a constant pitch, the spots appearing in the form of a periodic and regular signal; this periodicity property is used to identify the position of the blocks and the spots, this periodicity being searched for on projections of the image in the x and y directions.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: November 14, 2006
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Nicolas Ugolin, Mory Doukoure, Olivier Alibert, Sylvie Chevillard
  • Publication number: 20060239864
    Abstract: The invention relates to a device for separating and/analyzing several molecular targets dissolved in a complex mixture which is characterized in that it comprises a) a matrix of micro-columns, wherein each micro-column (2) comprises an immobilized molecular probe for retaining a specific molecular target contained in the complex mixture by specific probe/target linkage, b) a first capillary network (3) for circulating the complex mixture introduced into the inventive device towards each micro-column of the matrix defined in a), c) a second capillary network (4) for circulating, after elution, the molecular targets retained on the micro-columns towards a sensor (5) for carrying out the recovery and/or analysis thereof, and d) if necessary, a sensor (5), preferably in the form of a mass spectrometer, for carrying out the recovery and/or analysis of different molecular targets.
    Type: Application
    Filed: March 23, 2006
    Publication date: October 26, 2006
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Nicolas Ugolin, Sylvie Chevillard, Catherine Ory, Jerome Lebeau
  • Publication number: 20040106121
    Abstract: The invention relates to an organized array of biological or chemical probes bonded to a support by magnetic coupling using a fixing vector. The support may include a permanent magnet or present electrically-induced magnetization. The fixing vectors may be constituted by magnetic beads functionalized to be capable of bonding specifically to one particular type of biological probe.
    Type: Application
    Filed: May 23, 2003
    Publication date: June 3, 2004
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Nicolas Ugolin, Gerard Marguerie De Rotrou, Thierry Kortulewski, Olivier Alibert, Diana Le Roux
  • Publication number: 20040001623
    Abstract: The invention relates to an image analysis process for measuring the signal on biochips organized into one or several blocks each comprising a large number of spots each composed of at least one probe, the said process being characterized in that it comprises the following steps:
    Type: Application
    Filed: June 19, 2002
    Publication date: January 1, 2004
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Nicolas Ugolin, Mory Doukoure, Olivier Alibert, Sylvie Chevillard