Patents by Inventor NIELS BOEHNKE
NIELS BOEHNKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240109860Abstract: The invention relates to novel compounds of the formula (I) in which Z, Y, A1, A2, A3, A4, X, R7, R8 and R9 have the meanings mentioned above, and processes and intermediates for the preparation thereof, and their use for controlling animal pests, in particular insects.Type: ApplicationFiled: October 20, 2023Publication date: April 4, 2024Inventors: Robert VELTEN, Alexander ARLT, Niels BOEHNKE, Kerstin ILG, Sebastian HORSTMANN, Arnoldus VERMEER, Karin HORN, Ulrich GOERGENS, Daniela PORTZ, Andreas TURBERG
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Patent number: 11827616Abstract: The invention relates to novel compounds of the formula (I) in which Z, Y, A1, A2, A3, A4, X, R7, R8 and R9 have the meanings mentioned above, and processes and intermediates for the preparation thereof, and their use for controlling animal pests, in particular insects.Type: GrantFiled: April 26, 2018Date of Patent: November 28, 2023Assignee: DISCOVERY PURCHASER CORPORATIONInventors: Robert Velten, Alexander Arlt, Niels Boehnke, Kerstin Ilg, Sebastian Horstmann, Arnoldus Vermeer, Karin Horn, Ulrich Goergens, Daniela Portz, Andreas Turberg
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Publication number: 20230072421Abstract: A compound of general formula (I): wherein: n is 1, 2 or 3; R1, R2, R3 and R4, independently represent OH or Q; and 20 Q represents a tissue-targeting moeity selected from the group consisting of or a stereoisomer, a hydrate, a solvate, or a salt thereof, or a mixture of same, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said 25 compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of soft tissue diseases, as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: July 24, 2020Publication date: March 9, 2023Applicants: Bayer AS, Bayer AktiengesellschaftInventors: Niels BÖHNKE, Sabine ZITZMANN-KOLBE, Stefanie HAMMER, Sven WITTROCK, Donald BIERER, Thorsten POETHKO, Hans BRIEM, Holger Magnus STEUBER, Martina SCHÄFER, Robin Michael MEIER, Arif CELIK, Cornelia PREUSSE, Antje ROTTMANN, Nicolas WERBECK, Alexander KRISTIAN, Bård INDREVOLL, Alan CUTHBERTSON, Alex PAPPLE
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Publication number: 20220274979Abstract: The present invention covers 2-methyl-aza-quinazoline compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredientsType: ApplicationFiled: April 15, 2019Publication date: September 1, 2022Applicants: Bayer Pharma Aktiengesellschaft, Bayer Healthcare ChinaInventors: Lars WORTMANN, Brice SAUTIER, Knut EIS, Hans BRIEM, Niels BÖHNKE, Franz VON NUSSBAUM, Roman HILIG, Benjamin BADER, Jens SCHRÖDER, Kirstin PETERSEN, Philip LIENAU, Antje Margret WENGNER, Dieter MOOSMAYER, Qiuwen WANG, Hans SCHICK
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Publication number: 20200360531Abstract: Conjugate of a binder having formula: (A) wherein stands for a binder, Z? stands for a linker and D stands for an active component of Formula (I): and its use as pharmaceuticals.Type: ApplicationFiled: January 25, 2019Publication date: November 19, 2020Applicants: Bayer Aktiengesellschaft, Bayer Pharma AktiengesellschaftInventors: Niels BÖHNKE, Markus BERGER, Anette SOMMER, Stefanie HAMMER, Amaury Ernesto FERNANDEZ-MONTALVAN, Beatrix STELTE-LUDWIG, Judith GÜNTHER, Christoph MAHLERT, Simone GREVEN, Abul Basher SARKER, Michael TAIT
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Publication number: 20200062729Abstract: The invention relates to novel compounds of the formula (I) in which Z, Y, A1, A2, A3, A4, X, R7, R8 and R9 have the meanings mentioned above, and processes and intermediates for the preparation thereof, and their use for controlling animal pests, in particular insects.Type: ApplicationFiled: April 26, 2018Publication date: February 27, 2020Inventors: Robert VELTEN, Alexander ARLT, Niels BOEHNKE, Kerstin ILG, Sebastian HORSTMANN, Arnoldus VERMEER, Karin HORN, Ulrich GOERGENS, Daniela PORTZ, Andreas TURBERG
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Patent number: 10150737Abstract: The invention relates inter alia to compounds of the general formula (I) in which the A1-A4, T, n, W, Q, R1 and B1-B4 radicals are each as defined in the description. Also described are processes for preparing the compounds of the formula (I). The inventive compounds are especially suitable for controlling insects, arachnids and nematodes in agriculture, and ectoparasites in veterinary medicine.Type: GrantFiled: November 5, 2014Date of Patent: December 11, 2018Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFTInventors: Werner Hallenbach, Hans-Georg Schwarz, Kerstin Ilg, Ulrich Goergens, Johannes Koebberling, Andreas Turberg, Niels Boehnke, Michael Maue, Robert Velten, Tobias Harschneck, Julia Johanna Hahn, Sebastian Horstmann
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Patent number: 9936699Abstract: The invention relates inter alia to halogen-substituted compounds of the general formula (I) in which the substituents A1, R1-R3 and Z1-Z3 have the meanings given in the description. Also described are processes for preparing the compounds of the formula (I) and possible intermediates for the preparation of these compounds. The compounds according to the invention are particularly suitable for controlling insects, arachnids and nematodes in agriculture and ectoparasites in veterinary medicine.Type: GrantFiled: August 5, 2015Date of Patent: April 10, 2018Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFTInventors: Michael Maue, Tobias Harschneck, Julia Johanna Hahn, Thomas Bretschneider, Anne Decor, Reiner Fischer, Werner Hallenbach, Hans-Georg Schwarz, Robert Velten, Niels Böhnke, Olga Malsam, Ulrich Görgens, Sebastian Horstmann, Klaus Raming, Johannes Köbberling, Walter Hübsch
