Patents by Inventor Nicole Cathleen Goodwin

Nicole Cathleen Goodwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ether linked triazoles as NRF2 activators
    Patent number: 12091409
    Abstract: The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: September 17, 2024
    Assignee: ASTEX THERAPEUTICS LIMITED
    Inventors: Anthony William James Cooper, Nicole Cathleen Goodwin, Charlotte Mary Griffiths-Jones, Thomas Daniel Heightman, Jeffrey K. Kerns, Hendrika Maria Gerarda Willems, Hongxing Yan
  • Nrf2 REGULATORS
    Publication number: 20230047296
    Abstract: The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: October 6, 2021
    Publication date: February 16, 2023
    Inventors: Jeffrey K. KERNS, James Callahan, Hongxing Yan, Thomas Daniel Heightman, Charlotte Mary Griffiths-Jones, Alison Jo-Anne Woolford, Tindy Li, Ami Lakdawala Shah, Roderick S. Davis, David Norton, Jeffrey Charles Boehm, Paris L. Hamilton, Nicole Cathleen Goodwin, Yun Jin
  • ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS
    Publication number: 20220089590
    Abstract: The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Application
    Filed: June 17, 2021
    Publication date: March 24, 2022
    Inventors: Anthony William James Cooper, Nicole Cathleen Goodwin, Charlotte Mary Griffiths-Jones, Thomas Daniel Heightman, Jeffrey K. Kerns, Hendrika Maria Gerarda Willems, Hongxing Yan
  • BISARYL LACTAMS AS NRF2 ACTIVATORS
    Publication number: 20220002272
    Abstract: The present invention relates to bisaryl lactam compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Application
    Filed: December 11, 2017
    Publication date: January 6, 2022
    Inventors: Jeffrey Charles BOEHM, Roderick S. DAVIS, Nicole Cathleen GOODWIN, Jeffrey K. KERNS, Tindy LI, Hongxing YAN
  • Bisaryl heterocycles as NRF2 activators
    Patent number: 11117905
    Abstract: The present invention relates to bisaryl heterocycle compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: September 14, 2021
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: James Francis Callahan, Roderick S. Davis, Nicole Cathleen Goodwin, Jeffrey K. Kerns
  • Bisaryl amides as NRF2 activators
    Patent number: 11078216
    Abstract: The present invention relates to bisaryl amide analogs, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: August 3, 2021
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: James Francis Callahan, Vincent J. Colandrea, Anthony William James Cooper, Nicole Cathleen Goodwin, Chelsea Ariane Huff, Joel Karpiak, Jeffrey K. Kerns, Hong Nie
  • Ether linked triazoles as NRF2 activators
    Patent number: 11059816
    Abstract: The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: July 13, 2021
    Assignees: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, ASTEX THERAPEUTICS LIMITED
    Inventors: Anthony William James Cooper, Nicole Cathleen Goodwin, Charlotte Mary Griffiths-Jones, Thomas Daniel Heightman, Jeffrey K. Kerns, Hendrika Maria Gerarda Willems, Hongxing Yan
  • Nrf2 regulators
    Patent number: 10604509
    Abstract: Provided are aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: March 31, 2020
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, Astex Therapeutics Limited
    Inventors: Jeffrey K. Kerns, James Callahan, Thomas Daniel Heightman, Alison Jo-Anne Woolford, Ami Lakdawala Shah, Roderick S. Davis, David Norton, Jeffrey Charles Boehm, Nicole Cathleen Goodwin
  • Nrf2 REGULATORS
    Publication number: 20200079759
    Abstract: The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 12, 2020
    Inventors: Jeffrey K. KERNS, James Callahan, Hongxing Yan, Thomas Daniel Heightman, Charlotte Mary Griffiths-Jones, Alison Jo-Anne Woolford, Tindy Li, Ami Lakdawala Shah, Roderick S. Davis, David Norton, Jeffrey Charles Boehm, Paris L. Hamilton, Nicole Cathleen Goodwin, Yun Jin
  • ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS
    Publication number: 20200071317
    Abstract: The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Application
    Filed: December 11, 2017
    Publication date: March 5, 2020
    Inventors: Anthony William James COOPER, Nicole Cathleen GOODWIN, Charlotte Mary GRIFFITHS-JONES, Thomas Daniel HEIGHTMAN, Jeffrey K. KERNS, Hendrika Maria Gerarda WILLEMS, Hongxing YAN
  • BISARYL HETEROCYCLES AS NRF2 ACTIVATORS
    Publication number: 20200062781
    Abstract: The present invention relates to bisaryl heterocycle compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Application
    Filed: December 11, 2017
    Publication date: February 27, 2020
    Inventors: James Francis CALLAHAN, Roderick S. DAVIS, Nicole Cathleen GOODWIN, Jeffrey K. KERNS
  • BISARYL AMIDES AS NRF2 ACTIVATORS
    Publication number: 20190330238
    Abstract: The present invention relates to bisaryl amide analogs, pharmaceutical compositions containing them and their use as NRF2 activators.
