Patents by Inventor Niels Skjærbæk

Niels Skjærbæk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Suplatast tosilate for use in the treatment of cough associated with interstitial lung disease
    Patent number: 11690814
    Abstract: Provided is a composition comprising suplatast tosilate or pharmaceutically acceptable derivatives thereof for use in a method of treating cough associated with interstitial lung disease, such as cough associated with pulmonary fibrosis.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: July 4, 2023
    Assignee: CONRIG PHARMA APS
    Inventors: John Bondo Hansen, Mikael S. Thomsen, Niels Skjærbæk
  • SUPLATAST TOSILATE FOR USE IN THE TREATMENT OF COUGH ASSOCIATED WITH INTERSTITIAL LUNG DISEASE
    Publication number: 20190254998
    Abstract: Provided is a composition comprising suplatast tosilate or pharmaceutically acceptable derivatives thereof for use in a method of treating cough associated with interstitial lung disease, such as cough associated with pulmonary fibrosis.
    Type: Application
    Filed: November 16, 2016
    Publication date: August 22, 2019
    Inventors: John Bondo Hansen, Mikael S. Thomsen, Niels Skjærbæk
  • Tetrahydroquinoline analogues as muscarinic agonists
    Patent number: 9522906
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: December 20, 2016
    Assignee: ACADIA PHARMACEUTICALS, INC.
    Inventors: Niels Skjaerbaek, Kristian Norup Koch, Bo Lennart Mikael Friberg, Bo-Ragnar Tolf
  • TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS
    Publication number: 20140221364
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Application
    Filed: February 5, 2014
    Publication date: August 7, 2014
    Applicant: ACADIA PHARMACEUTICALS, INC.
    Inventors: NIELS SKJAERBAEK, KRISTIAN NORUP KOCH, BO LENNART MIKAEL FRIBERG, BO-RAGNAR TOLF
  • Tetrahydroquinoline analogues as muscarinic agonists
    Patent number: 7576078
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: August 18, 2009
    Assignee: Acadia Pharmaceuticals, Inc.
    Inventors: Niels Skjaerbaek, Kristian Norup Koch, Bo Lennart Mikael Friberg, Bo-Ragnar Tolf
  • Muscarinic agonists
    Patent number: 7576100
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: August 18, 2009
    Assignee: Acadia Pharmaceuticals, Inc.
    Inventors: Niels Skjaerbaek, Kristian Norup Koch, Bo Lennart Mikael Friberg, Bo-Ragnar Tolf
  • Tetrahydroquinoline analogues as muscarinic agonists
    Patent number: 7550459
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: June 23, 2009
    Assignee: Acadia Pharmaceuticals, Inc.
    Inventors: Niels Skjaerbaek, Kristian Norup Koch, Bo Lennart Mikael Friberg, Bo-Ragnar Tolf
  • Compounds with activity on muscarinic receptors
    Patent number: 7485651
    Abstract: Compounds and methods are provided for the alleviation or treatment of diseases or conditions in which modification of muscarinic m1 receptor activity has a beneficial effect. In the method, a therapeutically effective amount of a selective muscarinic m1 agonist compound is administered to a patient in need of such treatment.
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: February 3, 2009
    Assignee: Acadia Pharmaceuticals, Inc.
    Inventors: Mark Brann, Terri Messier, Erika Currier, Kate Duggento, Tracy Spalding, Mikael Friberg, Niels Skjaerbaek
  • COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS
    Publication number: 20080108618
    Abstract: Compounds and methods are provided for the alleviation or treatment of diseases or conditions in which modification of muscarinic m1 receptor activity has a beneficial effect. In the method, a therapeutically effective amount of a selective muscarinic m1 agonist compound is administered to a patient in need of such treatment.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Inventors: Mark Brann, Terri Messier, Erika Currier, Kate Duggento, Tracy Spalding, Mikael Friberg, Niels Skjaerbaek
  • Tetrahydroquinoline analogues as muscarinic agonists
    Patent number: 7307075
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: December 11, 2007
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Niels Skjaerbaek, Kristian Norup Koch, Bo Lennart Mikael Friberg, Bo-Ragnar Tolf
  • MUSCARINIC AGONISTS
    Publication number: 20070155795
    Abstract: Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.
