Patents by Inventor Niels Grabe

Niels Grabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CCR5 ANTAGONISTS ALONE OR IN COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20210000816
    Abstract: The present invention relates to CCRS antagonists for use in the treatment of cancer, either in monotherapy or in combination therapy. The invention also relates to methods for determining whether a subject suffering from cancer benefits from an ongoing therapeutic treatment with a CCRS antagonist or whether a subject suffering from cancer will benefit from a planned therapeutic treatment with a CCRS antagonist.
    Type: Application
    Filed: July 20, 2020
    Publication date: January 7, 2021
    Inventors: Niels HALAMA, Dirk JAGER, Inka ZOERNIG, Niels GRABE
  • USE OF CCR5 ANTAGONISTS ALONE OR IN COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20180289689
    Abstract: The present invention relates to CCRS antagonists for use in the treatment of cancer, either in monotherapy or in combination therapy. The invention also relates to methods for determining whether a subject suffering from cancer benefits from an ongoing therapeutic treatment with a CCRS antagonist or whether a subject suffering from cancer will benefit from a planned therapeutic treatment with a CCRS antagonist.
    Type: Application
    Filed: October 27, 2015
    Publication date: October 11, 2018
    Inventors: Niels HALAMA, Dirk JÄGER, Inka ZOERNIG, Niels GRABE
  • Means and methods for the prediction of treatment response of a cancer patient
    Patent number: 9726676
    Abstract: The present invention relates to the field of treatment efficacy prediction in patients with malignant diseases. More precisely, this invention relates to the prediction of the efficacy of a treatment in cancer patients, based on the precise quantification of several biological markers that are related to the innate and adaptive immune response of said patient against said cancer.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: August 8, 2017
    Inventors: Niels Grabe, Niels Halama, Dirk Jaeger, Inka Zoernig
  • MEANS AND METHODS FOR THE PREDICTION OF TREATMENT RESPONSE OF A CANCER PATIENT
    Publication number: 20130330325
    Abstract: The present invention relates to the field of treatment efficacy prediction in patients with malignant diseases. More precisely, this invention relates to the prediction of the efficacy of a treatment in cancer patients, based on the precise quantification of several biological markers that are related to the innate and adaptive immune response of said patient against said cancer.
    Type: Application
    Filed: September 20, 2011
    Publication date: December 12, 2013
    Inventors: Niels Grabe, Niels Halama
  • Method for the detection of a functional protein sequence and an apparatus therefor
    Publication number: 20040023300
    Abstract: The present invention concerns a method and a system for the prediction of short functional significant protein sequences. In particular, the invention is related to a method of predicting phosphorylation sites in protein sequences. The invention is based on a case-based, on-the-fly model generation for prediction. The invention is described by the example of predicting phosphorylation sites in unknown protein sequences but is applicable for the prediction of any functional significant protein sequence in a longer protein sequence to be analysed.
    Type: Application
    Filed: February 12, 2003
    Publication date: February 5, 2004
    Inventors: Niels Grabe, Matthias Konig