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Patent number: 9877954Abstract: The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: GrantFiled: April 3, 2017Date of Patent: January 30, 2018Assignee: Bayer Pharma AktiengesellschaftInventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn
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Patent number: 9758485Abstract: The invention relates inter alia to compounds of the general formula (I) in which the A1-A4, T, n, W, Q, R1 and B1-B4 radicals are each as defined in the description. Also described are processes for preparing the compounds of the formula (I). The inventive compounds are especially suitable for controlling insects, arachnids and nematodes in agriculture, and ectoparasites in veterinary medicine.Type: GrantFiled: November 5, 2014Date of Patent: September 12, 2017Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFTInventors: Werner Hallenbach, Hans-Georg Schwarz, Kerstin Ilg, Ulrich Goergens, Johannes Koebberling, Andreas Turgerg, Niels Boehnke, Michael Maue, Robert Velten, Tobias Harschneck, Julia Johanna Hahn, Sebastian Horstmann
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Publication number: 20170223960Abstract: The invention relates inter alia to halogen-substituted compounds of the general formula (I) in which the substituents A1, R1-R3 and Z1-Z3 have the meanings given in the description. Also described are processes for preparing the compounds of the formula (I) and possible intermediates for the preparation of these compounds. The compounds according to the invention are particularly suitable for controlling insects, arachnids and nematodes in agriculture and ectoparasites in veterinary medicine.Type: ApplicationFiled: August 5, 2015Publication date: August 10, 2017Inventors: Michael MAUE, Tobias HARSCHNECK, Julia Johanna HAHN, Thomas BRETSCHNEIDER, Anne DECOR, Reiner FISCHER, Werner HALLENBACH, Hans-Georg SCHWARZ, Robert VELTEN, Niels BÖHNKE, Olga MALSAM, Ulrich GÖRGENS, Sebastian HORSTMANN, Klaus RAMING, Johannes KÖBBERLING, Walter HÜBSCH
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Publication number: 20170202815Abstract: The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: ApplicationFiled: April 3, 2017Publication date: July 20, 2017Applicant: Bayer Pharma AktiengesellschaftInventors: Ulrich LÜCKING, Niels BÖHNKE, Arne SCHOLZ, Philip LIENAU, Gerhard SIEMEISTER, Ulf BÖMER, Dirk KOSEMUND, Rolf BOHLMANN, Ludwig ZORN
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Patent number: 9708293Abstract: The present invention relates to N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfone group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: GrantFiled: October 16, 2013Date of Patent: July 18, 2017Assignee: Bayer Pharma AktiengesellschaftInventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn
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Patent number: 9670161Abstract: The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: GrantFiled: October 15, 2013Date of Patent: June 6, 2017Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn
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Patent number: 9650340Abstract: The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: GrantFiled: November 12, 2013Date of Patent: May 16, 2017Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn
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Patent number: 9650361Abstract: The present invention relates to disubstituted N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: GrantFiled: November 13, 2013Date of Patent: May 16, 2017Assignee: BAYER PHARAM AKTIENGESELLSCHAFTInventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn
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Publication number: 20160297765Abstract: The invention relates inter alia to compounds of the general formula (I) in which the A1-A4, T, n, W, Q, R1 and B1-B4 radicals are each as defined in the description. Also described are processes for preparing the compounds of the formula (I). The inventive compounds are especially suitable for controlling insects, arachnids and nematodes in agriculture, and ectoparasites in veterinary medicine.Type: ApplicationFiled: November 5, 2014Publication date: October 13, 2016Inventors: WERNER HALLENBACH, HANS-GEORG SCHWARZ, KERSTIN ILG, ULRICH GOERGENS, JOHANNES KOEBBERLING, ANDREAS TURGERG, NIELS BOEHNKE, MICHAEL MAUE, ROBERT VELTEN, TOBIAS HARSCHNECK, JULIA JOHANNA HAHN, SEBASTIAN HORSTMANN
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Publication number: 20160278379Abstract: The invention relates inter alia to compounds of the general formula (I) in which the A1-A4, T, n, W, Q, R1 and B1-B4 radicals are each as defined in the description. Also described are processes for preparing the compounds of the formula (I). The inventive compounds are especially suitable for controlling insects, arachnids and nematodes in agriculture, and ectoparasites in veterinary medicine.Type: ApplicationFiled: November 5, 2014Publication date: September 29, 2016Inventors: WERNER HALLENBACH, HANS-GEORG SCHWARZ, KERSTIN ILG, ULRICH GOERGENS, JOHANNES KOEBBERLING, ANDREAS TURGERG, NIELS BOEHNKE, MICHAEL MAUE, ROBERT VELTEN, TOBIAS HARSCHNECK, JULIA JOHANNA HAHN, SEBASTIAN HORSTMANN
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Publication number: 20150291528Abstract: The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: ApplicationFiled: November 12, 2013Publication date: October 15, 2015Applicant: BAYER PHARMA AKTIEGESELLSCHAFTInventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn
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Publication number: 20150291559Abstract: The present invention relates to disubstituted N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).Type: ApplicationFiled: November 13, 2013Publication date: October 15, 2015Inventors: Ulrich Lücking, Niels Böhnke, Arne Scholz, Philip Lienau, Gerhard Siemeister, Ulf Bömer, Dirk Kosemund, Rolf Bohlmann, Ludwig Zorn