    Type: Application
    Filed: February 16, 2007
    Publication date: July 5, 2007
    Applicant: ACADIA Pharmaceuticals Inc.
    Inventors: Carl-Magnus Andersson, Bo Lennart Friberg, Niels Skjaerbaek, Tracy Spalding, Allan Uldam
  • Muscarinic agonists
    Patent number: 7238713
    Abstract: Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: July 3, 2007
    Assignee: Acadia Pharmaceuticals, Inc.
    Inventors: Carl-Magnus A. Anderson, Bo Lennart M. Friberg, Niels Skjaerbaek, Tracy A. Spalding, Allan K. Uldam
  • Muscarinic agonists
    Publication number: 20060199810
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Application
    Filed: May 3, 2006
    Publication date: September 7, 2006
    Inventors: Niels Skjaerbaek, Kristian Koch, Bo Lennart Friberg, Bo-Ragnar Tolf
  • Tetrahydroquinoline analogues as muscarinic agonists
    Publication number: 20050209226
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Application
    Filed: December 21, 2004
    Publication date: September 22, 2005
    Inventors: Niels Skjaerbaek, Kristian Koch, Bo Mikael Friberg, Bo-Ragnar Tolf
  • Muscarinic agonists
    Publication number: 20050113357
    Abstract: Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.
    Type: Application
    Filed: July 17, 2003
    Publication date: May 26, 2005
    Inventors: Carl-Magnus Anderson, Bo Friberg, Niels Skjaerbaek, Tracy Spalding, Allan Uldam
  • Muscarinic agonists
    Patent number: 6627645
    Abstract: Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: September 30, 2003
    Assignee: Acadia Pharmaceuticals, Inc.
    Inventors: Carl-Magnus A. Andersson, Bo Lennart M. Friberg, Niels Skjaerbaek, Tracy A. Spalding, Allan K. Uldam
  • Tetrahydroquinoline analogues as muscarinic agonists
    Publication number: 20030176418
    Abstract: The present invention relates to tetrahydroquinoline compounds as muscarinic receptor agonists; compositions comprising the same; methods of inhibiting an activity of a muscarinic receptor with said compounds; methods of treating a disease condition associated with a muscarinic receptor using said compounds; and methods for identifying a subject suitable for treatment using said compounds.
    Type: Application
    Filed: December 23, 2002
    Publication date: September 18, 2003
    Inventors: Niels Skjaerbaek, Kristian Norup Koch, Bo Lennart Mikael Friberg, Bo-Ragnar Tolf
  • Compounds with activity on muscarinic receptors
    Publication number: 20030144285
    Abstract: Compounds and methods are provided for the alleviation or treatment of diseases or conditions in which modification of muscarinic m1 receptor activity has a beneficial effect. In the method, a therapeutically effective amount of a selective muscarinic m1 agonist compound is administered to a patient in need of such treatment.
    Type: Application
    Filed: January 7, 2003
    Publication date: July 31, 2003
    Inventors: Mark Brann, Terri Messier, Erika Currier, Kate Duggento, Tracy Spalding, Mikael Friberg, Niels Skjaerbaek
  • Compounds with activity on muscarinic receptors
    Patent number: 6528529
    Abstract: Compounds and methods are provided for the alleviation or treatment of diseases or conditions in which modification of muscarinic m1 receptor activity has a beneficial effect. In the method, a therapeutically effective amount of a selective muscarinic m1 agonist compound is administered to a patient in need of such treatment.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: March 4, 2003
    Assignee: Acadia Pharmaceuticals Inc.
    Inventors: Mark Brann, Terri Messier, Erika Currier, Kate Duggento, Tracy Spalding, Mikael Friberg, Niels Skjaerbaek
  • Muscarinic agonists
    Publication number: 20020037886
    Abstract: Compounds and methods are provided for the treatment of disease conditions in which modification of cholinergic, especially muscarinic m1, m4, or both m1 and m4, receptor activity has a beneficial effect. In the method, an effective amount of a compound is administered to a patient in need of such treatment.
    Type: Application
    Filed: April 27, 2001
    Publication date: March 28, 2002
    Inventors: Carl-Magnus A. Andersson, Bo Lennart M. Fribert, Niels Skjaerbaek, Tracy A. Spalding, Allan K. Uldam