    Type: Application
    Filed: December 11, 2017
    Publication date: October 31, 2019
    Inventors: James Francis CALLAHAN, Vincent J. COLANDREA, Anthony William James COOPER, Nicole Cathleen GOODWIN, Chelsea Ariane HUFF, Joel KARPIAK, Jeffrey K. KERNS, Hong NIE
  • Inhibitors of sodium glucose transporter 1 for constipation
    Patent number: 10106569
    Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: October 23, 2018
    Assignee: Lexicon Pharmaceutical, Inc.
    Inventors: Kenneth Gordon Carson, Nicole Cathleen Goodwin, Bryce Alden Harrison, David Brent Rawlins, Eric Strobel, Brian Zambrowicz
  • INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1
    Publication number: 20180244708
    Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.
    Type: Application
    Filed: May 22, 2017
    Publication date: August 30, 2018
    Inventors: Kenneth Gordon CARSON, Nicole Cathleen GOODWIN, Bryce Alden HARRISON, David Brent RAWLINS, Eric STROBEL, Brian ZAMBROWICZ
  • Inhibitors of sodium glucose cotransporter 1
    Patent number: 9688710
    Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: June 27, 2017
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Kenneth Gordon Carson, Nicole Cathleen Goodwin, Bryce Alden Harrison, David Brent Rawlins, Eric Strobel, Brian Zambrowicz
  • INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1
    Publication number: 20160326205
    Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.
    Type: Application
    Filed: November 17, 2015
    Publication date: November 10, 2016
    Inventors: Kenneth Gordon CARSON, Nicole Cathleen GOODWIN, Bryce Alden HARRISON, David Brent RAWLINS, Eric STROBEL, Brian ZAMBROWICZ
  • Inhibitors of sodium glucose cotransporter 1
    Patent number: 9200025
    Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: December 1, 2015
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Kenneth Gordon Carson, Nicole Cathleen Goodwin, Bryce Alden Harrison, David Brent Rawlins, Eric Strobel, Brian Zambrowicz
  • INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1
    Publication number: 20140309178
    Abstract: Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes are disclosed. Particular compounds are of the formula: the various substituents of which are defined herein.
    Type: Application
    Filed: November 18, 2013
    Publication date: October 16, 2014
    Applicant: LEXICON PHARMACEUTICALS, INC.
    Inventors: Kenneth Gordon CARSON, Nicole Cathleen GOODWIN, Bryce Alden HARRISON, David Brent RAWLINS, Eric STROBEL, Brian ZAMBROWICZ
  • LIMK2 inhibitors, compositions comprising them, and methods of their use
    Patent number: 8450332
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: May 28, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • 5-(1H-PYRAZOL-5-YL)THIAZOLE-BASED COMPOUNDS FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE EYE
    Publication number: 20130059896
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Application
    Filed: January 21, 2011
    Publication date: March 7, 2013
    Inventors: Nicole Cathleen Goodwin, David Brent Rawlins