Patents by Inventor Niels Bukh

Niels Bukh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5916880
    Abstract: Use of a sulphated saccharide or a salt or complex thereof for the preparation of a medicament for topical application to the skin or to any non-gastrointestinal, non-oral mucosal surface of an animal or a human, including the lining of body cavities, or for injection into tissue, including joints, or implantation into surgical wounds or a body cavity of an animal or a human, for the prophylaxis or treatment of any manifestation of inflammation or infection, for the prophylaxis or treatment of non-bladder premalignant or malignant disorders, for the prophylaxis or treatment of irritation or burns of the skin, connective tissue, or non-oral mucosa, or for the prophylaxis or treatment of skin, connective tissue, or mucosal aging, or for the preparation of a medicament for systemic injection for the treatment or prophylaxis of infectious, malignant or allergic/immune disorders. The sulphated saccharide, e.g.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 29, 1999
    Assignee: Bukh Meditec A/S
    Inventors: Daniel Bar-Shalom, Niels Bukh
  • Patent number: 5908836
    Abstract: Use of a sulphated saccharide or a salt or complex thereof for the preparation of a medicament for topical application to the skin or to any non-gastrointestinal, non-oral mucosal surface of an animal or a human, including the lining of body cavities, or for injection into tissue, including joints, or implantation into surgical wounds or a body cavity of an animal or a human, for the prophylaxis or treatment of any manifestation of inflammation or infection, for the prophylaxis or treatment of non-bladder premalignant or malignant disorders, for the prophylaxis or treatment of irritation or burns of the skin, connective tissue, or non-oral mucosa, or for the prophylaxis or treatment of skin, connective tissue, or mucosal aging, or for the preparation of a medicament for systemic injection for the treatment or prophylaxis of infectious, malignant or allergic/immune disorders. The sulphated saccharide, e.g.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 1, 1999
    Inventors: Daniel Bar-Shalom, Niels Bukh
  • Patent number: 5767104
    Abstract: A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a sulfated mono-, di- or oligosaccharide or a derivative, salt or complex thereof. The saccharide is preferably polysulfated, such as a polysulfated disaccharide, in particular sucrose, or a derivative, complex or salt thereof. Especially interesting polusulfated disaccharides are sucrose pentasulfate, sucrose hexasulfate, sucrose heptasulfate and sucrose octasulfate, e.g. in the form of a potassium or sodium salt, or in the form of sucralfate.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: June 16, 1998
    Inventors: Daniel Bar-Shalom, Niels Bukh
  • Patent number: 5709873
    Abstract: The use of a sulphated saccharide or a salt or a complex thereof as an ingredient in a topical preparation for the prophylaxis or treatment of diseases or conditions of the tooth or tooth-supporting tissue, in particular for the prophylaxis or treatment of inflammatory and plaque-related conditions, a method of preventing or treating such diseases or conditions by topically applying the sulphated saccharide or salt or complex thereof, and a topical preparation containing the sulphated saccharide or salt or complex thereof for the prophylaxis or treatment of such diseases or conditions. The sulphated saccharide is especially a polysulphated or persulphated saccharide, e.g. sucralfate (sucrose octakis(hydrogen sulphate) aluminum complex) or a sodium and/or potassium salt of sucrose octakis(hydrogen sulphate). The preparation may be in the form of a solution, suspension, salve, paste, powder, gel, cream, dental fixative, periodontal implant, chewing gum, chewable tablet, effervescent tablet or lozenge.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 20, 1998
    Assignee: Niels Bukh A/S
    Inventors: Daniel Bar-Shalom, Niels Bukh, Jesper Hamburger
  • Patent number: 5618798
    Abstract: A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a sulfated mono-, di- or oligosaccharide or a derivative, salt or complex thereof. The saccharide is preferably polysulfated, such as a polysulfated disaccharide, in particular sucrose, or a derivative, complex or salt thereof. Especially interesting polysulfated disaccharides are sucrose pentasulfate, sucrose hexasulfate, sucrose heptasulfate and sucrose octasulfate, e.g. in the form of a potassium or sodium salt, or in the form of sucralfate.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: April 8, 1997
    Inventors: Daniel Bar-Shalom, Niels Bukh
  • Patent number: 5567431
    Abstract: Implantable poly(lactic acid)-based pharmaceutical composition which comprises at least one water soluble antibiotic in particle form with controlled dimensions, less than 100 .mu.m uniformly dispersed in an amorphous poly(lactic acid) matrix, said composition being in ground powder or thin film form. Application especially in initiating local internal antibiotic therapy by the gradual release of the antibiotic substance.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: October 22, 1996
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: Michel Vert, Jacques Mauduit, Niels Bukh
  • Patent number: 5240710
    Abstract: The use of a sulphated saccharide or a salt or a complex thereof as an ingredient in a topical preparation for the prophylaxis or treatment of diseases or conditions of the tooth or tooth-supporting tissue, in particular for the prophylaxis or treatment of inflammatory and plaque-related conditions, a method of preventing or treating such diseases or conditions by topically applying the sulphated saccharide or salt or complex thereof, and a topical preparation containing the sulphated saccharide or salt or complex thereof for the prophylaxis or treatment of such diseases or conditions. The sulphated saccharide is especially a polysulphated or persulphated saccharide. e.g. sucralfate (sucrose octakis(hydrogen sulphate) aluminum complex) or a sodium and/or potassium salt of sucrose octakis(hydrogen sulphate). The preparation may be in the form of a solution, suspension, salve, paste, powder, gel, cream, dental fixative, periodontal implant, chewing gum, chewable tablet, effervescent tablet or lozenge.
    Type: Grant
    Filed: September 4, 1992
    Date of Patent: August 31, 1993
    Assignees: Niels Bukh, Tandlaegeselskabet Jesper Hamberger ApS
    Inventors: Daniel K. Bar-Shalom, Niels Bukh, Jesper Hamburger