Patents by Inventor Nikaïa Smith

Nikaïa Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCR4 receptor-binding compounds useful for increasing interferon level
    Patent number: 11433048
    Abstract: The invention relates to a CXCR4 receptor-binding compound for use for increasing or restoring interferon (IFN) level in an individual, wherein the interferon is a type-I interferon (IFN-I).
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: September 6, 2022
    Inventors: Nicolas Pietrancosta, Nikaïa Smith, Jean-Philippe Herbeuval
  • IMIDAZOLINE DERIVATIVES AS CXCR4 MODULATORS
    Publication number: 20220144853
    Abstract: The present invention provides novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds of formula (I) can act as CXCR4 modulators that specifically target the CXCR4 minor pocket, and they have further been found to inhibit the production of inflammatory cytokines in immune cells, which renders these compounds highly advantageous for use in therapy, particularly in the treatment or prevention of an inflammatory disorder, an autoimmune disorder, an autoinflammatory disorder, or an interferonopathy, such as, e.g., lupus erythematosus, dermatomyositis or rheumatoid arthritis.
    Type: Application
    Filed: March 27, 2020
    Publication date: May 12, 2022
    Applicants: Université de Paris, Centre National de la Recherche Scientifique
    Inventors: Nassima BEKADDOUR BENATIA, Mathieu RODERO, Jean-Philippe HERBEUVAL, Nicolas PIETRANCOSTA, Nikaïa SMITH, Anaïs BARRÉ, Julie CASSOU, Stanislas MAYER
  • CXCR4 RECEPTOR-BINDING COMPOUNDS USEFUL FOR INCREASING INTERFERON LEVEL
    Publication number: 20190175549
    Abstract: The invention relates to a CXCR4 receptor-binding compound for use for increasing or restoring interferon (IFN) level in an individual, wherein the interferon is a type-I interferon (IFN-I).
    Type: Application
    Filed: June 16, 2017
    Publication date: June 13, 2019
    Inventors: Nicolas Pietrancosta, Nikaïa Smith, Jean-Philippe Herbeuval
  • COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL
    Publication number: 20190175557
    Abstract: The invention relates to a CXCR4 receptor-binding compound for use for decreasing interferon (IFN) level in an individual.
    Type: Application
    Filed: June 16, 2017
    Publication date: June 13, 2019
    Inventors: Nicolas Pietrancosta, Nikaïa Smith, Jean-Philippe Herbeuval